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Variations of the spontaneous electrical activities of the neuronal networks imposed by the exposure of electromagnetic radiations using computational map-based modeling.

Research RF Safe Research Library Jan 1, 2023

This computational neuroscience study models a ring of three coupled Rulkov neurons to examine how electromagnetic induction may change spontaneous neuronal network activity. The abstract reports that magnetic field effects depend on the network’s initial dynamical regime and synaptic strength, including elimination…

A Swine Model of Traumatic Brain Injury: Effects of Neuronally Generated Electromagnetic Fields and Electromagnetic Field Stimulation on Traumatic Brain Injury-Related Changes.

Research RF Safe Research Library Jan 1, 2023

This animal feasibility study evaluated whether real-time measured, targeted sinusoidal EMF stimulation could normalize traumatic brain injury (TBI)-related changes in neuronally generated EMF patterns. In one Yucatan miniswine with controlled cortical impact, AI modeling distinguished pre-injury, post-injury, and…

A Swine Model of Changes in the Neuronal Electromagnetic Field After Traumatic Brain Injury: A Pilot Study.

Research RF Safe Research Library Jan 1, 2023

This pilot swine study evaluated whether non-contact proprietary induction sensors in a Mu-metal/copper mesh helmet can measure endogenous neuronal EMF signals before and after controlled cortical impact traumatic brain injury. The authors report that swine EMF recordings were distinguishable from room noise and…

Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Improves Neurological Outcome and Reduces Microglial Reactivity in a Rodent Model of Global Transient Stroke.

Research RF Safe Research Library Jan 1, 2023

This animal and laboratory study evaluated extremely low-frequency electromagnetic stimulation (ELF-EMS) in a rodent ischemia-reperfusion stroke model and related in vitro/slice experiments. The authors report improved neurological and behavioral outcomes, increased neuronal survival, and reduced glial/microglial…

Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.

Research RF Safe Research Library Jan 1, 2023

This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…

Electromagnetic field stimulation facilitates motor neuron excitability, myogenesis and muscle contractility in spinal cord transected rats.

Research RF Safe Research Library Jan 1, 2022

This animal study evaluated whole-body EMF stimulation in a rat model of complete spinal cord injury. Compared with SCI alone, EMF exposure for 7 or 14 days was reported to improve electrophysiological measures of motor neuron excitability and enhance soleus muscle contractile performance. Histopathology and protein…

EMF Antenna Exposure on a Multilayer Human Head Simulation for Alzheimer Disease Treatments.

Research RF Safe Research Library Jan 1, 2022

This study uses HFSS/EMPro simulations to model a 64 MHz antenna exposure on a multilayer human head to match parameters previously used in neuronal culture experiments. The simulations report achieving up to 0.6 W/kg maximum SAR and approximately 0.4–0.6 W/kg across head layers with a 1 A peak current pulse. The…

Measuring Electromagnetic Field Activity Generated by Neurons In Vivo by Humans With Thoughts of Repetitive Motor Activities and Emotional Thoughts.

Research RF Safe Research Library Jan 1, 2022

This study describes a helmet-based, non-contact method to continuously measure electromagnetic field activity associated with human brain neuronal activity during thought tasks. Volunteers performed motor movement, motor imagery, and emotional imagery while brain EMF was recorded. The authors report discernible…

Evaluating the Intrinsic Electromagnetic Field Generated by Neurons From Repetitive Motor Activities in Humans With a Non-contact Non-invasive Electromagnetic Helmet.

Research RF Safe Research Library Jan 1, 2022

This study reports a non-contact, non-invasive helmet system intended to measure intrinsic electromagnetic fields generated by the human brain during stereotyped motor tasks. Volunteers performed repetitive tapping, and the authors report discernible wave changes compared with rest and baseline measurements without a…

Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2021

This animal and primary neuron culture study exposed early postnatal mice to whole-body RF-EMF (SAR 4.0 W/kg) for 5 hours/day from P1 to P28. The authors report reductions in dendritic spine measures (notably mushroom-type spines), decreased glutamate receptor expression in mushroom-type spines, and lower BDNF…

Decreased dopamine in striatum and difficult locomotor recovery from MPTP insult after exposure to radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2019

This animal study reports that chronic RF-EMF exposure (835 MHz, SAR 4.0 W/kg, 5 h/day for 12 weeks) affected striatal neuronal markers in C57BL/6 mice. The authors observed reductions in synaptic vesicle-related measures and dopaminergic markers, including dopamine concentration and tyrosine hydroxylase expression.…

Acute exposure to high-induction electromagnetic field affects activity of model peripheral sensory neurons.

Research RF Safe Research Library Jan 1, 2018

This in vitro study examined acute low-frequency electromagnetic field (LF-EMF) exposure using high-induction magnetic stimulation in F11 cells, a dorsal root ganglia neuron-derived model of peripheral sensory neurons. Short-term exposure (

A Single Exposure to GSM-1800 MHz Signals in the Course of an Acute Neuroinflammatory Reaction can Alter Neuronal Responses and Microglial Morphology in the Rat Primary Auditory Cortex.

Research RF Safe Research Library Jan 1, 2018

This animal study examined whether acute GSM-1800 MHz exposure affects the auditory cortex during experimentally induced neuroinflammation. In LPS-treated rats, a single 2-hour head-only exposure (average SAR 1.55 W/kg in auditory cortex) was associated with altered microglial morphology and reduced neuronal activity…

Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2018

This study reports the identification of an electromagnetic perceptive gene (EPG) from glass catfish and its expression in mammalian cells, neuronal cultures, and rat brain. The authors report that magnetic/EMF stimulation remotely increased intracellular calcium in EPG-expressing cells and neurons. They also report…

Effects of 1800 MHz RF-EMF exposure on DNA damage and cellular functions in primary cultured neurogenic cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed primary cultured astrocytes, microglia, and cortical neurons to 1800 MHz RF-EMF at 4.0 W/kg SAR to assess DNA damage and cellular functions. The authors report no significant induction of γH2AX foci and no significant changes in cytokine secretion or dendrite/synapse morphological…

Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…

Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed Wistar rats to microwave radiation (30 mW/cm for 6 minutes, three times per week for six weeks) and assessed cognition, hippocampal dendritic spines, ultrastructure, and SNK-SPAR pathway molecules. The authors report impaired spatial learning and memory, dendritic spine loss/shrinkage, and…

Autophagy mediates the degradation of synaptic vesicles: A potential mechanism of synaptic plasticity injury induced by microwave exposure in rats.

Research RF Safe Research Library Jan 1, 2018

This animal study used an in vivo microwave exposure model (30 mW/cm) and reports reversible neuronal injuries in rats. The authors observed cognitive impairment and synaptic plasticity injury in hippocampal neurons following exposure. Autophagy was activated, and autophagosomes showed increased association with…

Weak electric fields detectability in a noisy neural network.

Research RF Safe Research Library Jan 1, 2017

This modeling study examines how a noisy spiking neural network detects a weak applied electric field using an Izhikevich neuron framework with excitatory/inhibitory neurons and conduction delays. The authors report stochastic resonance driven by white noise that enhances detectability, and that this effect largely…

Non-conductive and miniature fiber-optic imaging system for real-time detection of neuronal activity in time-varying electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This paper describes a non-conductive, miniature fiber-optic imaging system designed to record neuronal activity in real time during repetitive, long-term time-varying EMF exposure. Using the system, the authors report that short exposures (

Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…

Influence of the on-line ELF-EMF stimulation on the electrophysiological properties of the rat hippocampal CA1 neurons in vitro.

Research RF Safe Research Library Jan 1, 2017

This paper describes an on-line ELF magnetic stimulation setup and evaluates coil field distribution using COMSOL simulations alongside physical measurements. The authors report that modeled and measured magnetic flux densities were similar, and that stimulation induced sodium channel currents and fEPSPs in rat…

The expression of pluripotency and neuronal differentiation markers under the influence of electromagnetic field and nitric oxide.

Research RF Safe Research Library Jan 1, 2017

This in vitro study examined how 50 Hz low-frequency EMF and a nitric oxide donor (Deta-NO) affect stemness and neuronal differentiation markers in rat bone marrow mesenchymal stem cells. The authors report that high NO (1 mM) combined with EMF reduced stemness markers and increased neuronal differentiation markers,…

Stable morphological-physiological and neural protein expression changes in rat bone marrow mesenchymal stem cells treated with electromagnetic field and nitric oxide.

Research RF Safe Research Library Jan 1, 2017

This in vitro study evaluated combined effects of extremely low frequency EMF (50 Hz, 20 mT) and nitric oxide (NO) on rat bone marrow mesenchymal stem cells. The authors report reduced viability and morphology changes with high NO in the presence of EMF, along with increased calcium ion entry. They also report…

Effects of radiofrequency exposure emitted from a GSM mobile phone on proliferation, differentiation, and apoptosis of neural stem cells.

Research RF Safe Research Library Jan 1, 2017

This in vitro study evaluated adult murine neural stem cells exposed to GSM 900-MHz radiofrequency emissions from a mobile phone across different exposure durations. The authors report significant decreases in neurosphere number/size and neuronal differentiation with increasing exposure duration. They report no…

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