P53 status, and G2/M cell cycle arrest, are determining factors in cell-death induction mediated by ELF-EMF in glioblastoma.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested ELF-EMF exposure in U87 and U251 glioblastoma cell lines and assessed apoptosis, cell-cycle distribution, cell size, and mRNA expression of cell-cycle genes. The authors report higher apoptosis induction and increased G2/M arrest in U87 compared with U251, alongside increased U87 cell size…
Extremely low-frequency electromagnetic field exposure alters DNA methylation levels in the endometrium of pigs during the peri-implantation period.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study exposed porcine endometrial slices from the peri-implantation period (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed promoter DNA methylation in selected genes. The authors report increased methylation for EGR2, ID2, and PTGER4, decreased methylation for IL1RAP and NOS3, and no…
Transcriptome profiling of flax plants exposed to a low-frequency alternating electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2023
This study aims to perform transcriptome profiling in flax plants exposed to a low-frequency alternating electromagnetic field. The abstract frames prior work as suggesting EMF-related changes in free radical homeostasis and altered expression of genes involved in stress responses, ion transport, and cell wall…
Ameliorative effects of crocin against electromagnetic field-induced oxidative stress and liver and kidney injuries in mice.
Research
RF Safe Research Library
Jan 1, 2023
This mouse experiment evaluated whether crocin (50 mg/kg) mitigates liver and kidney injury associated with 2100 MHz electromagnetic field exposure. EMF exposure was associated with increased serum markers of kidney and liver injury, reduced antioxidant enzyme activity, and histopathological/ultrastructural changes…
Synergistic cytotoxic effects of an extremely low-frequency electromagnetic field with doxorubicin on MCF-7 cell line.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study tested whether a 50 Hz, 20 mT extremely low-frequency electromagnetic field (ELF-EMF) enhances the cytotoxic effects of doxorubicin (DOX) in the MCF-7 breast cancer cell line. The authors report that combining ELF-EMF with low-dose DOX reduced cell viability at lower DOX concentrations than DOX…
Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways.
Research
RF Safe Research Library
Jan 1, 2023
This animal study examined EMF exposure in a mouse high-fat diet model of NAFLD. The authors report that EMF exposure reduced hepatic lipid accumulation and markers of oxidative stress, alongside changes consistent with activation of CaMKKβ/AMPK and Nrf2-related signaling. The abstract concludes EMF could be a…
Electromagnetic Fields Literature Analysis for Precision Medicine.
Research
RF Safe Research Library
Jan 1, 2023
This paper describes a literature-mining analysis of more than 30,000 EMF-related publications to extract genes, diseases, and molecular mechanisms linked to EMF exposure across six EMF subsets. The authors report identifying 3,653 unique disease MeSH terms and 9,966 unique genes, including 4,340 human genes. The…
Advanced Radio Frequency Applicators for Thermal Magnetic Resonance Theranostics of Brain Tumors.
Research
RF Safe Research Library
Jan 1, 2023
This engineering/simulation study evaluates RF applicator array designs for Thermal Magnetic Resonance (ThermalMR), which combines MRI with RF hyperthermia for brain tumor theranostics. Using EMF and temperature simulations at 7.0 T, 9.4 T, and 10.5 T, hybrid loop+SGBT dipole arrays are reported to provide superior…
Low-energy amplitude-modulated electromagnetic field exposure: Feasibility study in patients with hepatocellular carcinoma.
Research
RF Safe Research Library
Jan 1, 2023
This single-site feasibility trial evaluated repeated 90-minute amplitude-modulated EMF exposure (AutEMdev) in 66 patients with advanced hepatocellular carcinoma. The primary focus was safety and hemodynamic variability during exposure, with exploratory outcomes including quality of life, survival, and tumor…
Exposure to a 900 MHz electromagnetic field induces a response of the honey bee organism on the level of enzyme activity and the expression of stress-related genes.
Research
RF Safe Research Library
Jan 1, 2023
This animal study exposed one-day-old worker honey bees to 900 MHz RF-EMF at 12, 28, or 61 V/m for 15 minutes, 1 hour, or 3 hours, with an unexposed control group. The authors report changes in hemolymph enzyme activity and in expression of several stress-related genes following exposure. They state the pattern…
Electromagnetic fields - do they pose a cardiovascular risk?
Research
RF Safe Research Library
Jan 1, 2023
This study assessed short-term autonomic cardiac responses to RF EMF exposure using HRV metrics in 30 healthy young adults. During 2400 MHz (Wi-Fi) exposure applied to the chest for 5 minutes, HF-HRV decreased and the sympathetic-related 0V% index increased compared with 2600 MHz (4G) exposure, while RR intervals did…
Measuring and assessing the effects of extremely low-frequency electromagnetic fields (ELF-EMF) on blood parameters and liver enzymes of personnel working in high voltage power stations in a petrochemical industry.
Research
RF Safe Research Library
Jan 1, 2023
This cross-sectional study in a petrochemical industry compared 50 high-voltage power-station workers exposed to ELF-EMF with 50 controls. Electric and magnetic fields were measured at 200 points, and blood parameters and liver enzymes were extracted from medical records. The study reports no significant differences…
Impact of ketamine administration on chronic unpredictable stress-induced rat model of depression during extremely low-frequency electromagnetic field exposure: Behavioral, histological and molecular study.
Research
RF Safe Research Library
Jan 1, 2023
This animal study evaluated ketamine administration combined with extremely low-frequency electromagnetic field (ELF-EMF) exposure in a chronic unpredictable stress (CUS) rat model. The authors report that the combined treatment increased depression-like behavior and neuronal degeneration, reduced GFAP(+) cells in…
Intermittent Exposure to a 16 Hz Extremely Low Frequency Pulsed Electromagnetic Field Promotes Osteogenesis In Vitro through Activating Piezo 1-Induced Ca Influx in Osteoprogenitor Cells.
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…
The effect of the electromagnetic field on the physicochemical properties of isolated corn starch obtained of plants from irradiate seeds.
Research
RF Safe Research Library
Jan 1, 2023
This study examined whether exposing maize seeds to electromagnetic fields (23, 70, 118 μT) for 15 days alters physicochemical properties of starch isolated from the resulting grains. SEM and X-ray diffraction results suggest starch morphology and orthorhombic crystalline structure were largely unchanged, though…
Immunomodulatory Effect of Electromagnetic Field in the Treatment of Traumatic Brain Injury.
Research
RF Safe Research Library
Jan 1, 2023
This paper reports a PubMed and Google Scholar-based review of EMF research related to brain pathology, with emphasis on ischemic and traumatic brain injury. It provides a critical overview of the state of the art and describes the authors’ experimental and ongoing studies. The authors conclude that EMF applications…
Effect of extremely low frequency electromagnetic field on the pathogenicity of Magnaporthe oryzae.
Research
RF Safe Research Library
Jan 1, 2023
This laboratory study examined Magnaporthe oryzae pathogenicity under extremely low frequency electromagnetic field exposure (50 Hz, 3 mT). The authors report increased infection ability, growth rate, and conidia generation with ELF-EMF exposure. They also report increased tolerance to a cell wall-perturbing agent…
Magnetofection of miR-21 promoted by electromagnetic field and iron oxide nanoparticles via the p38 MAPK pathway contributes to osteogenesis and angiogenesis for intervertebral fusion.
Research
RF Safe Research Library
Jan 1, 2023
This study describes a magnetofection system using electromagnetic field (EMF) co-stimulation with iron oxide nanoparticles (IONPs) to deliver miR-21. The authors report increased transfection efficiency and promotion of osteogenesis and angiogenesis in BMSCs and HUVECs, with downstream application to…
The effects of RF coils and SAR supervision strategies for clinically applicable nonselective parallel-transmit pulses at 7 T.
Research
RF Safe Research Library
Jan 1, 2023
This engineering study evaluated how different 7T parallel-transmit head coils and SAR supervision strategies affect nonselective pTx pulse design for a 3D-MPRAGE sequence. It reports that FOCUS pulses were more robust than universal pulses when applied across different coils, and that FOCUS inversion pulses…
Comparative Study of Extremely Low-Frequency Electromagnetic Field, Radiation, and Temozolomide Administration in Spheroid and Monolayer Forms of the Glioblastoma Cell Line (T98).
Research
RF Safe Research Library
Jan 1, 2023
This in vitro study assessed 50 Hz, 100 G extremely low-frequency EMF in combination with temozolomide and radiation in T98 glioblastoma cells grown as monolayers and spheroids. Radiation plus EMF increased apoptosis-related gene expression, while temozolomide plus EMF increased autophagy marker expression compared…
Low-energy amplitude-modulated radiofrequency electromagnetic fields as a systemic treatment for cancer: Review and proposed mechanisms of action
Research
RF Safe Research Library
Sep 8, 2022
This review discusses low-energy amplitude-modulated RF EMF (27.12 MHz carrier with low Hz–kHz envelope modulation) delivered systemically via intrabuccal antenna devices as a potential treatment for advanced hepatocellular carcinoma. It reports preclinical inhibition of cancer growth in vitro and in mouse xenograft…
The effect of long-term radiofrequency exposure on cognition in human observational studies: A protocol for a systematic review.
Research
RF Safe Research Library
Jan 1, 2022
This paper presents a protocol for a systematic review of human observational studies assessing long-term radiofrequency (100 kHz to 300 GHz) EMF exposure and cognitive outcomes. It plans to include cohort and case-control studies with at least 6 months follow-up and validated cognitive measures, and to evaluate…
Effects of repeated exposure to 50 Hz electromagnetic field on breast cancer cells.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study exposed two human breast cancer cell lines to a 50 Hz ELF-EMF (20 mT) for 3 hours/day for up to four days. The authors report reduced viability and apoptosis-related findings in MDA-MB-231 cells, with no significant viability change in MCF-7 cells. Cell-cycle effects differed by cell line,…
Hazardous effects of high voltage electromagnetic field on albino rats and protective role of Rosmarinus officinalis.
Research
RF Safe Research Library
Jan 1, 2022
This animal study examined effects of a 50 Hz high-voltage electromagnetic field (5.4 kV/m) applied 2 or 4 hours per day for 25 days in albino rats. The authors report decreases in RBC, haemoglobin, and catalase activity, with increases in WBCs, liver enzymes, bilirubin, kidney-related markers, and malondialdehyde…
Comment on: What is the radiation before 5G? A correlation study between measurements in situ and in real time and epidemiological indicators in Vallecas, Madrid, by I. López, N. Félix, M. Rivera, A. Alonso, and C. Maestú.
Research
RF Safe Research Library
Jan 1, 2022
This article is a comment on a previously published correlation study assessing whether RF-EMF exposure relates to survey-based health indicators such as sleep, headache, and fatigue. The authors state they performed a detailed analysis of the original study and offer clarifications. The abstract does not provide the…