The effects of extremely low frequency electromagnetic fields exposure at 1 mT on hemogram and blood biochemistry in rats
Abstract
The effects of extremely low frequency electromagnetic fields exposure at 1 mT on hemogram and blood biochemistry in rats Jin Wang, Shenglan Yang, Xingfa Liu, Yemao Zhang, Lijian Ding, Xiong Wu, Mengying He, Guoran Ruan, Jinsheng Lai, Chen Chen. The effects of extremely low frequency electromagnetic fields exposure at 1 mT on hemogram and blood biochemistry in rats. Electromagn Biol Med. 2020 Oct 27;1-12. doi: 10.1080/15368378.2020.1839490. Abstract The biological effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure are not fully clarified. We conducted this investigation to explore the effects of ELF-EMF on hematologic and biochemical indexes in adult rats. Thirty adult male Sprague-Dawley rats were exposed to ELF-EMF at 1 mT for 24 weeks, while another 30 SD rats were sham exposed. During the exposure, peripheral blood was collected every 4 weeks to analyze the hematologic parameters and biochemical indexes. The morphology of liver and kidney was detected by hematoxylin-eosin staining at the end of the experiment. Exposed to ELF-EMF at 1 mT did not exert any statistic difference on hematologic parameters including total white blood cell count, neutrophil ratio, lymphocyte ratio, red blood cells, hemoglobin concentration and platelets count, compared to the control group. Similarly, biochemical indexes, such as glucose, lipid profile, liver function and renal function, were not affected by ELF-EMF exposure. In addition, no morphological change was observed in the liver and kidney from the exposure group. The exposure to ELF-EMF at the intensity of 1 mT for 24 weeks did not affect hematologic and biochemical indexes in adult rats. pubmed.ncbi.nlm.nih.gov
AI evidence extraction
Main findings
Thirty rats exposed to ELF-EMF at 1 mT for 24 weeks showed no statistically significant differences in measured hematologic parameters or biochemical indexes compared with 30 sham-exposed rats. No morphological changes were observed in liver or kidney at the end of the experiment.
Outcomes measured
- Hematologic parameters (total white blood cell count, neutrophil ratio, lymphocyte ratio, red blood cells, hemoglobin concentration, platelets count)
- Blood biochemical indexes (glucose, lipid profile, liver function, renal function)
- Liver morphology (H&E staining)
- Kidney morphology (H&E staining)
View raw extracted JSON
{
"study_type": "animal",
"exposure": {
"band": "ELF",
"source": null,
"frequency_mhz": null,
"sar_wkg": null,
"duration": "24 weeks"
},
"population": "Adult male Sprague-Dawley rats",
"sample_size": 60,
"outcomes": [
"Hematologic parameters (total white blood cell count, neutrophil ratio, lymphocyte ratio, red blood cells, hemoglobin concentration, platelets count)",
"Blood biochemical indexes (glucose, lipid profile, liver function, renal function)",
"Liver morphology (H&E staining)",
"Kidney morphology (H&E staining)"
],
"main_findings": "Thirty rats exposed to ELF-EMF at 1 mT for 24 weeks showed no statistically significant differences in measured hematologic parameters or biochemical indexes compared with 30 sham-exposed rats. No morphological changes were observed in liver or kidney at the end of the experiment.",
"effect_direction": "no_effect",
"limitations": [],
"evidence_strength": "low",
"confidence": 0.85999999999999998667732370449812151491641998291015625,
"peer_reviewed_likely": "yes",
"keywords": [
"extremely low frequency",
"ELF-EMF",
"1 mT",
"rats",
"Sprague-Dawley",
"hemogram",
"hematology",
"blood biochemistry",
"liver",
"kidney",
"H&E staining",
"sham exposure"
],
"suggested_hubs": []
}
AI can be wrong. Always verify against the paper.
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