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318 posts

Use of Electrical Household Appliances and Risk of All Types of Tumours: A Case-Control Study

Research RF Safe Research Library Jan 1, 2025

This multi-hospital case-control study (n=316) examined associations between use of common household electrical appliances emitting ELF EMF and tumour risk. Most devices showed below-unity odds ratios, while computer screen and microwave oven use showed slightly increased odds with wide confidence intervals. Proximity to electricity transformer stations was associated with higher tumour odds, whereas proximity to powerlines was not.

Magnetoreception and the ruling hypothesis

Research RF Safe Research Library Jan 1, 2025

This article is a commentary on how emotions and community dynamics can bias scientific reasoning when a favored hypothesis becomes a "ruling hypothesis." Using animal magnetoreception as an example, it argues that radical-pair/cryptochrome-centered frameworks may sometimes be treated as dominant, potentially leading to selective interpretation of evidence. The authors call for separating individual intent from community-wide bias and offer recommendations to mitigate these risks.

Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed pig conceptuses (days 15–16 of pregnancy) to 50 Hz ELF-EMF for 2 hours and assessed transcriptomic and DNA methylation changes. The authors report altered expression of 21 protein-coding transcripts and an approximately 16-fold increase in genomic DNA methylation, with promoter methylation changes in several named genes. They conclude ELF-EMF interacts with gene expression and DNA methylation processes during early development and call for further safety research.

Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes

Research RF Safe Research Library Jan 1, 2025

This six-year time series analysis used over 500,000 blood pressure measurements from two mid-magnetic latitude cities in China to examine associations with geomagnetic activity (Ap index). The study reports that blood pressure fluctuations correlate with geomagnetic activity and share similar periodic patterns, unlike air temperature and PM2.5. The authors conclude that high geomagnetic activity periods may increase risk for individuals with hypertension and note potential clinical and policy relevance.

Earth's magnetic field and its relationship to the origin of life, evolution and planetary habitability

Research RF Safe Research Library Jan 1, 2025

This review synthesizes evidence on Earth's geomagnetic field history and discusses how early establishment of the field (at least 4.2 billion years ago, inferred from zircon magnetism) may have supported planetary habitability via radiation shielding and water preservation. It highlights a proposed near-collapse of the dynamo near the end of the Precambrian and subsequent renewal in the earliest Cambrian, with potential implications for atmospheric escape and oxygenation. The paper frames several links to biological evolution (including Ediacara fauna) as possible and in some cases debated.

The effects of radiofrequency radiation on male reproductive health and potential mechanisms (Review)

Research RF Safe Research Library Jan 1, 2025

This narrative review summarizes human and animal research on radiofrequency (RF) radiation exposure (e.g., mobile phones, Wi‑Fi, occupational sources) and male reproductive outcomes. It reports that the literature links RF exposure with reduced sperm quality and increased DNA damage, often alongside oxidative stress and other proposed biological changes. Although inconsistencies are acknowledged, the authors conclude the overall evidence suggests harmful associations and call for standardized, long-term studies and reconsideration of guidelines.

Use of Mobile and Cordless Phones and the Association with Prostate Cancer

Research RF Safe Research Library Jan 1, 2025

This pooled analysis of two prior human studies reports increased odds of prostate cancer associated with mobile phone use, with higher estimates for longer latency and higher cumulative hours. Cordless phone use is reported to show increased risk but not statistically significant overall, with one mid-range cumulative use category showing an elevated OR. The abstract also reports higher risks among men with more aggressive prostate cancer and among those with a family history of prostate cancer.

RF-EMF exposure assessment with add-on uplink exposure sensor in different microenvironments in seven European countries

Research RF Safe Research Library Jan 1, 2025

This exposure assessment study introduces a cost-efficient add-on sensor attached to a smartphone to quantify auto-induced uplink RF-EMF transmission across 100–6000 MHz in multiple microenvironments. Activity-based surveys were conducted in seven European countries under non-user, maximum downlink, and maximum uplink scenarios. Reported power levels were lowest for non-user scenarios and higher during active use, with variation by country, urbanization, and setting. The authors frame the work as supporting future epidemiological research and planned validation against other tools.

Repeated Head Exposures to a 5G-3.5 GHz Signal Do Not Alter Behavior but Modify Intracortical Gene Expression in Adult Male Mice

Research RF Safe Research Library Jan 1, 2025

This animal study examined repeated asymmetrical head exposure to a 5G-modulated 3.5 GHz signal in adult male mice for six weeks. It reports no significant changes in locomotion, anxiety, or object-based memory performance under the tested conditions. However, it found statistically significant but limited cortical gene expression changes (<1% of expressed genes), including enrichment for glutamatergic synapse-related genes and lateralized differences involving mitochondrial genome-encoded genes. The authors caution that potential health risks from these intracortical transcriptomic modifications should not be downplayed and note uncertainties about longer exposures and other populations.

5G Radiofrequency Exposure Reduces PRDM16 and C/EBP � mRNA Expression, Two Key Biomarkers for Brown Adipogenesis

Research RF Safe Research Library Jan 1, 2025

This animal study exposed juvenile and young adult Wistar rats to 5G (3.5 GHz) or 2G (900 MHz) radiofrequency fields (1.5 V/m) for 1–2 weeks and measured brown adipose tissue-related gene expression by RT-qPCR. The abstract reports significant downregulation of PRDM16 and C/EBP mRNA after 5G exposure, while UCP1-dependent thermogenesis markers were not significantly changed at the transcriptional level. The authors interpret these findings as a potential partial disruption of brown adipocyte differentiation and raise EMF safety concerns, while calling for further confirmatory research.

The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation

Research RF Safe Research Library Jan 1, 2025

This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or increased anxiety-like behavior, respectively, suggesting a mechanistic link in this model.

Magneto-oncology: a radical pair primer

Research RF Safe Research Library Jan 1, 2025

This mini-review discusses the radical pair mechanism as a plausible biophysical route by which external magnetic fields could influence biochemical processes in living systems. It is intended as a primer for magneto-oncology researchers to assess whether observed magnetic-field-related biomedical effects may be explained by radical pair biochemistry. The article also notes the value of this framework for refining therapeutic protocols and for identifying potential experimental artifacts in oncology-related magnetic field research.

Sensation of electric fields in the Drosophila melanogaster larva

Research RF Safe Research Library Jan 1, 2025

This animal study reports that Drosophila melanogaster larvae can sense electric fields and exhibit robust electrotaxis toward the cathode in controlled environments. The authors identify head-tip sensory neurons required for this behavior and report calcium-imaging evidence that Gr66a-positive neurons encode field strength and orientation. The work supports electrosensation as a functional sensory modality in Drosophila larvae and demonstrates measurable neural and behavioral responses to electric fields under the studied conditions.

Electric and Magnetic Field Technologies in Agriculture: Plant Responses, Experimental Limitations, and Future Directions

Research RF Safe Research Library Jan 1, 2024

This narrative review discusses how electric and magnetic field technologies are applied in agriculture and how plants may respond. It proposes a model to explain potential mechanistic convergence between electric and magnetic field effects. The review highlights several suggested mechanisms, including membrane permeability changes, reactive oxygen species/antioxidant responses, altered ion transport, and DNA/gene expression changes.

Prospective cohort study on non-specific symptoms, cognitive, behavioral, sleep and mental health in relation to electronic media use and transportation noise among adolescents (HERMES): study protocol

Research RF Safe Research Library Jan 1, 2024

This protocol describes the third wave of the HERMES prospective adolescent cohort in Switzerland, with follow-up every four months and at one year. The study will assess electronic media use, modeled RF-EMF and transportation noise exposures, and a range of outcomes including cognition, behavior, sleep, mental health, and non-specific symptoms. A subsample will undergo personal RF-EMF measurements and accelerometer-based sleep/physical activity tracking.

The Impact of Mobile Phone Electromagnetic Waves on the Neurons and Blood Brain Barrier Integrity in the Chick Embryo

Research RF Safe Research Library Jan 1, 2024

This animal study exposed chick embryos to electromagnetic waves from a mobile phone and compared them with unexposed controls. Electron microscopy on days 10 and 15 reported neuronal and cerebellar cellular alterations in the exposed group, including features described as apoptosis and mitochondrial swelling. The authors also report compromised blood-brain barrier integrity and conclude the exposure adversely affects brain development.

Role of radio-frequency electromagnetic waves in causing oxidative stress

Research RF Safe Research Library Jan 1, 2024

This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in cardiomyocytes and hepatocytes. The authors conclude that radio-frequency electromagnetic waves can induce oxidative stress and mitochondrial damage in developing embryos.

The use of different exposure metrics in the research about the health impacts of electromagnetic fields

Research RF Safe Research Library Jan 1, 2024

This policy brief focuses on how RF-EMF exposure should be quantified in health research, emphasizing the role of near-field sources and proposing cumulative dose (J/kg/day) as a health-relevant metric. It reports mean cumulative dose estimates of 0.29 J/kg/day for the whole body and 0.81 J/kg/day for the brain. The brief notes established RF-EMF effects (heating, microwave hearing under highly pulsed radiation, and stimulation) and discusses indications of biological effects below thermal thresholds, while stating that improved metrics do not by themselves confirm harm.

Temporal Change of Outdoor Rf-Emf Levels Four in European Countries: A Microenvironmental Measurement Study

Research RF Safe Research Library Jan 1, 2024

This microenvironmental measurement study assessed temporal trends in outdoor RF-EMF exposure from 2016 to 2023 in four European countries using repeated walking-route measurements with exposimeters. The abstract reports that data did not suggest significant changes in mobile base station (downlink) exposure over time and that trends were not consistent across individual microenvironments. Reported median downlink exposure values varied by country and year but did not indicate an overall increase despite higher mobile data traffic.

Effect of Repeated Exposure to Complexly Organized Electromagnetic Radiation on the Rat Behavior in the "Open Field" Test

Research RF Safe Research Library Jan 1, 2024

This animal study examined repeated pulsed-modulated RF exposure (1–4 GHz; total pulse power density 300 μW/cm2) in male and female Wistar rats and assessed behavior using the open field test. The abstract reports stress reactions and long-term memory impairment in some rats, with females described as more sensitive than males. Reported effects were transient, with behavior returning to baseline within 1.5–2 months after exposure stopped. The authors suggest potential concern for constant exposure scenarios, though this is not directly evaluated in humans here.

A Decision Support System for Managing Health Symptoms of Living Near Mobile Phone Base Stations

Research RF Safe Research Library Jan 1, 2024

This analytical study evaluated machine learning models (SVM and Random Forest) to predict health symptoms in adults living near mobile phone base stations. The SVM model reportedly achieved high predictive performance for headache, sleep disturbance, dizziness, vertigo, and fatigue, and outperformed Random Forest and prior models. The abstract concludes that proximity to base stations is connected with increased prevalence of several symptoms and emphasizes distance, age, and duration of residence as key predictors.

The Systematic Review on RF-EMF Exposure and Cancer by Karipidis et al. (2024) has Serious Flaws that Undermine the Validity of the Study's Conclusions

Research RF Safe Research Library Jan 1, 2024

This letter critiques the WHO-sponsored systematic review by Karipidis et al. (2024) on RF-EMF exposure and cancer risk. The authors argue the review has serious methodological and interpretative flaws, including issues with study selection and data analysis. They contend that the review’s conclusion of "no clear evidence" may be misleading and should not be used as a basis for health policy or safety guidelines.

Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data

Research RF Safe Research Library Jan 1, 2024

This animal study examined whether continuous prenatal exposure to 2450 MHz radiofrequency radiation (simulating Wi‑Fi) affects thyroid tissue in rat offspring at 6 months. The exposed group showed significantly increased mononuclear cell infiltration and vascular congestion in thyroid histology. TUNEL-positive cell percentage and H2A.X antibody levels did not differ significantly between groups.

Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment

Research RF Safe Research Library Jan 1, 2024

Moon et al. (2024) report a systematic review and meta-analysis on cellular phone RF-EMR and brain tumor risk. The abstract summary states elevated risks for three brain tumor types in analyses considering ipsilateral (same-side) phone use and reports increased risk with heavy and long-term use. The text also highlights disagreement with the 2024 WHO review and raises methodological concerns about WHO conclusions.

The effects of radiofrequency exposure on male fertility: A systematic review of human observational studies with dose-response meta-analysis (SR 3)

Research RF Safe Research Library Jan 1, 2024

This systematic review and dose-response meta-analysis synthesizes human observational studies on radiofrequency EMF exposure and male fertility outcomes. It reports evidence of an association between RF exposure and poorer sperm parameters, including reduced quality, motility, and viability. The authors frame the findings as consistent with potential reproductive health risks and call for continued risk assessment and guideline development.

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