Mg.ATP-decorated ultrafine magnetic nanofibers: A bone scaffold with high osteogenic and antibacterial properties in the presence of an electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study developed magnetic electrospun nanofibers for bone regeneration and evaluated osteogenic and antibacterial properties. Functionalization with ATP and Mg increased mesenchymal stem cell adhesion, proliferation, and osteogenic marker readouts compared with unmodified fibers. The authors report that…
Enhancement of Fungal Enzyme Production by Radio-Frequency Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined whether a 2 GHz RF-EMF exposure could enhance enzyme production in a filamentous fungus. A 10-minute exposure was reported to increase extracellular total protein and α-amylase activity in culture media versus controls, alongside increased α-amylase mRNA and changes consistent with…
Static and Electromagnetic Fields Differently Affect Proliferation and Cell Death Through Acid Enhancement of ROS Generation in Mesenchymal Stem Cells.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined how a 20 mT static magnetic field and a 20 mT 50 Hz electromagnetic field affect mesenchymal stem cells under conditions involving ROS and acidic pH. The authors report increased ROS and antioxidant-response markers (Nrf2, SOD2, GST) across SMF, EMF, and combined exposures, with…
Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined LTE RF-EMF exposure effects on SH-SY5Y neuroblastoma cells. The authors report reduced cell proliferation and a G0/G1 cell-cycle delay after 1760 MHz exposure at 4 W/kg for 4 hr/day over 4 days. They report no marked DNA damage signal (γH2AX) and no apoptosis activation, but increased…
Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.
Research
RF Safe Research Library
Jan 1, 2021
This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…
Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…
Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma
Research
RF Safe Research Library
Jan 1, 2021
This pooled case series evaluated amplitude-modulated 27.12 MHz RF EMF delivered via the TheraBionic P1 device (3 hours daily) in patients with advanced hepatocellular carcinoma, comparing outcomes to historical controls. The authors report longer median overall survival for Child-Pugh A patients versus comparable…
[Electromagnetic field in the environment - estimation methods and monitoring].
Research
RF Safe Research Library
Jan 1, 2019
This paper discusses the legal context for environmental EMF measurements and describes methods for estimating EMF intensity from multiple sources, particularly cellular base stations. It presents an engineering concept for mobile EMF monitoring and reports verification testing of the measurement setup. Field…
Impact of extremely low-frequency electromagnetic field (100 Hz, 100 G) exposure on human glioblastoma U87 cells during Temozolomide administration.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study evaluated whether extremely low-frequency EMF exposure (100 Hz, 100 G) modifies the effects of temozolomide (100 µM) in human glioblastoma U87 cells over 120–144 hours. The authors report that combined treatment reduced stemness-associated markers (Nestin, CD133, Notch4) and increased GFAP…
Hepatocellular carcinoma therapy finds a channel on the radio
Research
RF Safe Research Library
Jan 1, 2019
This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…
Estimating transmitted power density from mobile phone: an epidemiological pilot study with a software modified phone.
Research
RF Safe Research Library
Jan 1, 2018
This pilot study evaluated weekly and annual cumulative RF-EMF exposure attributed to mobile phone use using objective phone-based measurements of transmitted and received power densities. Ten participants provided two months of daily data across usage modes (cellular calls, cellular data, and Wi-Fi). The study…
A 60 Hz uniform electromagnetic field promotes human cell proliferation by decreasing intracellular reactive oxygen species levels.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined effects of a 6 mT, 60 Hz uniform ELF electromagnetic field on HeLa cells and primary IMR-90 fibroblasts. Single or repetitive exposure did not induce DNA damage or change viability, but continuous exposure over 168 hours was reported to increase proliferation in both cell types in a…
AN EMPIRICAL STUDY: THE IMPACT OF THE NUMBER OF USERS ON ELECTRIC FIELD STRENGTH OF WIRELESS COMMUNICATIONS.
Research
RF Safe Research Library
Jan 1, 2018
This study used real-time measurements on a university campus to examine how the number of users relates to RF electric field strength from cellular systems and a Wi-Fi access point. The authors report empirical models that estimate E from user counts, with stated accuracies of 86% for cellular-related measurements…
Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2018
This study reports the identification of an electromagnetic perceptive gene (EPG) from glass catfish and its expression in mammalian cells, neuronal cultures, and rat brain. The authors report that magnetic/EMF stimulation remotely increased intracellular calcium in EPG-expressing cells and neurons. They also report…
Changes of cationic transport in AtCAX5 transformant yeast by electromagnetic field environments.
Research
RF Safe Research Library
Jan 1, 2018
This laboratory study examined cation transport and intracellular ion levels in a yeast strain (K667) with controlled expression of the plant cation/H+ exchanger AtCAX5 under metallic stress and ELF magnetic-field exposure. Cultures exposed to 60 Hz, 0.1 mT sinusoidal or square-wave magnetic fields showed increased…
Low frequency electromagnetic field decreases ischemia-reperfusion injury of human cardiomyocytes and supports their metabolic function.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study tested whether extremely low frequency/low frequency electromagnetic field (LF-EMF) exposure modifies ischemia-reperfusion injury in human cardiac-related cell types. Using LDH and MMP-2 activities and fluorescein diacetate staining, the authors report that short courses of LF-EMF reduced cellular…
Extremely low frequency electromagnetic fields promote mesenchymal stem cell migration by increasing intracellular Ca and activating the FAK/Rho GTPases signaling pathways in vitro.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human bone marrow-derived mesenchymal stem cells to extremely low frequency EMF (7.5–70 Hz, 1 mT) generated by Helmholtz coils. The authors report increased MSC migration across all tested frequencies. Mechanistically, the effect is described as dependent on intracellular calcium and…
Effects of 1800 MHz RF-EMF exposure on DNA damage and cellular functions in primary cultured neurogenic cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed primary cultured astrocytes, microglia, and cortical neurons to 1800 MHz RF-EMF at 4.0 W/kg SAR to assess DNA damage and cellular functions. The authors report no significant induction of γH2AX foci and no significant changes in cytokine secretion or dendrite/synapse morphological…
Genotoxic Effects in Human Fibroblasts Exposed to Microwave Radiation.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human fetal and adult fibroblasts to 25 GHz microwave radiation and assessed multiple genotoxic and cellular endpoints. The authors report no evidence of direct DNA damage and no apoptosis or changes in prosurvival signalling proteins. However, they report increased total and…
The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study compared ginsenosides extracted using pulsed electric field (PEF) versus solvent cold soak extraction (SCSE). The abstract reports that PEF extracts had higher antioxidant capacity and provided greater protection against hydrogen peroxide-induced oxidative stress in HEK-293 cells, including…
RF-EMF exposure at 1800 MHz did not elicit DNA damage or abnormal cellular behaviors in different neurogenic cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study assessed whether intermittent 1800 MHz RF-EMF exposure induces DNA damage or alters cellular behavior in three neurogenic cell lines. Cells were exposed at an average SAR of 4.0 W/kg for 1, 6, or 24 hours and evaluated for γH2AX foci, cell cycle progression, proliferation, and viability. The…
Electromagnetic Field Assessment as a Smart City Service: The SmartSantander Use-Case.
Research
RF Safe Research Library
Jan 1, 2017
The study presents a smart city service for electromagnetic field assessment using deployed measuring probes integrated into a city platform. Data collected for more than one year are processed to characterize E-field levels across large areas and over time. The authors report that the results validate the…
Semi-quantitative proteomics of mammalian cells upon short-term exposure to non-ionizing electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study used proteome-wide semi-quantitative mass spectrometry to assess molecular changes after short-term exposure to ELF (50 Hz), UMTS (2.1 GHz), and WiFi (5.8 GHz) in human and mouse cell types. The authors report that fewer than 1% of quantified proteins changed slightly in abundance and that…
Calreticulin attenuated microwave radiation-induced human microvascular endothelial cell injury through promoting actin acetylation and polymerization.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human microvascular endothelial cells to high-power microwave radiation at multiple power densities for 6 minutes and assessed cellular injury and cytoskeletal outcomes. The authors report dose-dependent injury from microwave exposure, including increased LDH leakage and reduced viability…
Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation.
Research
RF Safe Research Library
Jan 1, 2017
This study investigated 2 nm protein-stabilized gold nanoclusters in six mammalian cell types under 1 GHz electromagnetic field exposure. The authors report low intrinsic toxicity of the nanoclusters, but a significant decrease in cell viability when nanocluster-incubated cells were exposed to the 1 GHz field,…