No clastogenic effect from in vitro microwave irradiation of G0 human lymphocytes.

PAPER pubmed International journal of radiation biology and related studies in physics, chemistry, and medicine 1984 In vitro study Effect: no_effect Evidence: Low

Read original paper → DOI: 10.1080/09553008414551211 PMID: 6332088 Evidence Lab

Abstract

Specimens of human blood were exposed at specific energy absorption rates of 104 or 193 W kg-1 to 2.45 GHz microwave radiation at temperatures below 36 degrees C. Cultured lymphocytes were examined for induced unstable chromosome and chromatid aberrations and sister chromatid exchanges. The amount of chromosome damage observed did not exceed that found in controls.

AI evidence extraction

At a glance

Study type

In vitro study

Effect direction

no_effect

Population

G0 human lymphocytes (from human blood specimens)

Sample size

—

Exposure

microwave · 2450 MHz

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Human blood specimens exposed to 2.45 GHz microwave radiation at specific energy absorption rates of 104 or 193 W/kg (below 36°C) showed chromosome damage that did not exceed control levels, including unstable chromosome/chromatid aberrations and sister chromatid exchanges.

Outcomes measured

unstable chromosome aberrations
chromatid aberrations
sister chromatid exchanges

Limitations

Sample size not reported in abstract.
Exposure duration not reported in abstract.
Only in vitro endpoints assessed; generalizability to in vivo outcomes not addressed in abstract.

View raw extracted JSON

{
    "study_type": "in_vitro",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": null
    },
    "population": "G0 human lymphocytes (from human blood specimens)",
    "sample_size": null,
    "outcomes": [
        "unstable chromosome aberrations",
        "chromatid aberrations",
        "sister chromatid exchanges"
    ],
    "main_findings": "Human blood specimens exposed to 2.45 GHz microwave radiation at specific energy absorption rates of 104 or 193 W/kg (below 36°C) showed chromosome damage that did not exceed control levels, including unstable chromosome/chromatid aberrations and sister chromatid exchanges.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in abstract.",
        "Exposure duration not reported in abstract.",
        "Only in vitro endpoints assessed; generalizability to in vivo outcomes not addressed in abstract."
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "in vitro",
        "microwave",
        "2.45 GHz",
        "specific energy absorption rate",
        "SAR",
        "human lymphocytes",
        "chromosome aberrations",
        "chromatid aberrations",
        "sister chromatid exchanges",
        "clastogenic"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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