Archive

This systematic review assessed interventional preclinical and clinical studies of adjunctive non-ionizing magnetic or combined EMF therapies in dental implant surgery. Twelve studies were included, with most reporting improvements in implant stability and indicators of osteogenesis/osseointegration. Evidence for…

This in vitro study compared continuous versus intermittent 16 Hz ELF-PEMF exposure strategies in osteoprogenitor (SCP-1) cells. Intermittent exposure (10 min every 8 h) was reported to enhance cell numbers and osteogenic function relative to continuous daily exposure (30 min every 24 h). The authors report increased…

This study describes a magnetofection system using electromagnetic field (EMF) co-stimulation with iron oxide nanoparticles (IONPs) to deliver miR-21. The authors report increased transfection efficiency and promotion of osteogenesis and angiogenesis in BMSCs and HUVECs, with downstream application to…

This in vitro study developed magnetic electrospun nanofibers for bone regeneration and evaluated osteogenic and antibacterial properties. Functionalization with ATP and Mg increased mesenchymal stem cell adhesion, proliferation, and osteogenic marker readouts compared with unmodified fibers. The authors report that…

This in vitro and animal study evaluated whether extremely low frequency EMF exposure (1 mT, 45 Hz, 8 h/day) combined with Fe-based nanomagnetic particles enhances osteogenesis. The authors report no detectable cytotoxicity and increased osteogenic markers/proteins with combined NMP + EMF exposure, alongside…

This animal and in vitro study evaluated sinusoidal electromagnetic field (SEMF) exposure combined with VEGF in rat mesenchymal stem cells and in a rat cranial defect model using rBMSC-laden PCL/HA scaffolds. The authors report increased osteogenic and endothelial marker expression with SEMF and VEGF, with a slight…