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6 postsAlpha-Lipoic Acid Preserves Testicular Integrity Under 2.45 GHz Electromagnetic Radiation by Restoring Redox and Inflammatory Balance
This animal study exposed adult male rats to 2.45 GHz electromagnetic radiation for 2 hours/day for one month and assessed testicular outcomes. The abstract reports that EMR exposure induced oxidative stress, increased inflammatory markers, and caused histological testicular injury. Alpha-lipoic acid supplementation was reported to mitigate these changes and restore several testicular proteins.
Electromagnetic Field Stimulation Effects on Intrinsically Disordered Proteins and Their Role in Aging and Neurodegeneration
This review discusses preclinical studies suggesting non-ionizing EMF exposures can produce beneficial biological effects, while noting ongoing controversy about mechanisms. It reports evidence of EMF-associated conformational changes in intrinsically disordered proteins relevant to neurodegeneration and describes RF exposure conditions that activate proteostasis and autophagy in cell and animal models. The authors propose a quantum-biophysical framework involving the water-protein interface and suggest potential human applications within regulatory safety thresholds.
Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development
This in vitro study reports that radiofrequency (RF) exposure in the 800–2,400 MHz range modulates differentiation pathways in human cortical organoids derived from embryonic stem cells. RF exposure is described as maintaining radial glia stem cell identity and delaying differentiation, alongside induction of endogenous retrovirus expression and increased expression of ASD-associated genes and retroelements. The abstract attributes these effects to dysregulation of BET proteins and reports that BET inhibition rescues the RF-associated developmental defects.
Magnetic effects in biology: Crucial role of quantum coherence in the radical pair mechanism
This theoretical biophysics study models the radical pair mechanism as an open quantum system to derive an explicit dependence of magnetic-field effects on the spin coherence relaxation time (τ) and chemical kinetics (k). It reports a condition under which RPM effects become significant and estimates τ in cryptochrome-like proteins to be on the order of units to tens of nanoseconds. The paper also reports that nanoTesla-level radio-frequency fields have minor influence and are unlikely to disrupt RPM patterns under the modeled decoherence.
Proteomic Characterization of Human Peripheral Blood Mononuclear Cells Exposed to a 50 Hz Magnetic Field
This in vitro study compared proteomic profiles of PBMCs from three human donors after 24-hour exposure to a 50 Hz, 1 mT extremely low-frequency magnetic field versus unexposed cells. The abstract reports broad protein expression changes, including upregulation of proteins associated with metabolic processes and downregulation of proteins linked to T cell costimulation/activation and immune processes. No effects were observed on cell proliferation, viability, or cell cycle progression. The authors interpret the proteomic shifts as metabolic reprogramming with potential implications for immune regulation.
Electromagnetic fields regulate iron metabolism: From mechanisms to applications
This review synthesizes evidence that electromagnetic field (EMF) exposure is associated in the literature with changes in systemic and cellular iron metabolism, with reported effects varying by EMF parameters, exposure duration, and biological context. It proposes mechanistic pathways involving iron-containing proteins/tissues, membrane and ion channel modulation, and reactive oxygen species (ROS). The authors frame iron-metabolism modulation as relevant to both therapeutic applications and safety evaluation, while emphasizing inconsistencies and the need for standardized exposure protocols.