Increase in Blood Levels of Growth Factors Involved in the Neuroplasticity Process by Using an Extremely Low Frequency Electromagnetic Field in Post-stroke Patients.
This study evaluated whether adding extremely low-frequency electromagnetic field (ELF-EMF) therapy to standard post-stroke rehabilitation affects biomarkers of neuroplasticity and functional recovery. Forty-eight patients completed the same rehabilitation program, with the study group additionally receiving 10 ELF-EMF treatments. The authors report increased neuroplasticity-related growth factors/cytokines and improved functional outcomes after 4 weeks, with BDNF changes correlating with several clinical scales.
Key points
- The study involved 48 post-stroke patients split into two rehabilitation groups, with one group receiving additional ELF-EMF treatments.
- Neuroplasticity-related biomarkers measured included plasma BDNF, VEGF, and multiple cytokines/growth factors, plus BDNF mRNA expression.
- After 4 weeks, the ELF-EMF group was reported to have higher levels of growth factors and cytokines involved in neuroplasticity.
- Functional recovery was assessed using Barthel Index, MMSE, GDS, NIHSS, and mRS.
- The authors report that ELF-EMF promoted enhanced functional recovery compared with rehabilitation alone.
- Changes in plasma BDNF were reported to correlate positively with Barthel Index and MMSE and negatively with GDS.
- The abstract suggests the observed effects may be related to increased gene expression at the mRNA level.
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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