Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice.
This animal study exposed male BALB/c mice to 2100 MHz EMF and assessed reproductive and hormonal outcomes, including sperm parameters, testicular histology, HspA2 immunoreactivity, and apoptosis. EMF exposure was associated with increased testicular apoptosis, increased abnormal sperm, and increased HspA2 immunoreactivity, alongside reduced sperm count, LH, and testosterone versus controls. Crocin co-treatment (50 mg/kg) was reported to significantly improve these EMF-associated changes compared with EMF exposure alone.
Key points
- Twenty-four male BALB/c mice were randomized into EMF, crocin, EMF+crocin, and control groups.
- The EMF exposure frequency was 2100 MHz, described as emitted from mobile phones.
- EMF exposure increased HspA2 immunoreactivity and germinal epithelium apoptosis compared with controls.
- EMF exposure increased abnormal sperm percentage and decreased sperm count compared with controls.
- LH and testosterone levels were decreased in the EMF group compared with controls, per the abstract.
- Crocin (50 mg/kg) co-treatment significantly improved several EMF-associated reproductive and hormonal changes compared with EMF alone.
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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