Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring.
Research
RF Safe Research Library
Jan 1, 2024
This rat study examined prenatal stress, prenatal ELF-EMF exposure, and their combination on adult male offspring outcomes at postnatal day 90. Prenatal stress increased serum corticosterone but did not change spatial memory, while combined stress+ELF-EMF disrupted memory acquisition. ELF-EMF exposure was associated…
The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats.
Research
RF Safe Research Library
Jan 1, 2022
This animal study exposed 40 adult male rats to a 10 Hz (4 mT) extremely low-frequency electromagnetic field for 1 hour daily for either 7 or 30 days. The authors report improved spatial memory after prolonged (30-day) exposure, alongside increased hippocampal BDNF levels. They also note a significant body weight…
Evaluation of the neuroprotective effects of electromagnetic fields and coenzyme Q on hippocampal injury in mouse.
Research
RF Safe Research Library
Jan 1, 2019
This animal study tested whether 50 Hz EMF exposure and/or CoQ10 could protect against TMT-induced hippocampal injury in mature female mice. CoQ10 and CoQ10+EMF were associated with improved spatial memory and reduced histological markers of cell death, alongside increased antiapoptotic markers. EMF alone reportedly…
Microwave radiation leading to shrinkage of dendritic spines in hippocampal neurons mediated by SNK-SPAR pathway.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed Wistar rats to microwave radiation (30 mW/cm for 6 minutes, three times per week for six weeks) and assessed cognition, hippocampal dendritic spines, ultrastructure, and SNK-SPAR pathway molecules. The authors report impaired spatial learning and memory, dendritic spine loss/shrinkage, and…
From the Cover: 2.45-GHz Microwave Radiation Impairs Hippocampal Learning and Spatial Memory: Involvement of Local Stress Mechanism-Induced Suppression of iGluR/ERK/CREB Signaling.
Research
RF Safe Research Library
Jan 1, 2018
This mouse study examined low-level 2.45 GHz continuous-wave microwave exposure for 2 hours/day over 15, 30, or 60 days. The authors report impaired learning and spatial memory performance on an 8-arm radial maze after exposure. They also report increased corticosterone and stress/inflammatory-related markers with…
Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats
Research
RF Safe Research Library
Mar 19, 2015
This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…
2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism
Research
RF Safe Research Library
Jan 1, 2015
This animal study exposed male Swiss mice to 2.45 GHz continuous-wave microwave radiation for 2 hours/day over 15, 30, or 60 days. The authors report increased hippocampal oxidative/nitrosative stress and increased apoptosis in neuronal and nonneuronal hippocampal subfields. They also report duration-dependent…