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2.45 GHz microwave radiation induced oxidative and nitrosative stress mediated testicular apoptosis: Involvement of a p53 dependent bax-caspase-3 mediated pathway.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed 12-week-old male mice to 2.45 GHz continuous-wave microwave radiation (average power density 0.0248 mW/cm; whole-body SAR 0.0146 W/kg) for 2 hours/day over 15, 30, or 60 days. The authors evaluated testicular histology, testosterone, oxidative/nitrosative stress markers, antioxidant enzymes,…

Oxidative and mutagenic effects of low intensity GSM 1800 MHz microwave radiation

Research RF Safe Research Library Jan 1, 2018

This animal study used developing quail embryos to assess oxidative and mutagenic effects of low-intensity GSM 1800 MHz radiation from a commercial smartphone. The authors report statistically significant increases in oxidative stress markers, DNA integrity damage, and oxidative DNA damage (8-oxo-dG) in exposed…

The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells.

Research RF Safe Research Library Jan 1, 2017

This in vitro study compared ginsenosides extracted using pulsed electric field (PEF) versus solvent cold soak extraction (SCSE). The abstract reports that PEF extracts had higher antioxidant capacity and provided greater protection against hydrogen peroxide-induced oxidative stress in HEK-293 cells, including…

Lasting hepatotoxic effects of prenatal mobile phone exposure.

Research RF Safe Research Library Jan 1, 2017

This animal study examined liver outcomes in rat offspring 60 days after prenatal exposure to a 900 MHz electromagnetic field for 24 hours/day during gestation. The exposed group showed biochemical changes consistent with oxidative stress (higher MDA, lower GSH) and elevated liver enzymes (ALT, AST). Histopathology…

Effect of extremely low-frequency electromagnetic fields on antioxidant activity in the human keratinocyte cell line NCTC 2544.

Research RF Safe Research Library Jan 1, 2017

This in vitro study exposed human keratinocyte cells (NCTC 2544) to 50 Hz ELF-EMF at 0.25–2 G and assessed oxidative stress-related endpoints. Significant increases in ROS were reported at 0.5 and 1 G, with associated short-term changes in antioxidant and lipid peroxidation markers. The authors report that…

Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.

Research RF Safe Research Library Jan 1, 2017

This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…

Cytotoxicity of temozolomide on human glioblastoma cells is enhanced by the concomitant exposure to an extremely low-frequency electromagnetic field (100Hz, 100G).

Research RF Safe Research Library Jan 1, 2017

This in vitro study tested whether an extremely low-frequency EMF (100 Hz, 100 G) could enhance temozolomide cytotoxicity in human glioma cell lines (U87 and T98G). The authors report that combined EMF and temozolomide increased apoptosis relative to either treatment alone and was accompanied by changes in…

Extremely low frequency electromagnetic field (ELF-EMF) reduces oxidative stress and improves functional and psychological status in ischemic stroke patients.

Research RF Safe Research Library Jan 1, 2017

This clinical study evaluated whether adding ELF-EMF exposure to a 4-week rehabilitation program affects antioxidant and clinical status in ischemic stroke patients. Fifty-seven patients were assigned to an ELF-EMF group or a non-ELF-EMF group, with the exposed group receiving 40 Hz, 7 mT for 15 minutes per day over…

The influence of prenatal 10 GHz microwave radiation exposure on a developing mice brain.

Research RF Safe Research Library Jan 1, 2017

This animal study examined prenatal exposure to 10 GHz microwave radiation starting at gestation day 0.25 or 11.25 until term. At 3 weeks of age, offspring from exposed pregnancies showed reduced brain and body weight and biochemical changes consistent with oxidative stress compared with sham controls. The authors…

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.

Research RF Safe Research Library Jan 1, 2017

This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…

The Synergistic Effect of Microwave Radiation and Hypergravity on Rats and the Intervention Effect of Rana Sylvatica Le Conte Oil.

Research RF Safe Research Library Jan 1, 2017

This animal study examined combined exposure to microwave radiation and hypergravity in rats and assessed whether Rana sylvatica Le Conte oil had protective effects. The hypergravity plus microwave group showed reduced motor performance, reduced cholinergic enzyme activities, and reduced total antioxidant capacity,…

Radiation from wireless technology elevates blood glucose and body temperature in 40-year-old type 1 diabetic male.

Research RF Safe Research Library Jan 1, 2017

This case report describes a 40-year-old male with type 1 diabetes who reported repeated episodes of markedly elevated blood glucose associated with nearby microwave radiation from wireless technology, with decreases after exposure ended. In one episode, body temperature also increased, and both measures reportedly…

[Protective effects of Genistein on human renal tubular epithelial cells damage of microwave radiation].

Research RF Safe Research Library Jan 1, 2017

This in vitro study exposed human proximal renal tubular epithelial cells (HKC) to microwave irradiation for 24 hours and assessed cell injury, oxidative stress, and cell death. The authors report increased injury markers (LDH, NAG), increased oxidative stress (higher MDA, lower SOD), and more apoptosis/necrosis…

Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor

Research RF Safe Research Library Jan 1, 2016

This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are…

Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression

Research RF Safe Research Library Jan 1, 2016

This 2016 narrative review proposes that non-thermal microwave/lower-frequency EMFs act primarily through activation of voltage-gated calcium channels (VGCCs), with calcium channel blockers reported to block EMF effects. It summarizes animal, occupational, and epidemiological literature and reports that exposures…

Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.

Research RF Safe Research Library Jan 1, 2016

This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…

2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism

Research RF Safe Research Library Jan 1, 2015

This animal study exposed male Swiss mice to 2.45 GHz continuous-wave microwave radiation for 2 hours/day over 15, 30, or 60 days. The authors report increased hippocampal oxidative/nitrosative stress and increased apoptosis in neuronal and nonneuronal hippocampal subfields. They also report duration-dependent…

A cross-sectional study on oxidative stress in workers exposed to extremely low frequency electromagnetic fields

Research RF Safe Research Library Jan 1, 2015

This cross-sectional study compared oxidative stress and genotoxicity biomarkers between 310 ELF-EMF-exposed inspection workers and 300 logistical staff controls. The authors report no statistically significant differences in antioxidant-related measures (T-AOC, GPx, SOD) or MDA, and no significant differences in…

Impacts of exposure to 900 MHz mobile phone radiation on liver function in rats.

Research RF Safe Research Library Jan 1, 2015

This animal experiment randomized 20 male Sprague-Dawley rats to 900 MHz electromagnetic radiation exposure (4 h/day for 18 days) or no exposure. The exposed group showed increased oxidative stress markers in liver tissue (higher MDA, lower GSH) and reported histopathological changes, along with increased apoptosis…

The effect of electromagnetic radiation emitted by display screens on cell oxygen metabolism - in vitro studies.

Research RF Safe Research Library Jan 1, 2015

This in vitro study exposed human blood platelet suspensions to 1 kHz electromagnetic fields at 150 or 220 V/m for 30 or 60 minutes. The authors report increased ROS and MDA (at 220 V/m, 30 min) and decreased antioxidant enzyme activities (SOD-1 and catalase), with the largest changes at 220 V/m for 60 minutes. They…

Effects of extremely low frequency electromagnetic fields on paraoxonase serum activity and lipid peroxidation metabolites in rat

Research RF Safe Research Library Aug 13, 2014

This randomized animal experiment examined whether 60 Hz extremely low frequency magnetic field (ELF-MF) exposure alters oxidative stress-related biomarkers in 75 Wistar rats. The authors report increased lipid peroxidation markers after both single and 14-day exposures, alongside changes in antioxidant-related…

2.45-GHz microwave irradiation adversely affects reproductive function in male mouse, Mus musculus by inducing oxidative and nitrosative stress

Research RF Safe Research Library Jan 1, 2014

This animal study exposed 12-week-old male Swiss strain mice to non-thermal low-level 2.45-GHz microwave radiation for 2 hours per day over 30 days (SAR 0.018 W/kg). The abstract reports reduced sperm count and viability, testicular structural changes, lower 3β-HSD activity and plasma testosterone, and increased…

Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats

Research RF Safe Research Library Jan 1, 2014

This animal study examined 2.45 GHz Wi-Fi exposure in a PTZ-induced epilepsy rat model using freshly isolated hippocampal and DRG neurons. The authors report that epilepsy increased Ca(2+) influx, oxidative stress markers, and apoptosis-related outcomes, and that Wi-Fi exposure produced additional increases in…

Effect of mobile phone usage time on total antioxidant capacity of saliva and salivary immunoglobulin a.

Research RF Safe Research Library Jan 1, 2014

This cross-sectional study assessed whether daily mobile phone usage time is associated with salivary total antioxidant capacity in 105 volunteers. Participants were divided into three groups by usage, and total antioxidant capacity was measured using the FRAP method. The study reports a statistically significant…

Spatial learning, monoamines and oxidative stress in rats exposed to 900 MHz electromagnetic field in combination with iron overload.

Research RF Safe Research Library Jan 1, 2014

This animal study tested whether 900 MHz EMF exposure, alone or combined with brain iron overload, affects cognition and brain biochemistry in Long-Evans rats. EMF-exposed rats showed impairment in an object exploration task and changes in monoamine content (notably in the hippocampus), while other spatial…

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