Archive

This narrative review discusses bioelectricity arising from membrane potentials and its role in morphogenesis beyond neural tissues. It reports that evidence supports bioelectric signals influencing embryonic development, tissue repair, and disease-related processes, and summarizes cellular mechanisms for generating…

This exposure-assessment study analyzed two years of continuous frequency-selective monitoring from 13 sensors in the five largest cities in Greece, focusing on the 3.6 GHz 5G band. It reports a gradual increase in 3.6 GHz environmental EMF levels over time and greater variability than legacy cellular bands, with…

This review synthesizes evidence that electromagnetic field (EMF) exposure is associated in the literature with changes in systemic and cellular iron metabolism, with reported effects varying by EMF parameters, exposure duration, and biological context. It proposes mechanistic pathways involving iron-containing…

This animal proof-of-concept study describes an engineered nanoparticle–cell interface (EMPOWER) enabling wireless regulation of transgene expression using a 1-kHz magnetic field. Chitosan-coated multiferroic nanoparticles reportedly generate intracellular ROS that activates KEAP1/NRF2 biosensors connected to…

This paper presents a thermodynamic model intended to explain how extremely low-frequency electromagnetic fields (ELF-EMFs) may interact with cells. The authors propose that ELF-EMFs directly interfere with the cellular membrane, producing biological responses linked to energy conversion and changes in flows across…

This in vitro study exposed B16-BL6 melanoma cells to a time-varying EMF modeled after intercellular calcium-wave firing patterns. The abstract reports a 50.3% reduction in viable cells after a single 40-minute exposure and microscopy findings consistent with apoptosis and nuclear fragmentation versus control. The…

This mouse study tested whether alternating current electromagnetic field (EMF) exposure modifies muscle lipid accumulation during long-term high-fat feeding. Mice exposed to EMF (8 hours/day for 16 weeks; maximum 180 mT) while on a high-fat diet had lower intramyocellular lipid levels than high-fat diet controls.…

This in vitro study describes a microfluidic device integrated with a radiofrequency exposure system to enable on-chip monitoring of cellular responses under a 1.8 GHz field. Using human amniotic epithelial cells, the authors report field-intensity-associated increases in protrusions/filopodia, changes in…

This preprint describes an in vitro bioreactor-based system to test whether electromagnetic/electrical stimulation affects extracellular vesicles (EVs). Using proteomics and single-vesicle flow cytometry, the authors report that stimulation at physiological current amplitudes can modulate EV content in a…

This paper reviews literature from 1980–2023 on the role of electromagnetic fields as a therapy for traumatic brain injury and brain neuropathology. It reports that existing findings suggest electromagnetic therapy may be a promising non-invasive treatment approach. The authors emphasize that current evidence is…

This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…

This review discusses low-energy amplitude-modulated RF EMF (27.12 MHz carrier with low Hz–kHz envelope modulation) delivered systemically via intrabuccal antenna devices as a potential treatment for advanced hepatocellular carcinoma. It reports preclinical inhibition of cancer growth in vitro and in mouse xenograft…