Effects of coenzyme Q10 on sperm parameters and pathological changes induced by Wi-Fi waves in the testicular tissue of rats

{
    "publication_year": 2025,
    "study_type": "animal",
    "exposure": {
        "band": "RF",
        "source": "wi-fi",
        "frequency_mhz": null,
        "sar_wkg": null,
        "duration": "7 hours/day for 2 months"
    },
    "population": "Rats",
    "sample_size": 20,
    "outcomes": [
        "Sperm concentration",
        "Sperm viability",
        "Sperm motility",
        "Serum testosterone",
        "Testicular pathology",
        "Epididymal pathology"
    ],
    "main_findings": "In a rat model, Wi‑Fi exposure was reported to be associated with negative changes in sperm parameters, serum testosterone, and testicular pathology. Coenzyme Q10 supplementation (150 mg/kg daily) during Wi‑Fi exposure was reported to improve sperm concentration, viability, and motility, increase serum testosterone, and reduce histopathological disruption of spermatogenesis compared with Wi‑Fi exposure alone.",
    "effect_direction": "harm",
    "limitations": [
        "Animal study; findings may not generalize to humans",
        "Small group sizes (n=5 per group)",
        "Wi‑Fi exposure characteristics (e.g., frequency, power/SAR) not reported in the abstract"
    ],
    "evidence_strength": "low",
    "confidence": 0.7800000000000000266453525910037569701671600341796875,
    "peer_reviewed_likely": "yes",
    "stance": "concern",
    "stance_confidence": 0.85999999999999998667732370449812151491641998291015625,
    "summary": "This animal study exposed rats to Wi‑Fi waves for 7 hours/day for 2 months and assessed sperm parameters, serum testosterone, and testicular/epididymal pathology, with and without coenzyme Q10 (CoQ10). The authors report that Wi‑Fi exposure was linked to worse sperm parameters, lower testosterone, and adverse testicular pathology. CoQ10 supplementation during exposure was reported to mitigate these changes compared with Wi‑Fi exposure alone.",
    "key_points": [
        "Twenty rats were allocated to four groups (Wi‑Fi-free control, Wi‑Fi exposure, Wi‑Fi exposure + CoQ10, and CoQ10 only).",
        "Wi‑Fi exposure was 7 hours per day for 2 months, but exposure metrics such as frequency and SAR were not provided in the abstract.",
        "Outcomes included sperm concentration, viability, motility, serum testosterone, and histopathology of testis and epididymis.",
        "Compared with the Wi‑Fi-only group, CoQ10 during Wi‑Fi exposure was reported to improve sperm concentration, viability, and motility.",
        "CoQ10 supplementation was reported to increase serum testosterone relative to Wi‑Fi-only exposure.",
        "Histopathology reportedly showed fewer seminiferous tubules with disrupted spermatogenesis in the CoQ10 + Wi‑Fi group than in the Wi‑Fi-only group.",
        "The authors conclude Wi‑Fi exposure negatively affected male reproductive measures in rats and that CoQ10 mitigated these effects."
    ],
    "categories": [
        "Reproductive Health",
        "Animal Studies",
        "Radiofrequency (RF)",
        "Wi-Fi"
    ],
    "tags": [
        "Coenzyme Q10",
        "Wi-Fi Exposure",
        "Radiofrequency Electromagnetic Fields",
        "Sperm Parameters",
        "Sperm Motility",
        "Sperm Viability",
        "Sperm Concentration",
        "Serum Testosterone",
        "Testicular Pathology",
        "Epididymis",
        "Male Reproductive Health",
        "Rat Model"
    ],
    "keywords": [
        "coenzyme Q10",
        "Wi-Fi exposure",
        "sperm parameters",
        "testicular pathology",
        "electromagnetic fields",
        "reproductive health",
        "rats"
    ],
    "suggested_hubs": [
        {
            "slug": "wifi",
            "weight": 0.9499999999999999555910790149937383830547332763671875,
            "reason": "Study examines biological effects of Wi‑Fi wave exposure in rats."
        }
    ],
    "social": {
        "tweet": "Rat study: Wi‑Fi exposure (7 h/day for 2 months) was reported to worsen sperm measures, testosterone, and testicular pathology; CoQ10 supplementation was reported to mitigate these effects. (Annals of Medicine & Surgery, 2025)",
        "facebook": "In a rat model, researchers reported that Wi‑Fi exposure (7 hours/day for 2 months) was associated with poorer sperm parameters, lower testosterone, and adverse testicular changes. Coenzyme Q10 supplementation was reported to improve sperm measures and reduce testicular pathology compared with Wi‑Fi exposure alone.",
        "linkedin": "Animal study (2025, Annals of Medicine & Surgery): Wi‑Fi exposure in rats (7 h/day for 2 months) was reported to negatively affect sperm parameters, serum testosterone, and testicular histopathology. Coenzyme Q10 supplementation during exposure was reported to mitigate these changes versus Wi‑Fi exposure alone."
    }
}

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