Expressions of some antioxidant genes in SH-SY5Y cells treated with β-lapachone, morphine and electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field under intermittent or continuous conditions, alongside β-lapachone and/or morphine. The authors report condition-dependent changes in antioxidant gene expression, including decreased NQO1 and increased NQO2 under intermittent EMF…
Gene Expression Analysis in Human Peripheral Blood Cells after 900 MHz RF-EMF Short-Term Exposure.
Research
RF Safe Research Library
Jan 1, 2018
This ex vivo/in vitro study exposed peripheral blood cells from five human donors to a 900 MHz continuous-wave RF-EMF for up to 90 minutes (average SAR 9.3 W/kg). After false discovery rate adjustment, the authors report no EMF-specific gene expression changes on microarray analysis. Although low-stringency analysis…
Extremely low-frequency electromagnetic fields accelerates wound healing modulating MMP-9 and inflammatory cytokines.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study used a scratch wound model in human immortalized keratinocytes (HaCaT) to examine effects of extremely low-frequency electromagnetic fields (ELF-EMF). ELF-EMF exposure was reported to accelerate wound closure compared with sham and to increase inflammatory cytokine expression/release. The authors…
Extremely low-frequency electromagnetic field (EMF) generates alterations in the synthesis and secretion of oestradiol-17β (E) in uterine tissues: An in vitro study.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed porcine endometrial and myometrial slices to extremely low-frequency EMF (50 or 120 Hz, 8 mT) for 2 or 4 hours, with or without progesterone. The authors report frequency- and time-dependent changes in oestradiol-17β secretion and CYP19A3 mRNA expression, with fewer changes when…
Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…
Structural features of hydroxyapatite and carbonated apatite formed under the influence of ultrasound and microwave radiation and their effect on the bioactivity of the nanomaterials.
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RF Safe Research Library
Jan 1, 2018
This study reports synthesizing hydroxyapatite and carbonate-substituted hydroxyapatite using ultrasound and microwave radiation as processing methods. The authors report that these physical factors produced calcium-deficient hydroxyapatite and B-type carbonated apatite and increased in vitro bioactivity compared…
Activation of TLR signalling regulates microwave radiation-mediated impairment of spermatogenesis in rat testis.
Research
RF Safe Research Library
Jan 1, 2018
This rat study examined whether microwave radiation affects Toll-like receptor (TLR) signaling in testis. The authors report increased TLR2-5 expression and elevated pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) after microwave exposure. Key phosphorylated components of TLR signaling (including NF-κB p65) were also…
After-effect induced by microwave radiation in human electroencephalographic signal: a feasibility study.
Research
RF Safe Research Library
Jan 1, 2018
This feasibility study tested whether microwave radiation (450 MHz, 40 Hz modulation; 1 g peak spatial average SAR 0.3 W/kg) can induce detectable event-related potentials in EEG. In one subject across four sessions, EEG responses time-locked to exposure offset showed increased alpha-band signal and about a twofold…
Biodegradable, pH-sensitive chitosan beads obtained under microwave radiation for advanced cell culture.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study describes microwave-assisted, green-chemistry synthesis of pH-sensitive chitosan beads crosslinked with a glutamic acid/1,5-pentanodiol mixture and optionally modified with Tilia platyphyllos extract. The beads were characterized (FT-IR, SEM), tested for swelling, pH sensitivity, antioxidant…
From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling.
Research
RF Safe Research Library
Jan 1, 2018
This mouse study examined low-level 2.45 GHz continuous-wave microwave exposure for 2 hours/day over 15, 30, or 60 days. The authors report impaired learning and spatial memory performance on an 8-arm radial maze after exposure. They also report increased corticosterone and stress/inflammatory-related markers with…
C-phycocyanin extraction assisted by pulsed electric field from Artrosphira platensis.
Research
RF Safe Research Library
Jan 1, 2017
This engineering/food-processing study evaluates pulsed electric field (PEF) treatment of fresh Artrhospira platensis biomass to enhance aqueous extraction of C-phycocyanin. Extraction depended on electric field strength, treatment time, and application temperature, with higher temperatures reducing the required…
Concept of Phase Cycling in Pulsed Magnetic Resonance Using Sinusoidal Magnetic Field Modulation.
Research
RF Safe Research Library
Jan 1, 2017
This article describes a signal-processing/measurement concept in pulsed magnetic resonance: achieving phase cycling through sinusoidal magnetic field modulation rather than changing pulse phases. The abstract states that modulation parameters can control spin precession phases, enabling separation of unwanted…
Quality stability and sensory attributes of apple juice processed by thermosonication, pulsed electric field and thermal processing.
Research
RF Safe Research Library
Jan 1, 2017
This study compared thermosonication, pulsed electric field, and thermal processing for preserving Royal Gala apple juice and evaluated sensory attributes and quality stability during 30 days of storage at 3°C and 20°C. Thermosonication and pulsed electric field produced juices with different taste compared with…
Effects of pH, temperature and pulsed electric fields on the turbidity and protein aggregation of ovomucin-depleted egg white.
Research
RF Safe Research Library
Jan 1, 2017
This laboratory study assessed how pH, temperature, and pulsed electric fields (PEF) affect turbidity and protein aggregation in ovomucin-depleted egg white solutions. Heating to 60°C for 10 minutes produced marked aggregation at several pH levels, while PEF caused some aggregation only at pH 5 and 7 under the…
RF-EMF exposure at 1800 MHz did not elicit DNA damage or abnormal cellular behaviors in different neurogenic cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study assessed whether intermittent 1800 MHz RF-EMF exposure induces DNA damage or alters cellular behavior in three neurogenic cell lines. Cells were exposed at an average SAR of 4.0 W/kg for 1, 6, or 24 hours and evaluated for γH2AX foci, cell cycle progression, proliferation, and viability. The…
Effects of electromagnetic fields on bone loss in hyperthyroidism rat model.
Research
RF Safe Research Library
Jan 1, 2017
This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…
Long-Term Evolution Electromagnetic Fields Exposure Modulates the Resting State EEG on Alpha and Beta Bands.
Research
RF Safe Research Library
Jan 1, 2017
This study evaluated whether exposure to EMF from an LTE system (described as equivalent to maximum LTE mobile phone emission) alters resting-state EEG. The abstract reports reduced spectral power and reduced interhemispheric coherence in alpha and beta bands in frontal and temporal regions. It also reports no…
Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…
Comments on "Association of excessive mobile phone use during pregnancy with birth weight: an adjunct study in Kumamoto of Japan Environment and Children's Study".
Research
RF Safe Research Library
Jan 1, 2017
This publication is a comment on a study reporting an association between excessive mobile phone use during pregnancy and birth weight. The authors argue the referenced study has shortcomings and cannot address whether ordinary mobile phone use during pregnancy leads to low birth weight. They note their prior…
Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation.
Research
RF Safe Research Library
Jan 1, 2017
This study assessed whether adding extremely low-frequency electromagnetic field (ELF-EMF) exposure to a 4-week poststroke rehabilitation program affects nitric oxide (NO)-related biomarkers and patient status. Forty-eight poststroke patients were assigned to ELF-EMF versus non-ELF-EMF rehabilitation, with the…
Mitigation measures of electromagnetic field exposure in the vicinity of high frequency welders.
Research
RF Safe Research Library
Jan 1, 2017
This paper describes in situ EMF measurements around industrial high frequency (dielectric) welders, framed by Polish labor safety regulations aligned with EU Directive 2013/35/EU. It reports real-world scenarios where excessive EMF exposure can occur near welders, often linked to errors or omissions during…
The expression of pluripotency and neuronal differentiation markers under the influence of electromagnetic field and nitric oxide.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study examined how 50 Hz low-frequency EMF and a nitric oxide donor (Deta-NO) affect stemness and neuronal differentiation markers in rat bone marrow mesenchymal stem cells. The authors report that high NO (1 mM) combined with EMF reduced stemness markers and increased neuronal differentiation markers,…
Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…
Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with increased telomerase reverse transcriptase gene expression.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed rat adipose-derived mesenchymal stem cells to 50 Hz, 20 mT ELF-EMF for 30 minutes per day over 21 days, with and without zinc sulfate. The authors report ELF-EMF exposure decreased TERT gene expression and increased senescent cells. Zinc sulfate was reported to increase TERT expression and…
Stable morphological-physiological and neural protein expression changes in rat bone marrow mesenchymal stem cells treated with electromagnetic field and nitric oxide.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study evaluated combined effects of extremely low frequency EMF (50 Hz, 20 mT) and nitric oxide (NO) on rat bone marrow mesenchymal stem cells. The authors report reduced viability and morphology changes with high NO in the presence of EMF, along with increased calcium ion entry. They also report…