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Thermodynamic Considerations on the Biophysical Interaction between Low-Energy Electromagnetic Fields and Biosystems.

Research RF Safe Research Library Jan 1, 2024

This paper presents a thermodynamic model intended to explain how extremely low-frequency electromagnetic fields (ELF-EMFs) may interact with cells. The authors propose that ELF-EMFs directly interfere with the cellular membrane, producing biological responses linked to energy conversion and changes in flows across…

Anthropogenic electromagnetic radiation alters the transcription levels of the genes encoding the SIFamide and myoinhibitory peptide and their receptors in Ixodes ricinus synganglion.

Research RF Safe Research Library Jan 1, 2024

This animal study used qRT-PCR to assess whether 900 MHz radiofrequency electromagnetic field exposure alters neuropeptide-related gene transcription in Ixodes ricinus synganglia. The abstract reports that 40 V/m exposure for at least 60 minutes significantly suppressed transcript levels of sifa, mip, and their…

Improved assessment of radiofrequency electromagnetic field power deposition near orthopaedic device using a bone-inclusive ASTM phantom under 1.5T and 3T MRI.

Research RF Safe Research Library Jan 1, 2024

This engineering/simulation study proposes a bone-inclusive ASTM phantom to improve assessment of RF power deposition near orthopaedic implants during 1.5 T and 3 T MRI. Using numerical simulations across multiple implant families, the authors report better correlation of peak 1 g SAR near implants with anatomically…

Helmet Radio Frequency Phased Array Applicators Enhance Thermal Magnetic Resonance of Brain Tumors.

Research RF Safe Research Library Jan 1, 2024

This engineering study describes and simulates a helmet radio-frequency phased array applicator for Thermal Magnetic Resonance (ThermalMR), which combines MRI with targeted RF heating. Using EMF and temperature simulations in a phantom and human head model (including a modeled glioblastoma tumor volume), the authors…

Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring.

Research RF Safe Research Library Jan 1, 2024

This rat study examined prenatal stress, prenatal ELF-EMF exposure, and their combination on adult male offspring outcomes at postnatal day 90. Prenatal stress increased serum corticosterone but did not change spatial memory, while combined stress+ELF-EMF disrupted memory acquisition. ELF-EMF exposure was associated…

The exposure to extremely low frequency electromagnetic-fields inhibits the growth and potentiates the sensitivity to chemotherapy of bidimensional and tridimensional human osteosarcoma models.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested a specific extremely low frequency electromagnetic field (ELF-EMF) on three human osteosarcoma cell lines grown in 2D and 3D spheroid models. The abstract reports that ELF-EMF exposure inhibited proliferation and altered mitochondrial metabolism in the cancer models. It also reports…

The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…

Chronic Drug-Resistant Cystitis Treated with a Sequence of Modulated Extremely Low-Frequency Electromagnetic Fields: A Randomized Study of 148 Cases.

Research RF Safe Research Library Jan 1, 2024

This randomized placebo-controlled study evaluated sequenced, modulated extremely low-frequency electromagnetic fields for drug-resistant chronic bacterial cystitis in 148 women. The treated group showed significant between-group differences at 4 weeks in multiple laboratory parameters, with reported sustained…

Extremely low-frequency electromagnetic field (ELF-EMF) induced alterations in gene expression and cytokine secretion in clear cell renal carcinoma cells.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed three ccRCC cell lines and a healthy kidney cell line (HEK293) to 50 Hz ELF-EMF at 4.5 mT for 30 minutes daily over 5 days. The authors report exposure-associated changes in expression of several genes (names not fully visible in the abstract), with differences between primary…

Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices from days 15–16 of pregnancy to a 50 Hz extremely low-frequency electromagnetic field for 2 hours. The authors report changes in several epigenetic-related markers, including DNA methylation machinery, histone-related measures (HDAC activity), global DNA…

Variations of the spontaneous electrical activities of the neuronal networks imposed by the exposure of electromagnetic radiations using computational map-based modeling.

Research RF Safe Research Library Jan 1, 2023

This computational neuroscience study models a ring of three coupled Rulkov neurons to examine how electromagnetic induction may change spontaneous neuronal network activity. The abstract reports that magnetic field effects depend on the network’s initial dynamical regime and synaptic strength, including elimination…

Effect of soil pH on thermally enhanced desorption of m-xylene by zero-valent iron particles under an electromagnetic field.

Research RF Safe Research Library Jan 1, 2023

This laboratory/engineering study evaluated thermally enhanced desorption of m-xylene from soil using heat generated by zero-valent iron (ZVI) under low-frequency electromagnetic fields. The abstract reports rapid heating (to ~60°C in 20 minutes) and substantially lower residual m-xylene after 60 minutes versus soil…

CaATPase enzyme activities and lipid and protein oxidations of grass carp (Ctenopharyngodon idellus) stored at 4 °C for 30 min under electromagnetic fields.

Research RF Safe Research Library Jan 1, 2023

This study evaluated 12 mT electromagnetic fields (100–400 Hz) applied during 30 minutes of cold storage (4 °C) of grass carp. EMF exposure was associated with increased CaATPase activity and frequency-dependent changes in protein and lipid oxidation. NMR results suggested altered water–protein interactions, and the…

Effects of 2.4 GHz radiofrequency electromagnetic field (RF-EMF) on glioblastoma cells (U -118 MG).

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed glioblastoma (U-118 MG) and human embryonic kidney (Hek-293) cells to 2.4 GHz RF-EMF for 24–72 hours, with or without a dielectric screen. The authors report a significant decrease in cell viability after exposure in both cell lines. The decrease was described as greater in glioblastoma…

Comment on Redmayne, M.; Maisch, D.R. ICNIRP Guidelines' Exposure Assessment Method for 5G Millimetre Wave Radiation May Trigger Adverse Effects. 2023, , 5267.

Research RF Safe Research Library Jan 1, 2023

This commentary critiques a prior paper claiming that Brillouin precursors from 5G NR and other cellular systems could cause tissue damage deeper than the carrier-frequency penetration depth. It states that the original Brillouin precursor theory was based on nanosecond ultrawide-band RF pulses in water and that this…

The Use of Induction Sensors and Helmet-Based Shielding Technology to Identify Differences in Electromagnetic Fields in Patients With Cranial Neurological Disease Versus Healthy Controls.

Research RF Safe Research Library Jan 1, 2023

This observational study used induction sensors with a Mu-metal and copper mesh shielded helmet to measure cortically generated EMFs in patients with cranial neurological disease and compare patterns to previously obtained healthy control data. Fourteen patients (ages 14–81) were analyzed and compared with four…

NET Formation Was Reduced via Exposure to Extremely Low-Frequency Pulsed Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2023

This in vitro study examined whether a 16 Hz extremely low-frequency pulsed electromagnetic field (ELF-PEMF) affects neutrophil extracellular trap (NET) formation. In neutrophils from healthy volunteers, ELF-PEMF exposure did not induce ROS or calcium influx and did not increase basal or PMA-induced NET formation.…

The Effect of Low-Frequency Pulsed Electromagnetic Fields on the Differentiation of Permanent Dental Pulp Stem Cells into Odontoblasts.

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed dental pulp mesenchymal stem cells to 50 Hz pulsed electromagnetic fields at 0.5 or 1 mT for 20 or 40 minutes per day over seven days. Cell survival/proliferation was generally higher than control across exposure groups, except for the 40 minutes/day at 1 mT condition. DMP1 expression was…

Human osteosarcoma cells in response to ELF-MF: Morphological remodeling compared to cell proliferation.

Research RF Safe Research Library Jan 1, 2023

This in vitro study exposed human osteosarcoma (MG-63) cells to 2 mT extremely low-frequency magnetic fields with sinusoidal, triangular, or pulsed waveforms under continuous (3 h) or fractionated (3 days) conditions. The authors report significant decreases in proliferation and shape index in exposed cells versus…

A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury.

Research RF Safe Research Library Jan 1, 2023

This animal study used non-contact induction sensors and a shielded helmet to measure cortical EMF patterns in a Yucatan miniswine before and after traumatic brain injury induced by controlled cortical impact. The authors report that targeted low-frequency EMF stimulation initiated 20 minutes post-injury was…

Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France.

Research RF Safe Research Library Jan 1, 2023

This study conducted personal full-shift RF-EMF measurements in 333 workers across 46 occupations in Spain and France. Most 1-second measurements of electric and magnetic fields were below the device detection limit (≥1% of 1998 ICNIRP standards), though many workers had at least one detectable reading. A small…

The Effect of Extremely Low-Frequency Electromagnetic Fields on Inflammation and Performance-Related Indices in Trained Athletes: A Double-Blinded Crossover Study.

Research RF Safe Research Library Jan 1, 2023

This double-blinded crossover study tested an ELF-EMF mattress used immediately after high-intensity cycling and overnight in nine trained male athletes. The authors report no significant overall effects on performance and inflammation. However, between 60 minutes and 24 hours post-exercise, the active condition…

A Novel and Versatile Microfluidic Device for Cell Assays under Radio Frequency Exposure.

Research RF Safe Research Library Jan 1, 2023

This in vitro study describes a microfluidic device integrated with a radiofrequency exposure system to enable on-chip monitoring of cellular responses under a 1.8 GHz field. Using human amniotic epithelial cells, the authors report field-intensity-associated increases in protrusions/filopodia, changes in…

It is the Frequency that Matters: Effects of Electromagnetic Fields on the Release and Content of Extracellular Vesicles.

Research RF Safe Research Library Jan 1, 2023

This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…

A Swine Model of Changes in the Neuronal Electromagnetic Field After Traumatic Brain Injury: A Pilot Study.

Research RF Safe Research Library Jan 1, 2023

This pilot swine study evaluated whether non-contact proprietary induction sensors in a Mu-metal/copper mesh helmet can measure endogenous neuronal EMF signals before and after controlled cortical impact traumatic brain injury. The authors report that swine EMF recordings were distinguishable from room noise and…

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