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Showing results for: hippocampus

Dose-dependent impact of extremely low-frequency electromagnetic field (ELF-EMF) on the neuroplasticity in the hippocampus of adult rats.

Research RF Safe Research Library Jan 1, 2026

This animal study examined whether 50 Hz ELF-EMF exposure at two intensities (1 mT vs 7 mT) alters hippocampal gene transcripts related to neuroplasticity and cell survival in adult rats across repeated exposure cycles. The authors report intensity- and exposure-number-dependent modulation of mRNA expression, with 1…

Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…

Effects of short and long term electromagnetic fields exposure on the human hippocampus.

Research RF Safe Research Library Jan 1, 2017

This study compared 60 healthy female medical students grouped by self-reported daily mobile phone use by the head (90 min). MRI/MRS analyses found no significant differences in hippocampal volume or in choline, creatine, and N-acetyl aspartate between groups. However, the higher-use group showed poorer performance…

Theta-gamma coupling in hippocampus during working memory deficits induced by low frequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2017

This mouse study examined whether 50 Hz, 1 mT electromagnetic field exposure affects working memory and hippocampal electrophysiology. The authors report reduced Y-maze working memory performance after 3 days of EMF exposure, accompanied by decreased hippocampal firing rates. They also report reduced theta and…

Effects of Electromagnetic Radiation from Smartphones on Learning Ability and Hippocampal Progenitor Cell Proliferation in Mice.

Research RF Safe Research Library Jan 1, 2016

This mouse study examined chronic smartphone electromagnetic radiation exposure and its effects on spatial working memory and hippocampal progenitor cell proliferation. The authors report no significant differences in Y-maze spontaneous alternation or BrdU-labeled progenitor proliferation after exposure, but…

Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats

Research RF Safe Research Library Mar 19, 2015

This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…

Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats

Research RF Safe Research Library Jan 1, 2014

This animal study examined 2.45 GHz Wi-Fi exposure in a PTZ-induced epilepsy rat model using freshly isolated hippocampal and DRG neurons. The authors report that epilepsy increased Ca(2+) influx, oxidative stress markers, and apoptosis-related outcomes, and that Wi-Fi exposure produced additional increases in…

Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload.

Research RF Safe Research Library Jan 1, 2014

This animal study tested whether 900 MHz EMF exposure, alone or combined with brain iron overload, affects cognition and brain biochemistry in Long-Evans rats. EMF-exposed rats showed impairment in an object exploration task and changes in monoamine content (notably in the hippocampus), while other spatial…

[A aquaporin 4 expression and effects in rat hippocampus after microwave radiation].

Research RF Safe Research Library Jan 1, 2009

This rat study examined hippocampal aquaporin 4 (AQP4) expression after microwave exposure at 10, 30, or 100 mW/cm^2. The authors report increased AQP4 protein and gene expression after exposure, with recovery at lower power density but more persistent elevation at higher power density. They conclude that increased…

[Influence of electromagnetic radiation on raf kinase inhibitor protein and its related proteins of hippocampus].

Research RF Safe Research Library Jan 1, 2008

This rat study examined hippocampal RKIP and related markers after exposure to high power microwaves (X-band and S-band) or an electromagnetic pulse. RKIP protein decreased at 6 hours post-exposure, with recovery by 1 day in the EMP group but more prolonged decreases (up to ~7 days) in the microwave groups.…

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