Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring.
This rat study examined prenatal stress, prenatal ELF-EMF exposure, and their combination on adult male offspring outcomes at postnatal day 90. Prenatal stress increased serum corticosterone but did not change spatial memory, while combined stress+ELF-EMF disrupted memory acquisition. ELF-EMF exposure was associated with higher serum and hippocampal BDNF compared with the stress group, and the authors call for further mechanistic research.
Key points
- Female rats were assigned to control, prenatal stress, prenatal ELF-EMF, or combined stress+ELF-EMF groups (n=6 per group).
- Interventions occurred for 42 days spanning pre-pregnancy and pregnancy.
- Prenatal stress increased serum corticosterone in adult male offspring but did not affect spatial memory.
- Combined prenatal stress and ELF-EMF exposure disrupted the memory acquisition phase in the Morris Water Maze.
- Corticosterone levels did not change with combined stress+ELF-EMF compared with stress alone, per the abstract.
- Serum and hippocampal BDNF were higher in the ELF-EMF group compared with the stress group.
- The abstract does not report ELF-EMF frequency or field strength details.
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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