The extremely low-frequency electromagnetic field (50 Hz) can establish a new "set-point" for the activity of the locus coeruleus-noradrenergic (LC-NA) system in rat.
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed rats to 50 Hz ELF-EMF at 1 mT or 7 mT for 1 hour/day over 7 days, repeated across three cycles, and assessed catecholamines, MHPG, β2-adrenergic receptor expression, and behavior. The authors report that ELF-EMF influences stress-response mechanisms involving the locus…
Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study exposed zebrafish embryos to 900 MHz RF-EMF for 30 or 60 minutes per day until 96 hours post-fertilization and assessed gene expression and physiological endpoints. The authors report reduced expression of lepa, ins, and pparg, changes in oxidative stress markers consistent with increased…
Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring.
Research
RF Safe Research Library
Jan 1, 2024
This rat study examined prenatal stress, prenatal ELF-EMF exposure, and their combination on adult male offspring outcomes at postnatal day 90. Prenatal stress increased serum corticosterone but did not change spatial memory, while combined stress+ELF-EMF disrupted memory acquisition. ELF-EMF exposure was associated…
The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…
Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…
Comparison of pulsed and continuous electromagnetic field generated by WPT system on human dermal and neural cells.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study tested electromagnetic fields generated by a prototype wireless power transfer (wireless charging) system on four human dermal and neural cell lines. Across pulsed and continuous exposure conditions, the authors report no negative effects on morphology/cytoskeleton, viability/mitosis,…
Spinning magnetic field patterns that cause oncolysis by oxidative stress in glioma cells
Research
RF Safe Research Library
Nov 7, 2023
This in vitro study characterized spinning oscillating magnetic field (sOMF) stimulation patterns that the authors report can induce cytotoxicity in two types of human glioma cells. The reported effect was linked to a critical rise in superoxide, and was reversed by the antioxidant Trolox, suggesting ROS involvement.…
Effects of prenatal mobile phone radiation exposure on MMP9 expression: Implications for inflammation, oxidative stress, and sensory-motor impairment after neonatal hypoxia- ischemia in rats
Research
RF Safe Research Library
Oct 13, 2023
This animal study examined whether prenatal mobile phone RF exposure affects brain injury markers and outcomes after neonatal hypoxia-ischemia in rats. The HI/Exposure group showed higher MMP-9 expression along with increased inflammatory and oxidative stress markers, larger infarct volume and edema, and worse…
Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined whether lipoic acid modifies cognitive and hippocampal effects in young male rats exposed to EMF emitted from multiple cell phones. The authors report improved learning performance but impaired long-term memory consolidation after EMF exposure, alongside changes in hippocampal…
Microstructure and Properties of Electromagnetic Field-Assisted Laser-Clad Norem02 Iron-Based Cemented Carbide Coating.
Research
RF Safe Research Library
Jan 1, 2023
This engineering study used electromagnetic field-assisted laser cladding to produce Norem02 iron-based cemented carbide coatings on 304 stainless steel and evaluated microstructure and mechanical-related properties. The abstract reports no change in phase composition but notable microstructural refinement and…
Seed Treatment with Electromagnetic Field Induces Different Effects on Emergence, Growth and Profiles of Biochemical Compounds in Seven Half-Sib Families of Silver Birch.
Research
RF Safe Research Library
Jan 1, 2023
This study evaluated a short (1 min) electromagnetic field (EMF) seed treatment in seven half-sib families of silver birch and assessed emergence, growth, and leaf biochemical profiles in one- and two-year-old seedlings. The abstract reports genotype- and age-dependent responses, with some families showing…
Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.
Research
RF Safe Research Library
Jan 1, 2023
This experimental mouse study tested whether N-acetylcysteine (NAC), pulsed electromagnetic fields (PEMF), or their combination improves outcomes after transplantation of vitrified ovarian tissue. The abstract reports increased follicle numbers and enhanced vascularization in NAC, PEMF, and NAC+PEMF groups, along…
Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2023
This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…
Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.
Research
RF Safe Research Library
Jan 1, 2023
This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…
Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…
Exposure to a 900 MHz electromagnetic field induces a response of the honey bee organism on the level of enzyme activity and the expression of stress-related genes.
Research
RF Safe Research Library
Jan 1, 2023
This animal study exposed one-day-old worker honey bees to 900 MHz RF-EMF at 12, 28, or 61 V/m for 15 minutes, 1 hour, or 3 hours, with an unexposed control group. The authors report changes in hemolymph enzyme activity and in expression of several stress-related genes following exposure. They state the pattern…
Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.
Research
RF Safe Research Library
Jan 1, 2023
This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…
Bidirectional Effect of Repeated Exposure to Extremely Low-Frequency Electromagnetic Field (50 Hz) of 1 and 7 mT on Oxidative/Antioxidative Status in Rat's Brain: The Prediction for the Vulnerability to Diseases.
Research
RF Safe Research Library
Jan 1, 2022
This rat study examined repeated 50 Hz ELF-EMF exposure (1 or 7 mT) and measured oxidative stress and antioxidant defense markers in the prefrontal cortex, including responses to a subsequent open-field stressor. The authors report intensity- and repetition-dependent effects: 1 mT produced weak changes and was…
No evidence for collateral effects of electromagnetic fields used to increase dissolved oxygen levels on the behavior and physiology of freshwater fishes.
Research
RF Safe Research Library
Jan 1, 2022
This animal study evaluated whether low-intensity EMF devices used to increase dissolved oxygen have collateral effects on freshwater fish. In captive sunfish, the authors report no significant differences in stress physiology biomarkers, behavior, or putative aerobic capacity between EMF and control conditions over…
Cardiac Cell Exposure to Electromagnetic Fields: Focus on Oxdative Stress and Apoptosis.
Research
RF Safe Research Library
Jan 1, 2022
This study assessed whether 915 MHz RF-EMF exposure alters oxidative stress and apoptosis markers in cardiac cells and mouse heart tissue. The authors report no statistically significant differences in apoptotic profile, antioxidant capacity, tissue integrity, or expression of apoptosis/antioxidant genes after…
Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…
Prioritizing health outcomes when assessing the effects of exposure to radiofrequency electromagnetic fields: A survey among experts.
Research
RF Safe Research Library
Jan 1, 2021
This paper reports a survey designed to prioritize which RF EMF-related health outcomes should be addressed in systematic reviews. Of 300 experts queried, 164 responded and rated cancer, heat-related effects, adverse birth/pregnancy outcomes, electromagnetic hypersensitivity, cognitive impairment, and oxidative…
Effects induced by a 50 Hz electromagnetic field and doxorubicin on Walker-256 carcinosarcoma growth and hepatic redox state in rats.
Research
RF Safe Research Library
Jan 1, 2021
This animal study compared 50 Hz extremely low-frequency EMF exposure with doxorubicin (and their combination) in Walker-256 carcinosarcoma-bearing rats, assessing tumor growth and liver redox-related outcomes. DOX and DOX+EMF were reported to inhibit tumor growth more than EMF alone, though EMF alone also showed an…
The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…
Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.
Research
RF Safe Research Library
Jan 1, 2021
This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…