Effect of 2450 MHz microwave radiation on hematopoiesis of pregnant mice.

PAPER pubmed Radiation research 1984 Animal study Effect: no_effect Evidence: Low

Read original paper → PMID: 6494447 Evidence Lab

Abstract

In this study, the influence of 2450 MHz CW microwave radiation on hematopoiesis in pregnant mice was examined. Dams (mice CD-1 strain) were irradiated during Days 1-6 or 6-15 of pregnancy. The animals were irradiated for a total of 8 hr per day (two 4-hr exposures in 9 hr) at an average power density of 30 mW/cm2. Peripheral blood and bone marrow samples were obtained on Day 18 of pregnancy. The total leukocyte and differential leukocyte counts of peripheral blood samples were not affected by either exposure regimen. In addition, no effects were noted in either the erythroid or myeloid mitotic indices of bone marrow samples. Exposure of pregnant mice to microwave radiation under the conditions of these experiments had no effects on the investigated aspects of hematopoiesis.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

no_effect

Population

Pregnant CD-1 strain mice (dams)

Sample size

—

Exposure

microwave · 2450 MHz · 8 hr/day (two 4-hr exposures in 9 hr) during gestation days 1–6 or 6–15

Evidence strength

Low

Confidence: 78% · Peer-reviewed: yes

Main findings

Pregnant mice exposed to 2450 MHz continuous-wave microwave radiation at an average power density of 30 mW/cm2 for 8 hr/day during gestation days 1–6 or 6–15 showed no changes in peripheral blood total or differential leukocyte counts on day 18 of pregnancy. No effects were observed in erythroid or myeloid mitotic indices in bone marrow.

Outcomes measured

Peripheral blood total leukocyte count
Peripheral blood differential leukocyte count
Bone marrow erythroid mitotic index
Bone marrow myeloid mitotic index

Limitations

Sample size not reported in the abstract
Specific dosimetry beyond average power density (e.g., SAR) not reported in the abstract
Only selected hematopoiesis endpoints assessed and measured at a single time point (day 18)

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": null,
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "8 hr/day (two 4-hr exposures in 9 hr) during gestation days 1–6 or 6–15"
    },
    "population": "Pregnant CD-1 strain mice (dams)",
    "sample_size": null,
    "outcomes": [
        "Peripheral blood total leukocyte count",
        "Peripheral blood differential leukocyte count",
        "Bone marrow erythroid mitotic index",
        "Bone marrow myeloid mitotic index"
    ],
    "main_findings": "Pregnant mice exposed to 2450 MHz continuous-wave microwave radiation at an average power density of 30 mW/cm2 for 8 hr/day during gestation days 1–6 or 6–15 showed no changes in peripheral blood total or differential leukocyte counts on day 18 of pregnancy. No effects were observed in erythroid or myeloid mitotic indices in bone marrow.",
    "effect_direction": "no_effect",
    "limitations": [
        "Sample size not reported in the abstract",
        "Specific dosimetry beyond average power density (e.g., SAR) not reported in the abstract",
        "Only selected hematopoiesis endpoints assessed and measured at a single time point (day 18)"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2450 MHz",
        "microwave radiation",
        "continuous wave",
        "pregnancy",
        "mice",
        "hematopoiesis",
        "bone marrow",
        "leukocyte count",
        "power density 30 mW/cm2"
    ],
    "suggested_hubs": []
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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