Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During

PAPER manual 2024 Animal study Effect: mixed Evidence: Low

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Abstract

Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data Ozyilmaz C, Oktay MF, Dasdag S, Ulukaya E, Genel ME, Tansuker HD, Emre F, Yeğin K. Evaluation of the Thyroids of Offsprings Exposed to 2450 MHz Radiofrequency Radiation During Pregnancy: A Sixth Month Data. Journal of International Dental & Medical Research, 2024, 17(2): 925-930. Abstract This study aimed to determine whether the exposure to radiofrequency emitted by wireless internet providers (2450 MHz) throughout the day during rats’ pregnancy causes a problem in the thyroid tissues of their offspring. The pregnant rats in the experimental group were exposed to radiofrequency radiation (RFR) (24 hours/day) at a 2450 MHz frequency in pulse wave mode with 1 W output strength by a generator simulating Wi-Fi waves. The offspring in the control and experimental groups were randomized selected (n:8). At the end of the sixth month, the thyroid tissues were removed and evaluated histopathologically and biochemically. Mann‒Whitney U-tests and T-tests were used for statistical analysis. The threshold for statistical significance was p <0.05. There was a significant difference in mononuclear cell infiltration (p=0.03) and vascular increase in congestion (p<0.001). There was no difference in the TUNEL-positive cell percentage (p=0.62) and H2A.X antibody levels (p=0.68) between the rats in the control and experimental groups. In this study, 2450 MHz RFR exposure during the prenatal period did not cause a statistically significant difference in terms of H2A.X levels and TUNEL-positive cell percentages in the thyroid tissue of rats. Open access paper: jidmr.com M24_3112_Suleyman_DASDAG_Turkey-Exp-2.pdf

AI evidence extraction

At a glance

Study type

Animal study

Effect direction

mixed

Population

Pregnant rats and their offspring (thyroid tissue assessed at 6 months)

Sample size

Exposure

microwave wi-fi · 2450 MHz · 24 hours/day during pregnancy (prenatal exposure)

Evidence strength

Low

Confidence: 74% · Peer-reviewed: yes

Main findings

Offspring thyroid tissue at 6 months showed significant differences for mononuclear cell infiltration (p=0.03) and vascular increase in congestion (p<0.001) between exposed and control groups. No statistically significant differences were reported for TUNEL-positive cell percentage (p=0.62) or H2A.X antibody levels (p=0.68).

Outcomes measured

Thyroid histopathology (mononuclear cell infiltration)
Thyroid histopathology (vascular increase in congestion)
TUNEL-positive cell percentage in thyroid tissue
H2A.X antibody levels in thyroid tissue

Limitations

SAR not reported
Exposure described as 1 W output strength but field levels at animals not reported
Small sample size (n:8)
Details on randomization/blinding not described in abstract

Suggested hubs

school-wi-fi (0.55)
Exposure source described as wireless internet provider / Wi-Fi at 2450 MHz.

View raw extracted JSON

{
    "study_type": "animal",
    "exposure": {
        "band": "microwave",
        "source": "wi-fi",
        "frequency_mhz": 2450,
        "sar_wkg": null,
        "duration": "24 hours/day during pregnancy (prenatal exposure)"
    },
    "population": "Pregnant rats and their offspring (thyroid tissue assessed at 6 months)",
    "sample_size": 8,
    "outcomes": [
        "Thyroid histopathology (mononuclear cell infiltration)",
        "Thyroid histopathology (vascular increase in congestion)",
        "TUNEL-positive cell percentage in thyroid tissue",
        "H2A.X antibody levels in thyroid tissue"
    ],
    "main_findings": "Offspring thyroid tissue at 6 months showed significant differences for mononuclear cell infiltration (p=0.03) and vascular increase in congestion (p<0.001) between exposed and control groups. No statistically significant differences were reported for TUNEL-positive cell percentage (p=0.62) or H2A.X antibody levels (p=0.68).",
    "effect_direction": "mixed",
    "limitations": [
        "SAR not reported",
        "Exposure described as 1 W output strength but field levels at animals not reported",
        "Small sample size (n:8)",
        "Details on randomization/blinding not described in abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7399999999999999911182158029987476766109466552734375,
    "peer_reviewed_likely": "yes",
    "keywords": [
        "2450 MHz",
        "radiofrequency radiation",
        "Wi-Fi",
        "prenatal exposure",
        "pregnancy",
        "rat offspring",
        "thyroid",
        "histopathology",
        "TUNEL",
        "H2A.X"
    ],
    "suggested_hubs": [
        {
            "slug": "school-wi-fi",
            "weight": 0.5500000000000000444089209850062616169452667236328125,
            "reason": "Exposure source described as wireless internet provider / Wi-Fi at 2450 MHz."
        }
    ]
}

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AI-extracted fields are generated from the abstract/metadata and may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.

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