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Filters: tag: Nitric Oxide Clear

Alleviation of Inflammatory Conditions Caused by Extremely Low-Frequency Electromagnetic Field Exposure by .

Research RF Safe Research Library Jan 1, 2025

This in vitro study exposed RAW 264.7 cells to extremely low-frequency electromagnetic fields (ELF-EMF) and evaluated inflammatory signaling and related endpoints. The authors report that ELF-EMF increased nitric oxide and pro-inflammatory cytokines and was associated with increased NF-κB translocation and NFAT2…

Sinusoidal Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Promotes Angiogenesis In Vitro.

Research RF Safe Research Library Jan 1, 2025

This in vitro/in ovo study examined whether extremely low-frequency electromagnetic stimulation (ELF-EMS; 13.5 mT at 10 and 60 Hz) activates angiogenic processes under homeostatic conditions. In human microvascular endothelial cells, ELF-EMS increased proliferation, migration/transmigration, and tube formation, with…

Investigating the effect of radiofrequency electromagnetic field exposure on molecular pathways related to insulin resistance and adipogenesis in zebrafish embryos - A pilot study without quantitative exposure metrics.

Research RF Safe Research Library Jan 1, 2024

This pilot animal study exposed zebrafish embryos to 900 MHz RF-EMF for 30 or 60 minutes per day until 96 hours post-fertilization and assessed gene expression and physiological endpoints. The authors report reduced expression of lepa, ins, and pparg, changes in oxidative stress markers consistent with increased…

Benign Effect of Extremely Low-Frequency Electromagnetic Field on Brain Plasticity Assessed by Nitric Oxide Metabolism during Poststroke Rehabilitation.

Research RF Safe Research Library Jan 1, 2017

This study assessed whether adding extremely low-frequency electromagnetic field (ELF-EMF) exposure to a 4-week poststroke rehabilitation program affects nitric oxide (NO)-related biomarkers and patient status. Forty-eight poststroke patients were assigned to ELF-EMF versus non-ELF-EMF rehabilitation, with the…

The expression of pluripotency and neuronal differentiation markers under the influence of electromagnetic field and nitric oxide.

Research RF Safe Research Library Jan 1, 2017

This in vitro study examined how 50 Hz low-frequency EMF and a nitric oxide donor (Deta-NO) affect stemness and neuronal differentiation markers in rat bone marrow mesenchymal stem cells. The authors report that high NO (1 mM) combined with EMF reduced stemness markers and increased neuronal differentiation markers,…

Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor

Research RF Safe Research Library Jan 1, 2016

This narrative review proposes that low-intensity microwave/lower-frequency EMFs activate plasma membrane calcium channels in animals, increasing intracellular calcium and triggering downstream signaling including oxidative stress pathways. It further suggests that EMF actions in terrestrial multicellular plants are…

Disordered redox metabolism of brain cells in rats exposed to low doses of ionizing radiation or UHF electromagnetic radiation.

Research RF Safe Research Library Jan 1, 2016

This animal study assessed redox-state changes in rat brain cells after long-term low-intensity ionizing radiation exposure or fractionated non-thermal UHF electromagnetic radiation. Both exposures were associated with decreased ubisemiquinone and increased NO-FeS-protein complexes, alongside increased mitochondrial…

Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effects

Research RF Safe Research Library Jan 1, 2013

This narrative review argues that non-thermal biological effects of extremely low and microwave frequency EMFs may be mediated by activation of voltage-gated calcium channels (VGCCs). It cites 23 studies in which VGCC blockers reportedly block or reduce diverse EMF effects and proposes downstream…

900 MHz radiofrequency-induced histopathologic changes and oxidative stress in rat endometrium: protection by vitamins E and C.

Research RF Safe Research Library Jan 1, 2007

This rat study examined 900 MHz radiofrequency exposure (30 min/day for 30 days) and reported biochemical and histopathologic changes in endometrial tissue consistent with oxidative stress and tissue injury. The abstract reports increased NO and MDA and decreased antioxidant enzyme activities (SOD, CAT, GSH-Px) in…

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