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This animal study examined whether serotonergic signaling modifies analgesia associated with repeated ELF electromagnetic field exposure. Sixty-six male Wistar rats were exposed to 50 Hz, 5 mT for 2 hours/day over 15 days and then received 5-HT agonists or antagonists before analgesia testing. Agonists increased,…

This in vitro study examined how morphine, a 50-Hz 0.50 mT electromagnetic field (intermittent), and cisplatin co-treatments affected DNA repair gene expression and cytotoxicity in MCF-7 and SH-SY5Y cells. Morphine alone was reported to down-regulate examined DNA repair genes, whereas morphine plus EMF did not…

This laboratory study tested whether brief ELF-EMF seed pretreatment could enhance cadmium accumulation in white mustard seedlings. Seeds exposed to 50 Hz alternating EMF (60 or 120 mT) for 1 minute produced shoots with higher cadmium content than controls, while biomass was unchanged. The authors suggest potential…

This in vitro study exposed MCF-7 and SH-SY5Y cells to a 50 Hz, 0.50 mT electromagnetic field in combination with cisplatin and/or morphine. The combined "CDDP+Mor+EMF" condition showed higher cisplatin IC values than cisplatin alone and "CDDP+Mor" in both cell lines, consistent with reduced cisplatin cytotoxicity.…

This animal study evaluated whether extremely low frequency EMF exposure affects bone loss in a levothyroxine-induced hyperthyroidism rat model. Rats exposed to 15 Hz/1 mT EMF plus levothyroxine showed improved bone mineral density, mechanical measures, and partially restored trabecular bone architecture compared…

This in vitro study tested 50 Hz, 3 mT electromagnetic field (EMF) exposure and 808 nm low-level laser (LLL), alone and combined, on human adipose tissue-derived mesenchymal stem cells from six donors. The authors report increased cell numbers after 7 days with EMF, greater increases with LLL, and the largest…

This in vitro study exposed human keratinocyte cells (NCTC 2544) to 50 Hz ELF-EMF at 0.25–2 G and assessed oxidative stress-related endpoints. Significant increases in ROS were reported at 0.5 and 1 G, with associated short-term changes in antioxidant and lipid peroxidation markers. The authors report that…

This paper describes an on-line ELF magnetic stimulation setup and evaluates coil field distribution using COMSOL simulations alongside physical measurements. The authors report that modeled and measured magnetic flux densities were similar, and that stimulation induced sodium channel currents and fEPSPs in rat…

This animal study examined whether extremely low frequency electromagnetic field exposure alters morphine analgesia and tolerance in rats. Rats exposed to a 50 Hz magnetic field (reported as 5 mT) showed higher morphine analgesic effects than rats given morphine without field exposure. In morphine-tolerant rats,…

This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…

This in vitro study examined whether a 50-Hz, 0.50 mT intermittent electromagnetic field modifies responses to cisplatin and bleomycin in MCF-7 and SH-SY5Y cells. The authors report increased susceptibility in MCF-7 cells with EMF added to cisplatin+bleomycin, while SH-SY5Y susceptibility was unchanged. They also…

This in vitro study exposed rat adipose-derived stem cells to a pulsed electromagnetic field (7 Hz, 30 mT) and assessed viability by flow cytometry. The authors report that a low-fat diet was protective in PEMF-exposed ADSCs, especially in pups. They also report a higher proportion of early apoptotic cells in…

This animal study tested four frequency-band EMF exposures (1–50,000 Hz variants) in an ovariectomized mouse model of osteoporosis over 8 weeks (3 h/day). Low- and band-pass exposures increased bone formation markers and osteogenesis-related gene expression, while high-pass exposure decreased both formation and…

This animal study evaluated whether 50 Hz EMF exposure enhances wound healing after transplantation of human epidermal stem cells (ESC) seeded in collagen sponge scaffolds. Thirty-six nude mice with full-thickness wounds were assigned to control, ESC-only, or ESC+EMF groups (50 Hz, 5 mT, 60 min/day for 20 days). The…

This animal and in vitro study reports a method to lyse tumor cells mechanically using targeted superparamagnetic iron oxide nanoparticles rotated by a weak alternating magnetic field. Nude mice with head and neck tumors received cetuximab-coated nanoparticles and 4 Hz field exposures for 30 minutes on alternating…