Effects of 2.45 GHz microwaves on meiotic chromosomes of male CBA/CAY mice.

PAPER pubmed The Journal of heredity 1985 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.1093/oxfordjournals.jhered.a110027 PMID: 3980975 Evidence Lab

Abstract

Male CBA/CAY mice were exposed daily (6 days a week) for 30 minutes in an environmentally controlled waveguide to continuous 2.45 GHz microwave radiation for 2 weeks at average whole body absorbed dose rates of 0.05, 0.5, 10, and 20 mW/g. Shan exposed animals served as controls. Chain translocations were observed at diakinesis at metaphase I in microwave exposed animals. The yield of translocations increased with exposure, and varied nonlinearly with dose rate. An increase in incidence of univalents was seen after exposure at 10 and 20 mW/g. The findings are interpreted to indicate interference with normal spermatogenesis during the exposure period.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Male CBA/CAY mice

Sample size

—

Exposure

microwave · 2450 MHz · 30 minutes daily (6 days/week) for 2 weeks

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Male mice exposed to continuous 2.45 GHz microwaves showed chain translocations at diakinesis/metaphase I; translocation yield increased with exposure and varied nonlinearly with dose rate. Increased incidence of univalents was reported after exposure at 10 and 20 mW/g.

Outcomes measured

Meiotic chromosome abnormalities (chain translocations at diakinesis/metaphase I)
Incidence of univalents
Spermatogenesis interference (interpretation)

Limitations

Sample size not reported in abstract
Exposure metric reported as absorbed dose rate (mW/g) without explicit SAR conversion in W/kg
Details on randomization/blinding and statistical methods not provided in abstract

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "30 minutes daily (6 days/week) for 2 weeks"
    },
    "population": "Male CBA/CAY mice",
    "sample_size": null,
    "outcomes": [
        "Meiotic chromosome abnormalities (chain translocations at diakinesis/metaphase I)",
        "Incidence of univalents",
        "Spermatogenesis interference (interpretation)"
    ],
    "main_findings": "Male mice exposed to continuous 2.45 GHz microwaves showed chain translocations at diakinesis/metaphase I; translocation yield increased with exposure and varied nonlinearly with dose rate. Increased incidence of univalents was reported after exposure at 10 and 20 mW/g.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Exposure metric reported as absorbed dose rate (mW/g) without explicit SAR conversion in W/kg",
        "Details on randomization/blinding and statistical methods not provided in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2.45 GHz",
        "microwave radiation",
        "mouse",
        "meiotic chromosomes",
        "chain translocations",
        "univalents",
        "spermatogenesis",
        "waveguide",
        "absorbed dose rate"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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