Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.
Endometrial slices exposed in vitro to 50 Hz ELF-EMF for 2 hours showed changes in DNMT1 and DNMT3a abundance, EZH2 mRNA and protein, EED and SUZ12 mRNA, global DNA methylation level, HDAC activity, and proteins involved in microRNA biogenesis. The authors co…