Changes in miR-21, -138, -141, -135 expression and apoptosis/necrosis levels in HCT116 colon cancer cells under 50 Hz ELF-EMF exposure at 0.4 and 0.8 mT
Research
RF Safe Research Library
Feb 23, 2026
This in vitro study exposed HCT116 colorectal carcinoma cells to 50 Hz ELF-EMF at 0.4 or 0.8 mT for 9 or 18 hours under continuous or discontinuous conditions. The authors report significant changes in miR-21, miR-141, miR-135, and miR-138 expression and increased apoptosis and necrosis measured by flow cytometry.…
Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study examines a spinning oscillating magnetic field (sOMF) generated by an Oncomagnetic device and reports selective toxicity in glioma cancer cells. The abstract attributes effects to ROS-dependent inhibition of mitochondrial complex I, with downstream oxidative stress, DNA damage, cell-cycle arrest,…
Effects of electromagnetic fields from an alternating current power cable on the embryogenesis of three benthic associated marine species.
Research
RF Safe Research Library
Jan 1, 2026
A laboratory experiment exposed embryos of three benthic egg-laying marine species to realistic electromagnetic fields generated by an alternating-current subsea power cable set-up (magnetic field 4–6 μT). Subtle effects were reported for Scyliorhinus canicula and Loligo vulgaris, including faster growth and…
Female Crabs Are More Sensitive to Environmentally Relevant Electromagnetic Fields from Submarine Power Cables
Research
RF Safe Research Library
Jan 1, 2025
This controlled laboratory study examined sex-specific behavioral responses of juvenile shore crabs to magnetic fields intended to represent submarine power cable EMFs. Females showed consistent attraction to EMF-exposed zones across 500–3,200 μT exposures, whereas males showed no consistent spatial preference. The…
Analyzing the Impact of Occupational Exposures on Male Fertility Indicators: A Machine Learning Approach
Research
RF Safe Research Library
Jan 1, 2025
This occupational epidemiology study used machine learning to evaluate whether workplace exposures (including magnetic and electric fields, vibration, noise, and heat stress) predict male reproductive indicators in 80 workers. The models and explainable AI outputs highlighted magnetic and electric field exposures and…
Electromagnetic wireless remote control of mammalian transgene expression
Research
RF Safe Research Library
Jan 1, 2025
This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to…
Cardiac function in Vimba vimba embryos under electromagnetic exposure at hatchery-relevant intensities.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined 50 Hz electromagnetic exposure dominated by a measured magnetic component (~11.15 µT) on cardiac function in Vimba vimba embryos. Using two experimental series, the authors report significant increases in embryonic heart rate with EMF exposure during incubation and during observation. The…
Electromagnetic Field Influence on the Bioavailability and Accumulation of Ketoprofen.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro/ex vivo study tested whether different magnetic-field configurations alter ketoprofen properties and its transdermal delivery in porcine skin using Franz diffusion cells. The authors report no change in ketoprofen molecular structure, but subtle changes in crystal structure and physicochemical…
Effects of Electromagnetic Field on Seed Germination, β-Amylase Activity, Total Protein Content, Water Uptake, and Growth of Wheat Seedlings (Triticum aestivum).
Research
RF Safe Research Library
Jan 1, 2025
This laboratory study examined whether extremely low frequency EMF exposure affects wheat seed germination and early seedling development. Seeds exposed to 10 Hz, 7.5 mT EMF (5 h over 3 days) reportedly germinated earlier and showed higher biomass than untreated controls. The abstract also reports increased total…
Electromagnetic field-mediated chitosan/gelatin/nano-hydroxyapatite and bone-derived scaffolds regulate the osteoblastic and chondrogenic phenotypes of adipose-derived stem cells to construct osteochondral tissue engineering niche in vitro.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study examined how electromagnetic field (EMF) coupling parameters and field direction interact with 2D versus 3D culture environments to influence adipose-derived stem cell (ADSC) proliferation and osteogenic/chondrogenic differentiation. The abstract reports different “optimal” magnetic flux densities…
Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed three ccRCC cell lines and a healthy kidney cell line (HEK293) to 50 Hz ELF-EMF at 4.5 mT for 30 minutes daily over 5 days. The authors report exposure-associated changes in expression of several genes (names not fully visible in the abstract), with differences between primary…
Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed human osteosarcoma (MG-63) cells to 2 mT extremely low-frequency magnetic fields with sinusoidal, triangular, or pulsed waveforms under continuous (3 h) or fractionated (3 days) conditions. The authors report significant decreases in proliferation and shape index in exposed cells versus…
Effect of electromagnetic fields from renewable energy subsea power cables on righting reflex and physiological response of coastal invertebrates.
Research
RF Safe Research Library
Jan 1, 2023
This study examined whether electromagnetic fields (EMF) similar to those from offshore renewable subsea export cables affect coastal invertebrates. It simulated a 500 μT EMF and measured righting reflex and selected physiological markers in four species. The authors report no significant behavioural or physiological…
Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…
Optimization of cacao beans fermentation by native species and electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2023
This study optimized cacao bean fermentation for the CCN 51 clone using native microbial species and applied magnetic fields, varying field density, exposure time, and inoculum concentration. It reports improved yield and bean quality versus a no-magnetic-field control at an optimized condition (5 mT, 22.5 min, 1.6%…
Bidirectional Effect of Repeated Exposure to Extremely Low-Frequency Electromagnetic Field (50 Hz) of 1 and 7 mT on Oxidative/Antioxidative Status in Rat's Brain: The Prediction for the Vulnerability to Diseases.
Research
RF Safe Research Library
Jan 1, 2022
This rat study examined repeated 50 Hz ELF-EMF exposure (1 or 7 mT) and measured oxidative stress and antioxidant defense markers in the prefrontal cortex, including responses to a subsequent open-field stressor. The authors report intensity- and repetition-dependent effects: 1 mT produced weak changes and was…
Electromagnetic field affects the voltage-dependent potassium channel Kv1.3.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study tested whether extremely low-frequency electromagnetic fields (ELF-EMF) modulate the voltage-gated potassium channel Kv1.3 in Kv1.3-expressing CHO-K1 cells. Cells were exposed to a 20 Hz field at 268 µT or 902 µT while Kv1.3 currents were measured by whole-cell patch clamp. The authors report a…
Effects of 5-HT and 5-HT Receptor Agonists on Electromagnetic Field-Induced Analgesia in Rats.
Research
RF Safe Research Library
Jan 1, 2019
This animal study examined whether serotonergic signaling modifies analgesia associated with repeated ELF electromagnetic field exposure. Sixty-six male Wistar rats were exposed to 50 Hz, 5 mT for 2 hours/day over 15 days and then received 5-HT agonists or antagonists before analgesia testing. Agonists increased,…
Evaluation of the neuroprotective effects of electromagnetic fields and coenzyme Q on hippocampal injury in mouse.
Research
RF Safe Research Library
Jan 1, 2019
This animal study tested whether 50 Hz EMF exposure and/or CoQ10 could protect against TMT-induced hippocampal injury in mature female mice. CoQ10 and CoQ10+EMF were associated with improved spatial memory and reduced histological markers of cell death, alongside increased antiapoptotic markers. EMF alone reportedly…
Combined effects of electromagnetic field and low-level laser increase proliferation and alter the morphology of human adipose tissue-derived mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study tested 50 Hz, 3 mT electromagnetic field (EMF) exposure and 808 nm low-level laser (LLL), alone and combined, on human adipose tissue-derived mesenchymal stem cells from six donors. The authors report increased cell numbers after 7 days with EMF, greater increases with LLL, and the largest…
Research on in vitro release of Isoniazid (INH) super paramagnetic microspheres in different magnetic fields.
Research
RF Safe Research Library
Jan 1, 2016
This in vitro study examined how different external magnetic field conditions affect isoniazid release from superparamagnetic iron oxide microspheres. The abstract reports that magnetic fields accelerated drug release, with faster release in acidic (pH 3) conditions and the fastest completion (2 hours) under an…
Effects of extremely low frequency electromagnetic fields on in-vitro cellular cultures HeLa and CHO.
Research
RF Safe Research Library
Jan 1, 2016
This in-vitro study examined whether 50 Hz extremely low frequency electromagnetic fields affect proliferation in HeLa and CHO cell cultures. The abstract reports increased proliferation in exposed cells versus controls, with the largest reported increase under repetitive exposure at 2.49 mT (40 minutes every 12…
Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice
Research
RF Safe Research Library
May 5, 2015
This long-term animal study exposed mice to a 50 Hz magnetic field (500 mG) prenatally and then through 15.5 months of life to assess tumor-related outcomes and fertility-related measures. Exposed mice had lower body weights and showed no increase in liver or lung tumor incidence. However, exposed female mice had a…
Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat
Research
RF Safe Research Library
Aug 13, 2014
This randomized animal experiment examined whether 60 Hz extremely low frequency magnetic field (ELF-MF) exposure alters oxidative stress-related biomarkers in 75 Wistar rats. The authors report increased lipid peroxidation markers after both single and 14-day exposures, alongside changes in antioxidant-related…
The influence of low-frequency magnetic field on plasma antioxidant capacity and heart rate.
Research
RF Safe Research Library
Jan 1, 2009
This animal study exposed Sprague-Dawley rats to a 40 Hz, 7 mT time-variable magnetic field and measured ECG heart rate and plasma antioxidant capacity before and after exposure, including after 14 days. The authors report a significant decrease in heart rate after 14 days. Antioxidant defence findings were mixed,…