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441 postsMagneto-oncology: a radical pair primer
This mini-review discusses the radical pair mechanism as a plausible biophysical route by which external magnetic fields could influence biochemical processes in living systems. It is intended as a primer for magneto-oncology researchers to assess whether observed magnetic-field-related biomedical effects may be explained by radical pair biochemistry. The article also notes the value of this framework for refining therapeutic protocols and for identifying potential experimental artifacts in oncology-related magnetic field research.
Sensation of electric fields in the Drosophila melanogaster larva
This animal study reports that Drosophila melanogaster larvae can sense electric fields and exhibit robust electrotaxis toward the cathode in controlled environments. The authors identify head-tip sensory neurons required for this behavior and report calcium-imaging evidence that Gr66a-positive neurons encode field strength and orientation. The work supports electrosensation as a functional sensory modality in Drosophila larvae and demonstrates measurable neural and behavioral responses to electric fields under the studied conditions.
Is Cellphone Carrying Below the Waist (Exposure to Non-Ionizing Radiation) Contributing to the Rapid Rise in Early-Onset Colorectal Cancer?
This conference abstract reports a pilot matched case-control study examining whether carrying a cellphone below the waist is associated with early-onset colorectal cancer (EOCRC). The authors report higher EOCRC likelihood among those who carried phones below the waist, with the strongest association for ipsilateral carrying (same side as the tumor) and high cumulative hours. Details on exposure measurement, confounding control, and full statistical reporting are not provided in the abstract.
Electric and Magnetic Field Technologies in Agriculture: Plant Responses, Experimental Limitations, and Future Directions
This narrative review discusses how electric and magnetic field technologies are applied in agriculture and how plants may respond. It proposes a model to explain potential mechanistic convergence between electric and magnetic field effects. The review highlights several suggested mechanisms, including membrane permeability changes, reactive oxygen species/antioxidant responses, altered ion transport, and DNA/gene expression changes.
Prospective cohort study on non-specific symptoms, cognitive, behavioral, sleep and mental health in relation to electronic media use and transportation noise among adolescents (HERMES): study protocol
This protocol describes the third wave of the HERMES prospective adolescent cohort in Switzerland, with follow-up every four months and at one year. The study will assess electronic media use, modeled RF-EMF and transportation noise exposures, and a range of outcomes including cognition, behavior, sleep, mental health, and non-specific symptoms. A subsample will undergo personal RF-EMF measurements and accelerometer-based sleep/physical activity tracking.
The Impact of Mobile Phone Electromagnetic Waves on the Neurons and Blood Brain Barrier Integrity in the Chick Embryo
This animal study exposed chick embryos to electromagnetic waves from a mobile phone and compared them with unexposed controls. Electron microscopy on days 10 and 15 reported neuronal and cerebellar cellular alterations in the exposed group, including features described as apoptosis and mitochondrial swelling. The authors also report compromised blood-brain barrier integrity and conclude the exposure adversely affects brain development.
Role of radio-frequency electromagnetic waves in causing oxidative stress
This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in cardiomyocytes and hepatocytes. The authors conclude that radio-frequency electromagnetic waves can induce oxidative stress and mitochondrial damage in developing embryos.
The use of different exposure metrics in the research about the health impacts of electromagnetic fields
This policy brief focuses on how RF-EMF exposure should be quantified in health research, emphasizing the role of near-field sources and proposing cumulative dose (J/kg/day) as a health-relevant metric. It reports mean cumulative dose estimates of 0.29 J/kg/day for the whole body and 0.81 J/kg/day for the brain. The brief notes established RF-EMF effects (heating, microwave hearing under highly pulsed radiation, and stimulation) and discusses indications of biological effects below thermal thresholds, while stating that improved metrics do not by themselves confirm harm.
Temporal Change of Outdoor Rf-Emf Levels Four in European Countries: A Microenvironmental Measurement Study
This microenvironmental measurement study assessed temporal trends in outdoor RF-EMF exposure from 2016 to 2023 in four European countries using repeated walking-route measurements with exposimeters. The abstract reports that data did not suggest significant changes in mobile base station (downlink) exposure over time and that trends were not consistent across individual microenvironments. Reported median downlink exposure values varied by country and year but did not indicate an overall increase despite higher mobile data traffic.
Experimental Study of Animal Behavior under the Influence of the Electromagnetic Field of the 5G Mobile Communication Standard
This pilot animal study exposed mature male Wistar rats to 4.9 GHz electromagnetic fields described as 5G-standard, for 15 days (2 hours/day) in a semi-anechoic shielded chamber. Open-field testing found no clear behavioral differences between unmodulated and modulated exposures. Statistically significant behavioral changes occurred in both exposed and control animals, which the authors attribute to changes in the environmental electromagnetic background, making causal interpretation uncertain.
Effect of Repeated Exposure to Complexly Organized Electromagnetic Radiation on the Rat Behavior in the "Open Field" Test
This animal study examined repeated pulsed-modulated RF exposure (1–4 GHz; total pulse power density 300 μW/cm2) in male and female Wistar rats and assessed behavior using the open field test. The abstract reports stress reactions and long-term memory impairment in some rats, with females described as more sensitive than males. Reported effects were transient, with behavior returning to baseline within 1.5–2 months after exposure stopped. The authors suggest potential concern for constant exposure scenarios, though this is not directly evaluated in humans here.
Experimental Study of Stress Reactions Induced by Low-Intensity Microwave Radiation
This animal experiment examined hematopoietic and immune-related indicators in mice after repeated exposure to low-intensity microwave radiation. Exposure involved monochromatic pulsed fields in the 2.27–2.78 GHz range with average power flux density of 60 μW/cm² and doses of 0.086–0.86 J/g. The authors report cumulative biological effects consistent with a stress-like adaptive reaction, based on changes in bone marrow, spleen CFU-S measures, erythrocyte hemolytic resistance, and thymus metrics.
A Decision Support System for Managing Health Symptoms of Living Near Mobile Phone Base Stations
This analytical study evaluated machine learning models (SVM and Random Forest) to predict health symptoms in adults living near mobile phone base stations. The SVM model reportedly achieved high predictive performance for headache, sleep disturbance, dizziness, vertigo, and fatigue, and outperformed Random Forest and prior models. The abstract concludes that proximity to base stations is connected with increased prevalence of several symptoms and emphasizes distance, age, and duration of residence as key predictors.
Mitigating Heat-Induced Sperm Damage and Testicular Tissue Abnormalities: The Protective Role of Radiofrequency Radiation from Wi-Fi Routers in Rodent Models
This rodent study examined whether 2.45 GHz Wi‑Fi router RF-EMF exposure could mitigate heat-stress-related reproductive damage in male rats. The combined RF-EMF + heat group reportedly had improved testicular structure measures and sperm quality versus heat-only, while RF-EMF alone was also reported to alter testis and sperm parameters. The authors interpret the findings as potentially consistent with an adaptive response and call for more research on mechanisms and safety.
The Systematic Review on RF-EMF Exposure and Cancer by Karipidis et al. (2024) has Serious Flaws that Undermine the Validity of the Study's Conclusions
This letter critiques the WHO-sponsored systematic review by Karipidis et al. (2024) on RF-EMF exposure and cancer risk. The authors argue the review has serious methodological and interpretative flaws, including issues with study selection and data analysis. They contend that the review’s conclusion of "no clear evidence" may be misleading and should not be used as a basis for health policy or safety guidelines.
Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data
This animal study examined whether continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) affects thyroid tissue in rat offspring at 6 months. The exposed group showed significantly increased mononuclear cell infiltration and vascular congestion in thyroid histology. TUNEL-positive cell percentage and H2A.X antibody levels did not differ significantly between groups.
Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment
Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also highlights disagreement with the 2024 WHO review and raises methodological concerns about WHO conclusions.
The effects of radiofrequency exposure on male fertility: A systematic review of human observational studies with dose-response meta-analysis (SR 3)
This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the findings as consistent with potential reproductive health risks and call for continued risk assessment and guideline development.
Effects of radiofrequency field from 5G communication on fecal microbiome and metabolome profiles in mice
This animal study exposed adult male C57BL/6 mice to a 4.9 GHz radiofrequency field for three weeks (1 hour/day) and compared them with a sham group. The abstract reports altered fecal microbiome composition with reduced diversity in the RF group, along with 258 significantly differentially abundant fecal metabolites. The authors conclude that 4.9 GHz RF exposure is associated with changes in gut microbiota and metabolic profiles and call for further EMF safety research.
Toxicology and carcinogenesis studies in Sprague Dawley (Hsd:Sprague Dawley SD) rats exposed to whole-body radio frequency radiation at a frequency (900 MHz) and modulations (GSM and CDMA) used by cell phones
This National Toxicology Program technical report describes 900 MHz whole-body RFR exposures (GSM and CDMA) in male and female Sprague Dawley rats from in utero through up to 2 years. The report concludes clear evidence of carcinogenic activity in males for both modulations based on malignant schwannoma of the heart, with malignant glioma of the brain also reported as related to exposure. In females, the report concludes equivocal evidence of carcinogenic activity for both modulations based on selected tumor outcomes, and genetic toxicology findings were mixed with some comet assay increases/equivocal results but negative micronucleus assays.
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following a subsequent 3 Gy Co-60 gamma challenge.
Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor
This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are probably similar, with plant two-pore channels proposed as plausible mediators due to a comparable voltage sensor. The abstract describes briefly reviewed plant studies as consistent with this mechanism, but does not provide detailed exposure parameters or quantitative results.
Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression
This 2016 narrative review proposes that non-thermal microwave/lower-frequency EMFs act primarily through activation of voltage-gated calcium channels (VGCCs), with calcium channel blockers reported to block EMF effects. It summarizes animal, occupational, and epidemiological literature and reports that exposures from base stations, heavy mobile phone use, and wireless smart meters are associated with neuropsychiatric symptoms, sometimes with doseresponse patterns. The author concludes that multiple lines of evidence collectively support that non-thermal microwave EMF exposures can produce diverse neuropsychiatric effects including depression.
Effects of GSM modulated radio-frequency electromagnetic radiation on permeability of blood-brain barrier in male & female rats
This rat study examined whether pulse-modulated 900 MHz and 1800 MHz RF exposure affects blood-brain barrier permeability using Evans blue dye. The abstract reports increased permeability in male rats at both frequencies (stronger at 1800 MHz) and in female rats at 900 MHz but not at 1800 MHz. The authors suggest mobile-phone-like RF exposure could increase blood-brain barrier permeability under non-thermal conditions, while noting that further mechanistic studies are needed.
Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats
This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1 expression and ERK dephosphorylation, proposing activation of the mkp-1/ERK pathway as a mechanism.