The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.
This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional apoptosis/oxidative-stress-related transcripts. They conclude these changes indicate potential effects of ELF-EMF on apoptosis and oxidative stress, with possible implications for endometrial function during peri-implantation.
Key points
- Porcine endometrial slices (n=5) were treated in vitro with 50 Hz ELF-EMF for 2 hours.
- The study assessed apoptosis and oxidative-stress-related markers at mRNA and protein/activity levels.
- CASP7 mRNA transcript and protein abundance were reported to decrease after ELF-EMF treatment.
- NOS3 (eNOS) mRNA transcript and protein abundance were reported to increase after ELF-EMF treatment.
- Additional apoptosis/oxidative-stress-related mRNA transcripts were reported to increase, but specific gene names are not fully legible in the provided abstract.
- The authors interpret the observed molecular changes as suggesting potential ELF-EMF effects on apoptosis and oxidative stress in endometrium.
Referenced studies & papers
Relevant papers in OpenMel
Source:
Open original
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
Comments
Log in to comment.
No comments yet.