[FTIR spectra investigation of rat sensitive tissues exposure to ELF-EMF].

PAPER pubmed Guang pu xue yu guang pu fen xi = Guang pu 2012 Animal study Effect: harm Evidence: Low

Read original paper → PMID: 22827052 Evidence Lab

Abstract

Nonthermal effects of extremely low frequency electromagnetic fields (ELF-EMF) are related to changes in the microstructure of biological tissues after exposure to electromagnetic radiation. Fourier transform infrared spectroscopy (FTIR) analysis method can effectively study the mechanisms of biological effects of electromagnetic radiation. The present paper studies the characteristics of sensitive tissues of rat after ELF-EMF exposure. FTIR analysis of sensitive tissues of control group and experimental group showed that 50 Hz, 0.75 mT ELF-EMF exposure for 20 days can affect molecular level of the rat testis, blood and brain. Experimental results show that regular changes in absorption peak positions and intensity in the spectra of sensitive tissue may be caused by exposure to ELF-EMF, therefore, Fourier transform infrared spectroscopy is an effective means to study mechanism of biological effects of electromagnetic fields.

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

harm

Population

Rats

Sample size

—

Exposure

ELF · 20 days

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

FTIR analysis comparing control vs exposed rats indicated that 50 Hz, 0.75 mT ELF-EMF exposure for 20 days was associated with changes in absorption peak positions and intensities in spectra from rat testis, blood, and brain, interpreted as molecular-level effects.

Outcomes measured

FTIR spectral changes in rat sensitive tissues (testis, blood, brain)
Molecular-level changes inferred from absorption peak position/intensity changes

Limitations

Sample size not reported in abstract
Specific exposure regimen details beyond frequency, field strength, and duration not described (e.g., daily exposure time)
Outcomes are spectroscopic/molecular markers; no functional or clinical endpoints reported
Causality and biological significance of spectral changes not established in abstract

Suggested hubs

occupational-exposure (0.2)
Study involves ELF exposure parameters (50 Hz) relevant to power-frequency fields, though no occupational setting is described.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "ELF",
        "source": null,
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "20 days"
    },
    "population": "Rats",
    "sample_size": null,
    "outcomes": [
        "FTIR spectral changes in rat sensitive tissues (testis, blood, brain)",
        "Molecular-level changes inferred from absorption peak position/intensity changes"
    ],
    "main_findings": "FTIR analysis comparing control vs exposed rats indicated that 50 Hz, 0.75 mT ELF-EMF exposure for 20 days was associated with changes in absorption peak positions and intensities in spectra from rat testis, blood, and brain, interpreted as molecular-level effects.",
    "effect_direction": "harm",
    "limitations": [
        "Sample size not reported in abstract",
        "Specific exposure regimen details beyond frequency, field strength, and duration not described (e.g., daily exposure time)",
        "Outcomes are spectroscopic/molecular markers; no functional or clinical endpoints reported",
        "Causality and biological significance of spectral changes not established in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "ELF-EMF",
        "50 Hz",
        "0.75 mT",
        "rats",
        "FTIR",
        "testis",
        "blood",
        "brain",
        "nonthermal effects",
        "spectroscopy"
    ],
    "suggested_hubs": [
        {
            "slug": "occupational-exposure",
            "weight": 0.200000000000000011102230246251565404236316680908203125,
            "reason": "Study involves ELF exposure parameters (50 Hz) relevant to power-frequency fields, though no occupational setting is described."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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