Sperm count and sperm abnormality in male mice after exposure to 2.45 GHz microwave radiation.

PAPER pubmed Mutation research 1983 Animal study Effect: harm Evidence: Low

Read original paper → DOI: 10.1016/0165-7992(83)90054-4 PMID: 6656806 Evidence Lab

Abstract

Adult male mice had the posterior halves of their bodies exposed at 44 W/kg in a waveguide system to 2.45 GHz microwave radiation for 30 min. They were killed sequentially over 10 weeks and assessed for decreased sperm count and abnormal sperm morphology. The response in each assay was maximal 2-4 weeks after the exposure. This corresponds to microwaves having their greatest effect on spermatids and spermatocytes. Male fertility, assessed as the proportion of normal sperm per epididymis, was compared with results of an earlier study on dominant lethality. It is concluded that reduced male fertility correlates well with reduced pregnancy rate but less well with pre-implantation survival. Whilst microwaves clearly induced abnormally shaped sperm, those which achieved fertilization cannot have possessed a dominant mutation which would result in the post-implantation death of the embryo.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

adult male mice

Sample size

—

Exposure

microwave · 2450 MHz · 44 W/kg · 30 minutes

Evidence strength

Low

Confidence: 60% · Peer-reviewed: yes

Main findings

Exposure to 2.45 GHz microwaves at 44 W/kg for 30 minutes caused maximal decreases in sperm count and increased abnormal sperm morphology 2-4 weeks post-exposure. Reduced male fertility correlated with reduced pregnancy rate but less with pre-implantation survival. Abnormally shaped sperm were induced, but fertilizing sperm did not carry dominant mutations causing embryo death.

Outcomes measured

sperm count
sperm morphology abnormalities
male fertility (proportion of normal sperm)

Limitations

sample size not reported
only one exposure duration and intensity studied
study conducted in mice, limiting direct human applicability

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": 44,
        "duration": "30 minutes"
    },
    "population": "adult male mice",
    "sample_size": null,
    "outcomes": [
        "sperm count",
        "sperm morphology abnormalities",
        "male fertility (proportion of normal sperm)"
    ],
    "main_findings": "Exposure to 2.45 GHz microwaves at 44 W/kg for 30 minutes caused maximal decreases in sperm count and increased abnormal sperm morphology 2-4 weeks post-exposure. Reduced male fertility correlated with reduced pregnancy rate but less with pre-implantation survival. Abnormally shaped sperm were induced, but fertilizing sperm did not carry dominant mutations causing embryo death.",
    "effect_direction": "harm",
    "limitations": [
        "sample size not reported",
        "only one exposure duration and intensity studied",
        "study conducted in mice, limiting direct human applicability"
    ],
    "evidence_strength": "low",
    "confidence": 0.59999999999999997779553950749686919152736663818359375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "microwave radiation",
        "2.45 GHz",
        "sperm count",
        "sperm morphology",
        "male fertility",
        "mouse",
        "reproductive toxicity"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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