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Hazardous effects of high voltage electromagnetic field on albino rats and protective role of Rosmarinus officinalis.

Research RF Safe Research Library Jan 1, 2022

This animal study examined effects of a 50 Hz high-voltage electromagnetic field (5.4 kV/m) applied 2 or 4 hours per day for 25 days in albino rats. The authors report decreases in RBC, haemoglobin, and catalase activity, with increases in WBCs, liver enzymes, bilirubin, kidney-related markers, and malondialdehyde…

Cardiac Cell Exposure to Electromagnetic Fields: Focus on Oxdative Stress and Apoptosis.

Research RF Safe Research Library Jan 1, 2022

This study assessed whether 915 MHz RF-EMF exposure alters oxidative stress and apoptosis markers in cardiac cells and mouse heart tissue. The authors report no statistically significant differences in apoptotic profile, antioxidant capacity, tissue integrity, or expression of apoptosis/antioxidant genes after…

Changes in Free Radical Processes under the Influence of Low-Frequency Electromagnetic Field in Rats.

Research RF Safe Research Library Jan 1, 2022

This in vivo animal study examined how low-frequency electromagnetic field exposure affects antioxidant status in Wistar rats. The authors report frequency-dependent changes in antioxidant enzyme activity and hydroperoxide content in blood plasma. They also propose that LF EMF may stimulate low levels of ROS that…

Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study.

Research RF Safe Research Library Jan 1, 2022

This in vitro study evaluated short-term extremely low frequency electromagnetic field (ELF-EMF) exposure and silver nanoparticles (AgNPs), alone and combined, for antibacterial effects and apoptosis induction in MCF-7 breast cancer cells. The authors report time-dependent reductions in bacterial viable counts, with…

Prioritizing health outcomes when assessing the effects of exposure to radiofrequency electromagnetic fields: A survey among experts.

Research RF Safe Research Library Jan 1, 2021

This paper reports a survey designed to prioritize which RF EMF-related health outcomes should be addressed in systematic reviews. Of 300 experts queried, 164 responded and rated cancer, heat-related effects, adverse birth/pregnancy outcomes, electromagnetic hypersensitivity, cognitive impairment, and oxidative…

Conformational changes of β-thalassemia major hemoglobin and oxidative status of plasma after in vitro exposure to extremely low-frequency electromagnetic fields: An artificial neural network analysis.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed blood samples from β-thalassemia major patients and matched healthy donors (n=12 each) to 50 Hz ELF-EMF at 0.5 and 1 mT for 1–2 hours. The authors report that two-hour exposure induced significant oxidative changes in β-thalassemia major samples and examined protein/Hb structural features…

Comparing the Effects of Long-term Exposure to Extremely Low-frequency Electromagnetic Fields With Different Values on Learning, Memory, Anxiety, and β-amyloid Deposition in Adult Rats.

Research RF Safe Research Library Jan 1, 2021

This animal study exposed adult male rats to 50 Hz ELF-EMF at 1, 100, 500, or 2000 μT for 1 hour/day over two months and assessed behavior and brain markers. The authors report increased memory retention (higher step-through latency) alongside increased anxiety-like behavior (reduced open-arm entries), particularly…

Effects induced by a 50 Hz electromagnetic field and doxorubicin on Walker-256 carcinosarcoma growth and hepatic redox state in rats.

Research RF Safe Research Library Jan 1, 2021

This animal study compared 50 Hz extremely low-frequency EMF exposure with doxorubicin (and their combination) in Walker-256 carcinosarcoma-bearing rats, assessing tumor growth and liver redox-related outcomes. DOX and DOX+EMF were reported to inhibit tumor growth more than EMF alone, though EMF alone also showed an…

The guardians of germ cells; Sertoli-derived exosomes against electromagnetic field-induced oxidative stress in mouse spermatogonial stem cells.

Research RF Safe Research Library Jan 1, 2021

This in vitro study exposed mouse spermatogonial stem cells to 50 Hz EMF (2.5 mT; 1 h/day for 5 days) and assessed oxidative stress and cell health outcomes. The authors report increased ROS and apoptosis with reduced antioxidant (catalase) expression, viability, and colonization after EMF exposure. Sertoli…

Evaluation of the neuroprotective effects of Vitamin E on the rat substantia nigra neural cells exposed to electromagnetic field: An ultrastructural study.

Research RF Safe Research Library Jan 1, 2021

This rat study exposed animals to a 50 Hz, 3 mT electromagnetic field and assessed oxidative stress markers and substantia nigra ultrastructure. EMF exposure was associated with higher lipid peroxidation (MDA), lower SOD activity, and TEM-detected changes in nucleus/nuclear membrane and myelin sheath. Vitamin E…

Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice.

Research RF Safe Research Library Jan 1, 2021

This animal study examined whether 8 weeks of EMF exposure affects insulin resistance and fatty liver features in db/db mice. The authors report improvements in insulin resistance markers, hepatic redox balance, and steatosis-related outcomes after EMF exposure. They also report reduced liver triglycerides and lower…

Enhancement in the ATP level and antioxidant capacity of under continuous exposure to extremely low-frequency electromagnetic field for multiple generations.

Research RF Safe Research Library Jan 1, 2020

This multi-generation animal study exposed worms continuously to 50 Hz, 3 mT extremely low-frequency electromagnetic fields and assessed outcomes in the 15th generation. The study reports increased body length, higher ATP content and ATP synthase activity, and upregulated ATP-related gene expression in exposed worms.…

Assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations.

Research RF Safe Research Library Jan 1, 2020

This animal study evaluated liver function, histopathology, and oxidative stress markers after exposure to RF-EMF (900/1800 MHz and 2.4 GHz), x-rays (10 cGy or 8 Gy), and combinations including RF-EMF pre-exposure. Some liver enzymes (AST, ALT, ALP) showed some association with irradiation, while…

Effects of pulse-modulated radiofrequency magnetic field (RF-EMF) exposure on apoptosis, autophagy, oxidative stress and electron chain transport function in human neuroblastoma and murine microglial cells.

Research RF Safe Research Library Jan 1, 2020

This in vitro study exposed murine microglial (N9) and human neuroblastoma (SH-SY5Y) cells to ELF-modulated 935 MHz RF-EMF at 4 W/kg for 2 or 24 hours. The authors report no changes in apoptosis, cell viability, or AIF across conditions. They report increased ATG5 after 24 hours and a transient glutathione increase…

Antimicrobial activity of rosemary leaf extracts and efficacy of ethanol extract against testicular damage caused by 50-Hz electromagnetic field in albino rats.

Research RF Safe Research Library Jan 1, 2020

This animal study exposed male albino rats to a 50 Hz electromagnetic field for 2 or 4 hours and assessed reproductive hormones, oxidative stress markers, and testicular histology after 30 days. The abstract reports that EMF exposure reduced serum FSH, testosterone, and LH and catalase activity, while increasing…

Impact of extremely low-frequency electromagnetic field (100 Hz, 100 G) exposure on human glioblastoma U87 cells during Temozolomide administration.

Research RF Safe Research Library Jan 1, 2019

This in vitro study evaluated whether extremely low-frequency EMF exposure (100 Hz, 100 G) modifies the effects of temozolomide (100 µM) in human glioblastoma U87 cells over 120–144 hours. The authors report that combined treatment reduced stemness-associated markers (Nestin, CD133, Notch4) and increased GFAP…

Altered morphology and biochemistry of the female rat liver following 900 megahertz electromagnetic field exposure during mid to late adolescence.

Research RF Safe Research Library Jan 1, 2019

This animal study examined whether 900 MHz EMF exposure during mid to late adolescence affects the liver in female rats. Compared with control and sham groups, the exposed group showed occasional liver histopathological irregularities. The exposed group also had significantly decreased 8-OHdG and SOD levels, and the…

Protective effects of luteolin on rat testis following exposure to 900 MHz electromagnetic field.

Research RF Safe Research Library Jan 1, 2019

This rat study examined 900 MHz EMF exposure effects on testes and whether luteolin modifies those effects. EMF exposure was associated with reduced testicular cell counts, lower testis weight and serum testosterone, increased SOD activity, and changes in sperm morphology versus controls. Luteolin co-treatment was…

Modulation of antioxidant enzyme gene expression by extremely low frequency electromagnetic field in post-stroke patients.

Research RF Safe Research Library Jan 1, 2018

This study evaluated whether adding extremely low frequency electromagnetic field (ELF-EMF) therapy to standard physical therapy modulates antioxidant gene expression in post-stroke patients. Forty-eight patients were split into an ELF-EMF group and a non-ELF-EMF group, with both groups receiving the same physical…

Low frequency electromagnetic field decreases ischemia-reperfusion injury of human cardiomyocytes and supports their metabolic function.

Research RF Safe Research Library Jan 1, 2018

This in vitro study tested whether extremely low frequency/low frequency electromagnetic field (LF-EMF) exposure modifies ischemia-reperfusion injury in human cardiac-related cell types. Using LDH and MMP-2 activities and fluorescein diacetate staining, the authors report that short courses of LF-EMF reduced cellular…

Electromagnetic field exposure (50 Hz) impairs response to noxious heat in American cockroach.

Research RF Safe Research Library Jan 1, 2018

This animal study examined whether 50 Hz electromagnetic field exposure (7 mT) affects heat-escape behavior and oxidative balance in American cockroaches. The authors report increased latency to escape from noxious heat after 24 h, 72 h, and 7 days of exposure. Biomarkers suggested oxidative stress, with elevated…

Selenium supplementation ameliorates electromagnetic field-induced oxidative stress in the HEK293 cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study examined whether selenium supplementation modifies oxidative stress and apoptosis markers in HEK293 cells exposed to 2.4 GHz EMF. The authors report that EMF exposure increased lipid peroxidation (MDA) and apoptosis-related markers while decreasing antioxidant enzyme activities and bcl-2 versus…

Electromagnetic Field Could Protect SH-SY5Y Cells Against Cisplatin Cytotoxicity, But Not MCF-7 Cells.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed MCF-7 and SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field in combination with cisplatin and/or morphine. The combined "CDDP+Mor+EMF" condition showed higher cisplatin IC values than cisplatin alone and "CDDP+Mor" in both cell lines, consistent with reduced cisplatin cytotoxicity.…

Continuous 900-megahertz electromagnetic field applied in middle and late-adolescence causes qualitative and quantitative changes in the ovarian morphology, tissue and blood biochemistry of the rat.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed adolescent female rats to a 900-MHz electromagnetic field for 1 hour per day from postnatal days 35 to 59 and assessed ovarian histology and biochemical markers. The EMF group showed multiple histopathological changes in ovarian tissue and had fewer secondary follicles than the other groups.…

Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.

Research RF Safe Research Library Jan 1, 2018

This animal study examined 2.45 GHz microwave exposure in male Swiss albino mice for 2 hours per day over 30 days. The authors report increased oxidative stress markers and reduced antioxidant enzymes and testosterone in exposed mice versus sham controls. They also report micronuclei formation in blood and…

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