Effects of 2450 MHz microwave radiation during the gestational period on the postnatal hematology of rats.

Abstract

Pregnant Sprague-Dawley rats were exposed to 2.45 GHz CW radiation for 3 h daily from day 4 through day 20 of pregnancy at an average power density of 10.3 mW/cm2. At 2, 10, 20, and 30 d postpartum, several aspects of peripheral blood hematology of male and female pups were examined. No effects were noted on pregnancy rate or litter size; however, pup weight was reduced. Also, the white blood cell numbers were lower in male and female pups exposed to microwave radiation and the differential cell counts were altered in the female pups at 10 d postpartum. At 30 d of age, no differences were noted between the sham and exposed pups for any of the hematologic variables examined.

AI evidence extraction

Main findings

Gestational exposure to 2.45 GHz continuous-wave radiation (average power density 10.3 mW/cm2) did not affect pregnancy rate or litter size, but pup weight was reduced. White blood cell numbers were lower in exposed male and female pups, and differential cell counts were altered in female pups at 10 days postpartum. By 30 days postpartum, no differences were observed between sham and exposed pups for hematologic variables examined.

Outcomes measured

• pregnancy rate
• litter size
• pup weight
• white blood cell count
• differential cell counts
• peripheral blood hematology (multiple variables)

Limitations

• Sample size not reported in abstract.
• SAR and dosimetry beyond average power density not reported in abstract.
• Hematologic effects appeared transient (no differences at 30 days postpartum).

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "3 h daily from gestation day 4 through day 20"
    },
    "population": "Pregnant Sprague-Dawley rats and their male and female pups",
    "sample_size": null,
    "outcomes": [
        "pregnancy rate",
        "litter size",
        "pup weight",
        "white blood cell count",
        "differential cell counts",
        "peripheral blood hematology (multiple variables)"
    ],
    "main_findings": "Gestational exposure to 2.45 GHz continuous-wave radiation (average power density 10.3 mW/cm2) did not affect pregnancy rate or litter size, but pup weight was reduced. White blood cell numbers were lower in exposed male and female pups, and differential cell counts were altered in female pups at 10 days postpartum. By 30 days postpartum, no differences were observed between sham and exposed pups for hematologic variables examined.",
    "effect_direction": "mixed",
    "limitations": [
        "Sample size not reported in abstract.",
        "SAR and dosimetry beyond average power density not reported in abstract.",
        "Hematologic effects appeared transient (no differences at 30 days postpartum)."
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2.45 GHz",
        "2450 MHz",
        "microwave radiation",
        "continuous wave",
        "gestational exposure",
        "Sprague-Dawley rats",
        "postnatal",
        "hematology",
        "white blood cells",
        "pup weight"
    ],
    "suggested_hubs": []
}

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