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Electromagnetic fields modulate neuronal membrane ionic currents through altered cellular calcium homeostasis.

Research RF Safe Research Library Jan 1, 2025

This experimental study used loose patch clamp recordings in coronal hippocampal slices to test effects of extremely low-frequency EMF exposure. A 50 Hz, 1 mT field applied for 60 minutes decreased inward and transient outward currents in CA1 pyramidal neuron membranes. Pharmacological manipulation of intracellular…

Sinusoidal Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Promotes Angiogenesis In Vitro.

Research RF Safe Research Library Jan 1, 2025

This in vitro/in ovo study examined whether extremely low-frequency electromagnetic stimulation (ELF-EMS; 13.5 mT at 10 and 60 Hz) activates angiogenic processes under homeostatic conditions. In human microvascular endothelial cells, ELF-EMS increased proliferation, migration/transmigration, and tube formation, with…

Impact of various electromagnetic fields on the transdermal permeability of naproxen and the effect of active compound exposure on magnetic field properties.

Research RF Safe Research Library Jan 1, 2025

This ex vivo study tested whether different magnetic-field modalities change transdermal delivery of naproxen through pigskin. Rotating magnetic fields (RMF) at 50 Hz produced the greatest increase in permeation metrics versus a no-EMF control, while negatively polarized static fields reduced permeation.…

Performance Evaluation and Calibration of Electromagnetic Field (EMF) Area Monitors Using a Multi-Wire Transverse Electromagnetic (MWTEM) Transmission Line.

Research RF Safe Research Library Jan 1, 2025

This engineering study evaluates and calibrates an EMF area monitor for the 300 kHz–20 MHz frequency band using a multi-wire transverse electromagnetic (MWTEM) transmission line as a controlled electric-field source. The authors highlight that low-frequency electric-field measurements can be sensitive to boundary…

Electric and Magnetic Field Technologies in Agriculture: Plant Responses, Experimental Limitations, and Future Directions

Research RF Safe Research Library Jan 1, 2024

This narrative review discusses how electric and magnetic field technologies are applied in agriculture and how plants may respond. It proposes a model to explain potential mechanistic convergence between electric and magnetic field effects. The review highlights several suggested mechanisms, including membrane…

Prospective cohort study on non-specific symptoms, cognitive, behavioral, sleep and mental health in relation to electronic media use and transportation noise among adolescents (HERMES): study protocol

Research RF Safe Research Library Jan 1, 2024

This protocol describes the third wave of the HERMES prospective adolescent cohort in Switzerland, with follow-up every four months and at one year. The study will assess electronic media use, modeled RF-EMF and transportation noise exposures, and a range of outcomes including cognition, behavior, sleep, mental…

Effect of Repeated Exposure to Complexly Organized Electromagnetic Radiation on the Rat Behavior in the "Open Field" Test

Research RF Safe Research Library Jan 1, 2024

This animal study examined repeated pulsed-modulated RF exposure (1–4 GHz; total pulse power density 300 μW/cm2) in male and female Wistar rats and assessed behavior using the open field test. The abstract reports stress reactions and long-term memory impairment in some rats, with females described as more sensitive…

Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD and CD erythroid like progenitor.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested whether daily exposure to a 10 mT ELF electromagnetic field, combined with miR-16 and miR-451 transfection, could enhance trans-differentiation of human dermal fibroblasts toward erythroid-like progenitors. The authors report increased erythroid-like differentiation with ELF-EMF exposure,…

Transcriptional response of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed rat primary hippocampal neurons to 3.0 GHz continuous-wave RF-EMF under low-SAR (minimal heating) and high-SAR (thermal) conditions and measured transcriptional responses by RNA sequencing. Twenty genes were significantly upregulated only in the high-SAR condition associated with a ~3.6°C…

Impact of Extremely Low-Frequency Electromagnetic Fields on Skeletal Muscle of Sedentary Adult Mice: A Pilot Study.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study examined ELF-EMF exposure (0.1 or 1.0 mT, 1 h/day up to 5 weeks) in sedentary adult male C57BL/6 mice, with or without N-acetyl-cysteine (NAC) supplementation. The authors report a transient increase in muscle strength after 2 weeks at 1.0 mT, accompanied by higher PAX7 and myosin heavy chain…

Crosstalk between 6-methyladenine and 4-methylcytosine in exposed to extremely low-frequency electromagnetic field.

Research RF Safe Research Library Jan 1, 2024

This study examined prokaryotic DNA methylation (6mA and 4mC) and transcriptomes under different intensities of extremely low-frequency electromagnetic field (ELF-EMF) exposure. It reports motif-specific 6mA at 5'-GTACAG-3' and ELF-EMF-intensity-associated changes in spatial relationships among other 6mA sites,…

Anthropogenic electromagnetic radiation alters the transcription levels of the genes encoding the SIFamide and myoinhibitory peptide and their receptors in Ixodes ricinus synganglion.

Research RF Safe Research Library Jan 1, 2024

This animal study used qRT-PCR to assess whether 900 MHz radiofrequency electromagnetic field exposure alters neuropeptide-related gene transcription in Ixodes ricinus synganglia. The abstract reports that 40 V/m exposure for at least 60 minutes significantly suppressed transcript levels of sifa, mip, and their…

The Extremely-Low-Frequency Electromagnetic Field Affects Apoptosis and Oxidative-Stress-Related Genes and Proteins in the Porcine Endometrium-An In Vitro Study.

Research RF Safe Research Library Jan 1, 2024

This in vitro study exposed porcine endometrial slices collected during the peri-implantation period to a 50 Hz extremely-low-frequency electromagnetic field for 2 hours. The authors report decreased CASP7 and increased NOS3/eNOS mRNA and protein abundance after exposure, along with increases in additional…

The impact of electromagnetic fields generated by high-voltage power lines on the spatial arrangement of pike (Esox Lucius Linnaeus 1758) embryos.

Research RF Safe Research Library Jan 1, 2024

This animal study incubated fertilized pike eggs under electromagnetic fields associated with high-voltage transmission lines (110 kV and 220 kV) and compared them with a control group without anthropogenic EMF. The authors report no significant effect of HVTL-related EMF on embryo orientation and conclude survival…

In Situ Assessment of Uplink Duty Cycles for 4G and 5G Wireless Communications.

Research RF Safe Research Library Jan 1, 2024

This exposure assessment measured in situ smartphone uplink duty cycles for 4G LTE and 5G NR across six voice, video, and data use cases. Measurements were taken at ten positions near a 4G and 5G base-station site in Belgium. Reported duty cycles varied by application, with some use cases showing low-to-moderate duty…

Electromagnetic Field Stimulation Therapy for Alzheimer's Disease.

Research RF Safe Research Library Jan 1, 2024

This review discusses repeated electromagnetic field stimulation (REMFS) as a potential non-invasive therapy for Alzheimer's disease. The abstract describes reported benefits in AD mice, including reduced beta-amyloid, prevention of neuronal death, halted disease progression, and improved memory without edema or…

Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study used a Yucatan miniswine model of traumatic brain injury with and without EMF stimulation to examine differential gene expression in injured versus non-injured cortex tissue. The authors report multiple differentially expressed genes linked to immune infiltration, myelination, oxidative stress…

Comparison of pulsed and continuous electromagnetic field generated by WPT system on human dermal and neural cells.

Research RF Safe Research Library Jan 1, 2024

This in vitro study tested electromagnetic fields generated by a prototype wireless power transfer (wireless charging) system on four human dermal and neural cell lines. Across pulsed and continuous exposure conditions, the authors report no negative effects on morphology/cytoskeleton, viability/mitosis,…

Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway.

Research RF Safe Research Library Jan 1, 2023

This animal study examined whether lipoic acid modifies cognitive and hippocampal effects in young male rats exposed to EMF emitted from multiple cell phones. The authors report improved learning performance but impaired long-term memory consolidation after EMF exposure, alongside changes in hippocampal…

Effects of pulsed electromagnetic fields and N-acetylcysteine on transplantation of vitrified mouse ovarian tissue.

Research RF Safe Research Library Jan 1, 2023

This experimental mouse study tested whether N-acetylcysteine (NAC), pulsed electromagnetic fields (PEMF), or their combination improves outcomes after transplantation of vitrified ovarian tissue. The abstract reports increased follicle numbers and enhanced vascularization in NAC, PEMF, and NAC+PEMF groups, along…

Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Improves Neurological Outcome and Reduces Microglial Reactivity in a Rodent Model of Global Transient Stroke.

Research RF Safe Research Library Jan 1, 2023

This animal and laboratory study evaluated extremely low-frequency electromagnetic stimulation (ELF-EMS) in a rodent ischemia-reperfusion stroke model and related in vitro/slice experiments. The authors report improved neurological and behavioral outcomes, increased neuronal survival, and reduced glial/microglial…

Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.

Research RF Safe Research Library Jan 1, 2023

This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…

Optimization of cacao beans fermentation by native species and electromagnetic fields.

Research RF Safe Research Library Jan 1, 2023

This study optimized cacao bean fermentation for the CCN 51 clone using native microbial species and applied magnetic fields, varying field density, exposure time, and inoculum concentration. It reports improved yield and bean quality versus a no-magnetic-field control at an optimized condition (5 mT, 22.5 min, 1.6%…

Magnetofection of miR-21 promoted by electromagnetic field and iron oxide nanoparticles via the p38 MAPK pathway contributes to osteogenesis and angiogenesis for intervertebral fusion.

Research RF Safe Research Library Jan 1, 2023

This study describes a magnetofection system using electromagnetic field (EMF) co-stimulation with iron oxide nanoparticles (IONPs) to deliver miR-21. The authors report increased transfection efficiency and promotion of osteogenesis and angiogenesis in BMSCs and HUVECs, with downstream application to…

The effects of RF coils and SAR supervision strategies for clinically applicable nonselective parallel-transmit pulses at 7 T.

Research RF Safe Research Library Jan 1, 2023

This engineering study evaluated how different 7T parallel-transmit head coils and SAR supervision strategies affect nonselective pTx pulse design for a 3D-MPRAGE sequence. It reports that FOCUS pulses were more robust than universal pulses when applied across different coils, and that FOCUS inversion pulses…

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