Peer-reviewed comments on NTP cellphone radiation study by Hardell and Carlberg

Abstract

Peer-reviewed comments on NTP cellphone radiation study by Hardell and Carlberg Hardell L, Carlberg M. Comments on the US National Toxicology Program technical reports on toxicology and carcinogenesis study in rats exposed to whole-body radiofrequency radiation at 900 MHz and in mice exposed to whole-body radiofrequency radiation at 1,900 MHz. International Journal of Oncology. Published Oct 24, 2018. doi.org Abstract During the use of handheld mobile and cordless phones, the brain is the main target of radiofrequency (RF) radiation. An increased risk of developing glioma and acoustic neuroma has been found in human epidemiological studies. Primarily based on these findings, the International Agency for Research on Cancer (IARC) at the World Health Organization (WHO) classified in May, 2011 RF radiation at the frequency range of 30 kHz-300 GHz as a 'possible' human carcinogen, Group 2B. A carcinogenic potential for RF radiation in animal studies was already published in 1982. This has been confirmed over the years, more recently in the Ramazzini Institute rat study. An increased incidence of glioma in the brain and malignant schwannoma in the heart was found in the US National Toxicology Program (NTP) study on rats and mice. The NTP final report is to be published; however, the extended reports are published on the internet for evaluation and are reviewed herein in more detail in relation to human epidemiological studies. Thus, the main aim of this study was to compare earlier human epidemiological studies with NTP findings, including a short review of animal studies. We conclude that there is clear evidence that RF radiation is a human carcinogen, causing glioma and vestibular schwannoma (acoustic neuroma). There is some evidence of an increased risk of developing thyroid cancer, and clear evidence that RF radiation is a multi-site carcinogen. Based on the Preamble to the IARC Monographs, RF radiation should be classified as carcinogenic to humans, Group 1. Abstract: spandidos-publications.com Open access paper: spandidos-publications.com

AI evidence extraction

Main findings

This paper provides comments and a comparative review of the US NTP radiofrequency radiation animal studies (rats at 900 MHz; mice at 1,900 MHz) in relation to earlier human epidemiological studies and other animal studies. The authors conclude there is clear evidence that RF radiation is a human carcinogen causing glioma and vestibular schwannoma, with some evidence for increased thyroid cancer risk, and argue RF radiation should be classified as IARC Group 1.

Outcomes measured

• glioma
• vestibular schwannoma (acoustic neuroma)
• malignant schwannoma in the heart
• thyroid cancer
• cancer (multi-site carcinogenicity)

Limitations

• This is a commentary/review rather than an original epidemiological or experimental study (no new primary data reported in the abstract).
• No methods for literature search, study selection, or risk-of-bias assessment are described in the provided abstract.

Suggested hubs

• who-icnirp (0.72)
  Discusses WHO/IARC classification of RF radiation and argues for reclassification to Group 1.

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    },
    "population": null,
    "sample_size": null,
    "outcomes": [
        "glioma",
        "vestibular schwannoma (acoustic neuroma)",
        "malignant schwannoma in the heart",
        "thyroid cancer",
        "cancer (multi-site carcinogenicity)"
    ],
    "main_findings": "This paper provides comments and a comparative review of the US NTP radiofrequency radiation animal studies (rats at 900 MHz; mice at 1,900 MHz) in relation to earlier human epidemiological studies and other animal studies. The authors conclude there is clear evidence that RF radiation is a human carcinogen causing glioma and vestibular schwannoma, with some evidence for increased thyroid cancer risk, and argue RF radiation should be classified as IARC Group 1.",
    "effect_direction": "harm",
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        "glioma",
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