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The Systematic Review on RF-EMF Exposure and Cancer by Karipidis et al. (2024) has Serious Flaws that Undermine the Validity of the Study's Conclusions

Research RF Safe Research Library Jan 1, 2024

This letter critiques the WHO-sponsored systematic review by Karipidis et al. (2024) on RF-EMF exposure and cancer risk. The authors argue the review has serious methodological and interpretative flaws, including issues with study selection and data analysis. They contend that the review’s conclusion of "no clear…

Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment

Research RF Safe Research Library Jan 1, 2024

Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also…

Sex-dependent impact of perinatal 5G electromagnetic field exposure in the adolescent rat behavior.

Research RF Safe Research Library Jan 1, 2023

This animal study examined daily perinatal 5G EMF exposure in rats at the ICNIRP whole-body public exposure limit (maternal SAR 0.07 W/kg) from gestational day 8 to post-natal day 21. The authors report a 1-day delay in incisor eruption in both sexes and sex-dependent changes in stereotyped behavior in the open field…

Electromagnetic field stimulation facilitates motor neuron excitability, myogenesis and muscle contractility in spinal cord transected rats.

Research RF Safe Research Library Jan 1, 2022

This animal study evaluated whole-body EMF stimulation in a rat model of complete spinal cord injury. Compared with SCI alone, EMF exposure for 7 or 14 days was reported to improve electrophysiological measures of motor neuron excitability and enhance soleus muscle contractile performance. Histopathology and protein…

Electromagnetic Field Stimulation Attenuates Phasic Nociception after Complete Spinal Cord Injury in Rats.

Research RF Safe Research Library Jan 1, 2021

This animal study evaluated whole-body extremely low-frequency EMF stimulation after thoracic complete spinal cord injury in adult male rats. The authors report reduced nociceptive behaviors (hyperalgesia/allodynia) from week 6 onward and restoration of spinal reflexes by week 8. They also report lower glutamate at…

Exposure to RF-EMF Alters Postsynaptic Structure and Hinders Neurite Outgrowth in Developing Hippocampal Neurons of Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2021

This animal and primary neuron culture study exposed early postnatal mice to whole-body RF-EMF (SAR 4.0 W/kg) for 5 hours/day from P1 to P28. The authors report reductions in dendritic spine measures (notably mushroom-type spines), decreased glutamate receptor expression in mushroom-type spines, and lower BDNF…

Occupational Exposure to Electromagnetic Fields and Health Surveillance According to the European Directive 2013/35/EU.

Research RF Safe Research Library Jan 1, 2021

This review discusses mandatory health surveillance for EMF-exposed workers under EU Directive 2013/35/EU, which focuses on preventing known direct biophysical and indirect effects. It notes that long-term effects are not covered because evidence for a causal relationship is considered inadequate. The authors report…

Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.

Research RF Safe Research Library Jan 1, 2020

This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…

Electromagnetic field affects the voltage-dependent potassium channel Kv1.3.

Research RF Safe Research Library Jan 1, 2020

This in vitro study tested whether extremely low-frequency electromagnetic fields (ELF-EMF) modulate the voltage-gated potassium channel Kv1.3 in Kv1.3-expressing CHO-K1 cells. Cells were exposed to a 20 Hz field at 268 µT or 902 µT while Kv1.3 currents were measured by whole-cell patch clamp. The authors report a…

Wideband Self-Grounded Bow-Tie Antenna for Thermal MR.

Research RF Safe Research Library Jan 1, 2020

This engineering study designed and tested a compact wideband self-grounded bow-tie RF antenna module for a whole-body 7.0 T MRI system, aiming to enable 1H/19F MRI, MR thermometry, and broadband RF thermal intervention. The authors report validated B1 efficiency measurements and phantom-based heating experiments…

The specific absorption rate in different brain regions of rats exposed to electromagnetic plane waves.

Research RF Safe Research Library Jan 1, 2019

This study develops a numerical voxel rat model with 10 segmented brain regions to evaluate region-specific dosimetry under plane-wave EMF exposure. It reports that brain-region averaged SAR varies with frequency, incidence direction, and E-polarization direction. The authors also report potentially large deviations…

Hepatocellular carcinoma therapy finds a channel on the radio

Research RF Safe Research Library Jan 1, 2019

This EBioMedicine commentary discusses tumour-specific amplitude-modulated RF EMF as an anti-cancer therapy for hepatocellular carcinoma and highlights Cav3.2 (CACNA1H) T-type calcium channels as a proposed mediator of the effect. It notes that the reported whole-body averaged SAR in a treated HCC patient was below…

Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones

Research RF Safe Research Library Jan 1, 2018

This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart,…

Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients.

Research RF Safe Research Library Jan 1, 2018

This study evaluated ELF-EMF magnetotherapy as an adjunct to post-acute ischemic stroke rehabilitation in 57 patients, comparing those who received ELF-EMF therapy with those who did not. The authors report that oxidative stress markers (TBARS, thiol, and carbonyl groups) decreased more in the ELF-EMF group than in…

Evaluation of MRI RF electromagnetic field induced heating near leads of cochlear implants.

Research RF Safe Research Library Jan 1, 2018

This simulation study evaluated RF-induced heating near cochlear implant leads during 1.5 T MRI using a transfer function method. Across studied configurations, the average temperature rise was 0.79 °C and the maximum was 2.80 °C at a whole-body average SAR of 2 W/kg. The authors report that lead trajectory and MRI…

2.45 GHz microwave radiation induced oxidative and nitrosative stress mediated testicular apoptosis: Involvement of a p53 dependent bax-caspase-3 mediated pathway.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed 12-week-old male mice to 2.45 GHz continuous-wave microwave radiation (average power density 0.0248 mW/cm; whole-body SAR 0.0146 W/kg) for 2 hours/day over 15, 30, or 60 days. The authors evaluated testicular histology, testosterone, oxidative/nitrosative stress markers, antioxidant enzymes,…

NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595

Research RF Safe Research Library Jan 1, 2018

This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…

No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.

Research RF Safe Research Library Jan 1, 2017

This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…

The Effects of Precautionary Messages about Electromagnetic Fields from Mobile Phones and Base Stations Revisited: The Role of Recipient Characteristics.

Research RF Safe Research Library Jan 1, 2017

This survey experiment tested how precautionary messages about RF-EMFs from mobile phones and base stations affect recipients' threat perceptions and emotional distress. The effect of precautionary information on threat perception depended on individual differences, particularly trait anxiety and gender. The study…

Microwave radiation (2.45 GHz)-induced oxidative stress: Whole-body exposure effect on histopathology of Wistar rats.

Research RF Safe Research Library Jan 1, 2017

This animal study examined whole-body exposure to 2.45 GHz microwave radiation for 2 h/day over 35 days in male Wistar rats. The authors report increased lipid peroxidation (LPO) in liver, brain, and spleen and histological changes across multiple organs compared with sham-exposed controls. They conclude the exposure…

Radiation from wireless technology elevates blood glucose and body temperature in 40-year-old type 1 diabetic male.

Research RF Safe Research Library Jan 1, 2017

This case report describes a 40-year-old male with type 1 diabetes who reported repeated episodes of markedly elevated blood glucose associated with nearby microwave radiation from wireless technology, with decreases after exposure ended. In one episode, body temperature also increased, and both measures reportedly…

Effects of electromagnetic field (1.8/0.9 GHz) exposure on growth plate in growing rats.

Research RF Safe Research Library Jan 1, 2016

This animal study examined whole-body RF-EMF exposure (900 or 1800 MHz) for 2 hours/day over 90 days in growing male rats, compared with sham controls. Exposed rats showed greater weight and length increases and higher levels of several hormones and calcium. The study also reports changes in femoral growth plate…

Cardiac magnetic resonance radiofrequency tissue tagging for diagnosis of constrictive pericarditis: A proof of concept study.

Research RF Safe Research Library Jan 1, 2016

This proof-of-concept cohort study evaluated cardiac magnetic resonance (CMR) radiofrequency tissue tagging to diagnose constrictive pericarditis and compared results with surgical findings and cardiac catheterization. In 16 patients who underwent pericardiectomy, CMR positivity agreed 100% with intraoperative…

Memory performance, wireless communication and exposure to radiofrequency electromagnetic fields: A prospective cohort study in adolescents

Research RF Safe Research Library Jan 1, 2015

This prospective cohort study followed 439 adolescents for one year to assess whether wireless device use and estimated RF-EMF dose were associated with changes in memory performance. Higher cumulative mobile phone call duration and higher modeled RF-EMF brain and whole-body dose were associated with decreases in…

Effects of Wi-Fi (2.45 GHz) Exposure on Apoptosis, Sperm Parameters and Testicular Histomorphometry in Rats: A Time Course Study

Research RF Safe Research Library Jan 1, 2015

This animal experimental study exposed male Wistar rats to 2.45 GHz Wi-Fi radiation for 1 or 7 hours per day over two months and compared them with unexposed controls. The abstract reports time-dependent decreases in sperm parameters alongside increased apoptotic markers (apoptosis-positive cells and caspase-3…

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