Exposure to mobile phone (900-1800 MHz) during pregnancy: tissue oxidative stress after childbirth

Abstract

Exposure to mobile phone (900-1800 MHz) during pregnancy: tissue oxidative stress after childbirth Bahreyni Toossi MH, Sadeghnia HR, Mohammad Mahdizadeh Feyzabadi M, Hosseini M, Hedayati M, Mosallanejad R, Beheshti F, Alizadeh Rahvar Z. Exposure to mobile phone (900-1800 MHz) during pregnancy: tissue oxidative stress after childbirth. J Matern Fetal Neonatal Med. 2017 Apr 23:1-6. doi: 10.1080/14767058.2017.1315657. Abstract BACKGROUND: The present study has investigated the effects of mobile phone (900-1800 MHz)-induced electromagnetic radiation on redox status in the heart, liver, kidney, cerebellum, and hippocampus of dams and the offspring mice. MATERIALS AND METHODS: Pregnant Balb/C were divided into two groups including the control and the experimental group. The experimental group was exposed to mobile phone (900-1800 MHz), during pregnancy (2 h/d for 20 d). The dams and the offspring of both groups were sacrificed and tissues of interest were harvested immediately after delivery. Malondialdehyde (MDA) concentration, total thiol groups (TTG) content, superoxide dismutase (SOD), and catalase (CAT) activities were determined in the tissues. RESULTS: In the experimental groups, MDA levels were significantly increased, while TTG, SOD, and CAT were significantly decreased in the total tissues of dams and their offspring. CONCLUSION: Exposure to mobile phone (900-1800 MHz) during pregnancy induced oxidative stress in tissues of dams and their offspring. ncbi.nlm.nih.gov

AI evidence extraction

Main findings

Compared with controls, the exposed group showed significantly increased MDA and significantly decreased TTG, SOD, and CAT across the assessed tissues in dams and their offspring after delivery.

Outcomes measured

• Malondialdehyde (MDA) concentration
• Total thiol groups (TTG) content
• Superoxide dismutase (SOD) activity
• Catalase (CAT) activity
• Oxidative stress/redox status in heart, liver, kidney, cerebellum, hippocampus (dams and offspring)

Limitations

• Sample size not reported in provided abstract/metadata
• Exposure characterization limited to frequency range and duration; SAR/dosimetry not reported
• Only oxidative stress biomarkers reported; no clinical/functional outcomes described

Suggested hubs

• mobile-phones (0.9)
  Exposure source is mobile phone RF (900–1800 MHz) during pregnancy.

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    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "mobile phone",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "2 h/d for 20 d (during pregnancy)"
    },
    "population": "Pregnant Balb/C mice (dams) and their offspring",
    "sample_size": null,
    "outcomes": [
        "Malondialdehyde (MDA) concentration",
        "Total thiol groups (TTG) content",
        "Superoxide dismutase (SOD) activity",
        "Catalase (CAT) activity",
        "Oxidative stress/redox status in heart, liver, kidney, cerebellum, hippocampus (dams and offspring)"
    ],
    "main_findings": "Compared with controls, the exposed group showed significantly increased MDA and significantly decreased TTG, SOD, and CAT across the assessed tissues in dams and their offspring after delivery.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in provided abstract/metadata",
        "Exposure characterization limited to frequency range and duration; SAR/dosimetry not reported",
        "Only oxidative stress biomarkers reported; no clinical/functional outcomes described"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "mobile phone",
        "900-1800 MHz",
        "pregnancy",
        "mice",
        "offspring",
        "oxidative stress",
        "MDA",
        "SOD",
        "catalase",
        "thiol groups",
        "heart",
        "liver",
        "kidney",
        "cerebellum",
        "hippocampus"
    ],
    "suggested_hubs": [
        {
            "slug": "mobile-phones",
            "weight": 0.90000000000000002220446049250313080847263336181640625,
            "reason": "Exposure source is mobile phone RF (900–1800 MHz) during pregnancy."
        }
    ]
}

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