Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats
This rat study examined repeated 3.5 GHz RF exposure (2 hours/day, 5 days/week for 30 days) and thyroid-related outcomes, with and without quercetin. The abstract reports altered thyroid hormones (lower T3/T4, higher TSH) and increased oxidative stress in thyroid tissue after RF exposure. Quercetin appeared partially protective, though effects were not uniformly statistically significant, and SAR simulations indicated relatively higher absorption in the thyroid region.
Key points
- Twenty-eight male Wistar rats were randomized into Sham, RF, Quercetin, and RF + Quercetin groups.
- RF exposure at 3.5 GHz was administered for 2 hours/day, 5 days/week, over 30 days.
- RF exposure was reported to decrease serum T3 and T4 and increase TSH compared with sham.
- Thyroid tissue oxidative stress markers shifted toward oxidative stress (higher MDA and TOS; lower TAS and GSH) after RF exposure.
- Quercetin (20 mg/kg, intraperitoneal) showed partial trends toward reversing RF-associated changes, but not all were statistically significant.
- SAR simulations reported higher energy absorption in the thyroid region with an average SAR of 1.128 W/kg.
Referenced studies & papers
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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