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A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury.

Research RF Safe Research Library Jan 1, 2023

This animal study used non-contact induction sensors and a shielded helmet to measure cortical EMF patterns in a Yucatan miniswine before and after traumatic brain injury induced by controlled cortical impact. The authors report that targeted low-frequency EMF stimulation initiated 20 minutes post-injury was…

Phagocytosis of latex beads by a human monocytic Mono Mac 6 cell line and effects of low-frequency electromagnetic field interaction.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested whether a low-frequency EMF (7 Hz, 30 mT) alters phagocytosis-related outcomes in the human monocytic Mono Mac 6 cell line. EMF exposure was associated with increased necrosis in cells pre-stimulated with SEB and then undergoing latex bead phagocytosis, while no significant cell-death…

P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…

Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line.

Research RF Safe Research Library Jan 1, 2023

This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…

Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).

Research RF Safe Research Library Jan 1, 2023

This in vitro study assessed 50 Hz, 100 G extremely low-frequency EMF in combination with temozolomide and radiation in T98 glioblastoma cells grown as monolayers and spheroids. Radiation plus EMF increased apoptosis-related gene expression, while temozolomide plus EMF increased autophagy marker expression compared…

Effects of repeated exposure to 50 Hz electromagnetic field on breast cancer cells.

Research RF Safe Research Library Jan 1, 2022

This in vitro study exposed two human breast cancer cell lines to a 50 Hz ELF-EMF (20 mT) for 3 hours/day for up to four days. The authors report reduced viability and apoptosis-related findings in MDA-MB-231 cells, with no significant viability change in MCF-7 cells. Cell-cycle effects differed by cell line,…

Protein expression changes during phagocytosis influenced by low-frequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2022

This in vitro study examined whether a low-frequency EMF (30 mT, 7 Hz for 3 h) alters phagocytosis of latex beads and immune-related protein/gene expression in the human Mono Mac 6 macrophage cell line. The authors report that EMF exposure influenced phagocytosis-associated molecular markers, with notable changes in…

Cardiac Cell Exposure to Electromagnetic Fields: Focus on Oxdative Stress and Apoptosis.

Research RF Safe Research Library Jan 1, 2022

This study assessed whether 915 MHz RF-EMF exposure alters oxidative stress and apoptosis markers in cardiac cells and mouse heart tissue. The authors report no statistically significant differences in apoptotic profile, antioxidant capacity, tissue integrity, or expression of apoptosis/antioxidant genes after…

Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.

Research RF Safe Research Library Jan 1, 2022

This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…

A New Treatment for Stretch Marks and Skin Ptosis with Electromagnetic Fields and Negative Pressure: A Clinical and Histological Study.

Research RF Safe Research Library Jan 1, 2021

This clinical and histological study evaluated a combined electromagnetic fields and negative pressure treatment (V-EMF) for stretch marks and skin hypotonia. Sixty women aged 25–45 underwent 6 or 8 weekly sessions, with documentation via pictures, patient satisfaction, and biopsies. The authors report histological…

The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…

Exposure to long-term evolution radiofrequency electromagnetic fields decreases neuroblastoma cell proliferation via Akt/mTOR-mediated cellular senescence.

Research RF Safe Research Library Jan 1, 2021

This in vitro study examined LTE RF-EMF exposure effects on SH-SY5Y neuroblastoma cells. The authors report reduced cell proliferation and a G0/G1 cell-cycle delay after 1760 MHz exposure at 4 W/kg for 4 hr/day over 4 days. They report no marked DNA damage signal (γH2AX) and no apoptosis activation, but increased…

Modern health worries and idiopathic environmental intolerance attributed to electromagnetic fields are associated with paranoid ideation.

Research RF Safe Research Library Jan 1, 2021

This cross-sectional online survey examined whether paranoid ideation is associated with modern health worries and idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF). Paranoid ideation was positively associated with modern health worries and with IEI-EMF status, even after controlling…

Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.

Research RF Safe Research Library Jan 1, 2021

This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…

Activation of matrix metalloproteinases and FoxO3a in HaCaT keratinocytes by radiofrequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed HaCaT human keratinocytes to 1760 MHz RF-EMF (SAR 4.0 W/kg; 2 h/day for 4 days). The authors report increased intracellular ROS and increased expression/activity of several matrix metalloproteinases, along with increased phosphorylation of FoxO3a and ERK1/2. Cell growth/viability and…

Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice.

Research RF Safe Research Library Jan 1, 2021

This animal study examined whether 8 weeks of EMF exposure affects insulin resistance and fatty liver features in db/db mice. The authors report improvements in insulin resistance markers, hepatic redox balance, and steatosis-related outcomes after EMF exposure. They also report reduced liver triglycerides and lower…

Effect of extremely low frequency electromagnetic field parameters on the proliferation of human breast cancer.

Research RF Safe Research Library Jan 1, 2021

This in vitro study tested how varying ELF-EMF parameters (frequency, flux density, duration, and continuous vs switching exposure) affect breast cancer and normal breast epithelial cell lines. The authors report that an optimized switching exposure pattern (7.83 ± 0.3 Hz, 1 mT) reduced viability of MDA-MB-231 cells…

Low-frequency electromagnetic field influences human oral mucosa keratinocyte viability in response to lipopolysaccharide or minocycline treatment in cell culture conditions.

Research RF Safe Research Library Jan 1, 2021

This in vitro study examined whether low-frequency electromagnetic field (LF-EMF) exposure affects viability of human oral mucosa keratinocytes. Apoptosis (early/late) and necrosis were measured by flow cytometry, including conditions with lipopolysaccharide (LPS) or minocycline. The authors report that LF-EMF, alone…

Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial cells.

Research RF Safe Research Library Jan 1, 2020

This in vitro study exposed murine microglial (N9) and human neuroblastoma (SH-SY5Y) cells to ELF-modulated 935 MHz RF-EMF at 4 W/kg for 2 or 24 hours. The authors report no changes in apoptosis, cell viability, or AIF across conditions. They report increased ATG5 after 24 hours and a transient glutathione increase…

Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice.

Research RF Safe Research Library Jan 1, 2020

This animal study exposed male BALB/c mice to 2100 MHz EMF and assessed reproductive and hormonal outcomes, including sperm parameters, testicular histology, HspA2 immunoreactivity, and apoptosis. EMF exposure was associated with increased testicular apoptosis, increased abnormal sperm, and increased HspA2…

Effect of Rehabilitation with Extremely Low Frequency Electromagnetic Field on Molecular Mechanism of Apoptosis in Post-Stroke Patients.

Research RF Safe Research Library Jan 1, 2020

This study evaluated whether adding extremely low frequency electromagnetic field (ELF-EMF) exposure to a rehabilitation program affects apoptosis-related gene expression in post-stroke patients. Forty-eight patients (3–4 weeks post-incident) were divided into ELF-EMF and non-ELF-EMF groups, with the ELF-EMF group…

Antimicrobial activity of rosemary leaf extracts and efficacy of ethanol extract against testicular damage caused by 50-Hz electromagnetic field in albino rats.

Research RF Safe Research Library Jan 1, 2020

This animal study exposed male albino rats to a 50 Hz electromagnetic field for 2 or 4 hours and assessed reproductive hormones, oxidative stress markers, and testicular histology after 30 days. The abstract reports that EMF exposure reduced serum FSH, testosterone, and LH and catalase activity, while increasing…

Osteoinductivity of polycaprolactone nanofibers grafted functionalized with carboxymethyl chitosan: Synergic effect of β-carotene and electromagnetic field.

Research RF Safe Research Library Jan 1, 2020

This in vitro study developed carboxymethyl chitosan (CMC)-grafted polycaprolactone (PCL) nanofiber scaffolds for bone tissue engineering. It reports mineralization and osteonectin expression in adipose mesenchymal stem cells cultured on the scaffolds, suggesting osteoinductive properties of the grafted CMC. The…

Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression.

Research RF Safe Research Library Jan 1, 2019

This study assessed pre-sowing sunflower seed treatments using vacuum, 5.28 MHz radio-frequency cold plasma, and an electromagnetic field for varying durations. The authors report faster germination with cold plasma (7 min) and EMF (15 min), while germination percentage was mostly unchanged except for a decrease…

Protective effects of luteolin on rat testis following exposure to 900 MHz electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This rat study examined 900 MHz EMF exposure effects on testes and whether luteolin modifies those effects. EMF exposure was associated with reduced testicular cell counts, lower testis weight and serum testosterone, increased SOD activity, and changes in sperm morphology versus controls. Luteolin co-treatment was…

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