EMF-induced mesenchymal stem cell migration is mediated by SOCE-dependent calcium influx and modulated by ROCK signaling.
Research
RF Safe Research Library
Jan 1, 2026
This in vitro study exposed rat bone marrow-derived mesenchymal stem cells to a 50 Hz, 5 mT sinusoidal EMF and assessed migration and signaling mechanisms. The authors report increased MSC migration that depended on extracellular Ca²⁺ influx and was abolished by SOCE inhibition, alongside increased Orai1 expression…
Effects of moderate static magnetic fields on voltage-gated potassium ion channels in sympathetic neuron-like PC12 cells
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined effects of moderate static magnetic field exposure on sympathetic neuron-like PC12 cells. The authors report a significant reduction in voltage-gated potassium (Kv) channel current density after 18 hours of exposure, with the reduction persisting after the field was removed. RNA…
Transcriptional response of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2024
This in vitro study exposed rat primary hippocampal neurons to 3.0 GHz continuous-wave RF-EMF under low-SAR (minimal heating) and high-SAR (thermal) conditions and measured transcriptional responses by RNA sequencing. Twenty genes were significantly upregulated only in the high-SAR condition associated with a ~3.6°C…
Global gene expression changes reflecting pleiotropic effects of Irpex lacteus induced by low--intensity electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2019
This laboratory study used RNA-seq to examine how low-intensity electromagnetic field (LI-EMF) exposure affects global gene expression in the fungus Irpex lacteus. Thousands of differentially expressed genes were reported immediately after exposure, with fewer changes after 3 h and 6 h recovery, and a subset of genes…