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Showing results for: proteins

Non‑Thermal RF Biological Effects Are Documented—Thermal‑Only Wireless Safety Standards Are Not Scientifically Adequate

Research Effect Synthesis Mar 6, 2026

Synthesis of 13 curated studies (2006–2025) showing non-thermal RF effects—oxidative stress, fertility impacts, and animal tumor evidence—plus regulatory gaps. Conclusion: thermal-only RF limits are incomplete; precau…

Non‑Thermal EMF Harm Signals (Moderate Evidence): Reproductive DNA Damage, Pregnancy Risk, Tumor Relevance, and Ecological Disruption

Research Effect Synthesis Mar 1, 2026

Synthesis of 13 moderate-evidence harm papers: 5G-band RF increased sperm DNA fragmentation in vitro; pregnancy cohort linked call time to miscarriage and growth outcomes; lifetime RFR tumor genetics support translati…

Alpha-Lipoic Acid Preserves Testicular Integrity Under 2.45 GHz Electromagnetic Radiation by Restoring Redox and Inflammatory Balance

Research RF Safe Research Library Jan 1, 2025

This animal study exposed adult male rats to 2.45 GHz electromagnetic radiation for 2 hours/day for one month and assessed testicular outcomes. The abstract reports that EMR exposure induced oxidative stress, increased inflammatory markers, and caused histological testicular injury. Alpha-lipoic acid supplementation…

Electromagnetic Field Stimulation Effects on Intrinsically Disordered Proteins and Their Role in Aging and Neurodegeneration

Research RF Safe Research Library Jan 1, 2025

This review discusses preclinical studies suggesting non-ionizing EMF exposures can produce beneficial biological effects, while noting ongoing controversy about mechanisms. It reports evidence of EMF-associated conformational changes in intrinsically disordered proteins relevant to neurodegeneration and describes RF…

Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development

Research RF Safe Research Library Jan 1, 2025

This in vitro study reports that radiofrequency (RF) exposure in the 800–2,400 MHz range modulates differentiation pathways in human cortical organoids derived from embryonic stem cells. RF exposure is described as maintaining radial glia stem cell identity and delaying differentiation, alongside induction of…

Magnetic effects in biology: Crucial role of quantum coherence in the radical pair mechanism

Research RF Safe Research Library Jan 1, 2025

This theoretical biophysics study models the radical pair mechanism as an open quantum system to derive an explicit dependence of magnetic-field effects on the spin coherence relaxation time (τ) and chemical kinetics (k). It reports a condition under which RPM effects become significant and estimates τ in…

Proteomic Characterization of Human Peripheral Blood Mononuclear Cells Exposed to a 50 Hz Magnetic Field

Research RF Safe Research Library Jan 1, 2025

This in vitro study compared proteomic profiles of PBMCs from three human donors after 24-hour exposure to a 50 Hz, 1 mT extremely low-frequency magnetic field versus unexposed cells. The abstract reports broad protein expression changes, including upregulation of proteins associated with metabolic processes and…

Electromagnetic fields regulate iron metabolism: From mechanisms to applications

Research RF Safe Research Library Jan 1, 2025

This review synthesizes evidence that electromagnetic field (EMF) exposure is associated in the literature with changes in systemic and cellular iron metabolism, with reported effects varying by EMF parameters, exposure duration, and biological context. It proposes mechanistic pathways involving iron-containing…

Acute exposure to 27.12 MHz radiofrequency electromagnetic field disrupts blood-brain barrier integrity via eNOS activation and occludin down-regulation.

Research RF Safe Research Library Jan 1, 2025

This animal study examined 27.12 MHz RF-EMF exposure for 30, 180, or 360 minutes in female Wistar rats and assessed markers related to blood-brain barrier integrity. The authors report increased eNOS expression after 30 minutes without oxidative stress or inflammation, alongside decreased occludin expression. Longer…

The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…

Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices from days 15–16 of pregnancy to a 50 Hz extremely low-frequency electromagnetic field for 2 hours. The authors report changes in several epigenetic-related markers, including DNA methylation machinery, histone-related measures (HDAC activity), global DNA…

First Identification of the Effects of Low Frequency Electromagnetic Field on the Micromolecular Changes in Adipose Tissue-Derived Mesenchymal Stem Cells by Fourier Transform Infrared Spectroscopy.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed adipose tissue-derived mesenchymal stem cells to a continuous 50 Hz electromagnetic field at 1.5 mT for 24, 48, or 72 hours and assessed micromolecular changes using FTIR spectroscopy. The authors report the largest FTIR spectral differences versus control in nucleic acids and proteins…

Synergistic effect of electromagnetic fields and nanomagnetic particles on osteogenesis through calcium channels and p-ERK signaling.

Research RF Safe Research Library Jan 1, 2021

This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…

Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression.

Research RF Safe Research Library Jan 1, 2019

This study assessed pre-sowing sunflower seed treatments using vacuum, 5.28 MHz radio-frequency cold plasma, and an electromagnetic field for varying durations. The authors report faster germination with cold plasma (7 min) and EMF (15 min), while germination percentage was mostly unchanged except for a decrease…

Effect of Modified Wuzi Yanzong Pill () on Tip60-Mediated Apoptosis in Testis of Male Rats after Microwave Radiation.

Research RF Safe Research Library Jan 1, 2019

This animal study exposed male rats to a single 15-minute microwave radiation session and assessed testicular apoptosis, histopathology, and related proteins. The radiation group showed increased apoptosis and testicular structural alterations versus controls at multiple time points, while a modified Wuzi Yanzong…

2.45 GHz microwave radiation induced oxidative and nitrosative stress mediated testicular apoptosis: Involvement of a p53 dependent bax-caspase-3 mediated pathway.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed 12-week-old male mice to 2.45 GHz continuous-wave microwave radiation (average power density 0.0248 mW/cm; whole-body SAR 0.0146 W/kg) for 2 hours/day over 15, 30, or 60 days. The authors evaluated testicular histology, testosterone, oxidative/nitrosative stress markers, antioxidant enzymes,…

Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed human fetal and adult fibroblasts to 25 GHz microwave radiation and assessed multiple genotoxic and cellular endpoints. The authors report no evidence of direct DNA damage and no apoptosis or changes in prosurvival signalling proteins. However, they report increased total and…

Effects of pH, temperature and pulsed electric fields on the turbidity and protein aggregation of ovomucin-depleted egg white.

Research RF Safe Research Library Jan 1, 2017

This laboratory study assessed how pH, temperature, and pulsed electric fields (PEF) affect turbidity and protein aggregation in ovomucin-depleted egg white solutions. Heating to 60°C for 10 minutes produced marked aggregation at several pH levels, while PEF caused some aggregation only at pH 5 and 7 under the…

Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.

Research RF Safe Research Library Jan 1, 2017

This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…

Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.

Research RF Safe Research Library Jan 1, 2016

This in vitro study examined how Salmonella enterica serovar Hadar adapts to a 200 mT static magnetic field for 9 hours using proteomics. The authors report 35 cytosolic proteins with >2-fold expression changes after exposure, spanning metabolism, oxidative stress response, energy homeostasis, translation elongation,…

Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis

Research RF Safe Research Library Jan 1, 2014

This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…

Effect of 60 minutes exposure to electromagnetic field on fecundity, learning and memory, speed of movement and whole body protein of the fruit fly Drosophila melanogaster.

Research RF Safe Research Library Jan 1, 2012

This animal study exposed Drosophila melanogaster to EMF from four electrical devices for 60 minutes and assessed fecundity, larval behavior, and protein patterns. The authors report no significant effect on adult fecundity, but report changes in larval learning/memory and movement speed, with the largest effects in…

Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.

Research RF Safe Research Library Jan 1, 2012

This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…

[Influence of electromagnetic radiation on raf kinase inhibitor protein and its related proteins of hippocampus].

Research RF Safe Research Library Jan 1, 2008

This rat study examined hippocampal RKIP and related markers after exposure to high power microwaves (X-band and S-band) or an electromagnetic pulse. RKIP protein decreased at 6 hours post-exposure, with recovery by 1 day in the EMP group but more prolonged decreases (up to ~7 days) in the microwave groups.…

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