2.45 GHz microwave radiation induced oxidative and nitrosative stress mediated testicular apoptosis: Involvement of a p53 dependent bax-caspase-3 mediated pathway.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed 12-week-old male mice to 2.45 GHz continuous-wave microwave radiation (average power density 0.0248 mW/cm; whole-body SAR 0.0146 W/kg) for 2 hours/day over 15, 30, or 60 days. The authors evaluated testicular histology, testosterone, oxidative/nitrosative stress markers, antioxidant enzymes,…
Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human fetal and adult fibroblasts to 25 GHz microwave radiation and assessed multiple genotoxic and cellular endpoints. The authors report no evidence of direct DNA damage and no apoptosis or changes in prosurvival signalling proteins. However, they report increased total and…
Effects of pH, temperature and pulsed electric fields on the turbidity and protein aggregation of ovomucin-depleted egg white.
Research
RF Safe Research Library
Jan 1, 2017
This laboratory study assessed how pH, temperature, and pulsed electric fields (PEF) affect turbidity and protein aggregation in ovomucin-depleted egg white solutions. Heating to 60°C for 10 minutes produced marked aggregation at several pH levels, while PEF caused some aggregation only at pH 5 and 7 under the…
Stable morphological-physiological and neural protein expression changes in rat bone marrow mesenchymal stem cells treated with electromagnetic field and nitric oxide.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study evaluated combined effects of extremely low frequency EMF (50 Hz, 20 mT) and nitric oxide (NO) on rat bone marrow mesenchymal stem cells. The authors report reduced viability and morphology changes with high NO in the presence of EMF, along with increased calcium ion entry. They also report…
Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…
Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy.
Research
RF Safe Research Library
Jan 1, 2017
This study reports a technology that records a specific radiofrequency electromagnetic energy signal associated with EGFR siRNA and applies it to cells. The abstract describes reductions in EGFR mRNA and protein expression versus controls, with specificity assessed using RNA microarray and antibody dot blot array. It…
Alterations of Immune Parameters on Trichoplusia ni (Lepidoptera: Noctuidae) Larvae Exposed to Extremely Low-Frequency Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed Trichoplusia ni larvae to 60 Hz, 2.0 mT ELF-EMF for 24, 48, or 72 hours and assessed immune parameters and fertility. The abstract reports no effect on life cycle and fertility after 24 hours, but several immune-related measures changed after 48–72 hours, including reduced hemolymph protein…
Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…
Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation.
Research
RF Safe Research Library
Jan 1, 2017
This study investigated 2 nm protein-stabilized gold nanoclusters in six mammalian cell types under 1 GHz electromagnetic field exposure. The authors report low intrinsic toxicity of the nanoclusters, but a significant decrease in cell viability when nanocluster-incubated cells were exposed to the 1 GHz field,…
[Genic and non-genic regulation of low frequence pulsed electromagnetic fields on osteoblasts differentiation].
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study exposed rat calvarial osteoblasts to 50 Hz, 0.6 mT pulsed electromagnetic fields for 1.5 hours and measured early differentiation-related markers over 0–12 hours. The abstract reports increased ALP activity at 3 hours and time-dependent changes in ALP, Runx2, and OSX transcription and Runx2/OSX…
Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.
Research
RF Safe Research Library
Jan 1, 2016
This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…
Unraveling the effects of static magnetic field stress on cytosolic proteins of Salmonella by using a proteomic approach.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study examined how Salmonella enterica serovar Hadar adapts to a 200 mT static magnetic field for 9 hours using proteomics. The authors report 35 cytosolic proteins with >2-fold expression changes after exposure, spanning metabolism, oxidative stress response, energy homeostasis, translation elongation,…
The effects of radio-frequency electromagnetic fields on T cell function during development
Research
RF Safe Research Library
Jan 1, 2015
This animal study exposed developing Sprague Dawley rats to 2.14 GHz W-CDMA RF-EMF at a whole-body SAR of 0.2 W/kg for 9 weeks (20 h/day). No differences were reported in multiple T cell population measures across blood, spleen, and thymus. Some Th1/Th2-related genes were upregulated (notably in thymus), but serum…
[Modulation of Ca(2+)-Dependent Proteiolysis under the Action of Weak Low-Frequency Magnetic Fields].
Research
RF Safe Research Library
Jan 1, 2015
This animal/model-organism study examined whether weak low-frequency magnetic fields tuned to a proposed parametric resonance for calcium ions affect Ca(2+)-dependent proteolysis. It reports time-dependent modulation of Ca(2+)-dependent proteinase activity in fish and whelk and states that a minimal exposure time for…
Gamma radiation and magnetic field mediated delay in effect of accelerated ageing of soybean.
Research
RF Safe Research Library
Jan 1, 2015
This study evaluated gamma radiation and static magnetic field treatments on soybean seeds stored for six months and then subjected to accelerated ageing. The authors report that certain gamma doses (3–5 kGy) and magnetic field strengths (100–200 mT) helped maintain seed protein/oil characteristics and antioxidant…
Effect of ELF-EMF Exposure on Human Neuroblastoma Cell Line: a Proteomics Analysis
Research
RF Safe Research Library
Jan 1, 2014
This in vitro study exposed SH-SY5Y human neuroblastoma cells to a 2 mT, 50 Hz magnetic field for 3 hours and assessed protein expression using proteomics. The authors report that 189 proteins changed expression in exposed cells compared with controls, with PCA/clustering separating samples by condition. They…
Effect of 950 MHz UHF electromagnetic radiation on biomarkers of oxidative damage, metabolism of UFA and antioxidants in the livers of young rats of different ages
Research
RF Safe Research Library
Jan 1, 2014
This animal study exposed rats of different early-life ages to 950 MHz UHF electromagnetic radiation for 30 minutes per day (SAR 1.0–1.3 W/kg) across gestation and/or early postnatal periods. The authors report no evidence of oxidative stress by TBARS or protein carbonyls, but report changes in fatty acid…
Suppression of unimolecular decay of laser desorbed peptide and protein ions by entrainment in rarefied supersonic gas jets under weak electric fields.
Research
RF Safe Research Library
Jan 1, 2014
This engineering-focused paper reports the design principle and performance of a MALDI ion source ("MALDI-2") combining rarefied supersonic gas jets with weak electric fields and injection into gas-filled RF multipoles. The abstract reports rapid collisional cooling (
Assessing of plasma protein denaturation induced by exposure to cadmium, electromagnetic fields and their combined actions on rat.
Research
RF Safe Research Library
Jan 1, 2014
This animal study examined whether cadmium, EMF exposure, or their combination affects oxidative damage and protein structure in rat plasma. The authors report increased oxidative protein damage markers and changes in protein-related measures after cadmium and/or EMF exposure. Effects were described as more…
[The effect of weak low-frequency magnetic fields on the intracellular calcium-dependent proteinases of fish].
Research
RF Safe Research Library
Jan 1, 2013
This animal study examined in vivo and in vitro effects of weak, low-frequency magnetic fields described as having resonance parameters for calcium ions. The authors report a considerable decrease in activity of calcium-dependent proteinases (calpains) in fish skeletal muscle and brain following exposure. The…
[Modulation of Ca(2+)-dependent proteinase activity in invertebrates and fish under the action of weak low-frequency magnetic fields].
Research
RF Safe Research Library
Jan 1, 2013
This study examined whether weak low-frequency magnetic fields affect Ca2+-dependent proteinases (calpains) in fish and invertebrates using in vivo and in vitro experiments. The authors report a significant decrease in calpain activity in animals exposed to a field tuned to Ca2+ parametric resonance, and substantial…
Effect of puerarin on matrix metalloproteinase-2 in human fetal scleral fibroblasts treated with low frequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2013
This in vitro study examined whether extremely low frequency electromagnetic field (ELF-EMF) exposure alters MMP-2 expression in cultured human fetal scleral fibroblasts and whether puerarin modifies this response. The authors report increased MMP-2 mRNA and protein expression after 0.2 mT ELF-EMF exposure for 24…
Effect of 60 minutes exposure to electromagnetic field on fecundity, learning and memory, speed of movement and whole body protein of the fruit fly Drosophila melanogaster.
Research
RF Safe Research Library
Jan 1, 2012
This animal study exposed Drosophila melanogaster to EMF from four electrical devices for 60 minutes and assessed fecundity, larval behavior, and protein patterns. The authors report no significant effect on adult fecundity, but report changes in larval learning/memory and movement speed, with the largest effects in…
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…
Down-regulation of metallothionein 1 and 2 after exposure to electromagnetic field in mouse testis.
Research
RF Safe Research Library
Jan 1, 2011
This animal study examined mouse testis after 8 weeks of exposure to a 3 MT electromagnetic field (4 hours/day). The authors report significant histological changes (increased primary spermatocytes, increased Leydig cells, and increased basement membrane thickness) in exposed mice versus controls. MT1 and MT2…