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Filters: tag: Morris Water Maze Clear

Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.

Research RF Safe Research Library Jan 1, 2024

This animal study examined 1850 MHz RF-EMF exposure (SAR 4.0 W/kg) in early postnatal mice and assessed synaptic and behavioral outcomes. The abstract reports reductions in dendritic spine maturation markers, decreases in PSD-95 puncta, inhibited neurite outgrowth, and downregulation of synapse-related genes in…

Effect of prenatal exposure to stress and extremely low-frequency electromagnetic field on hippocampal and serum BDNF levels in male adult rat offspring.

Research RF Safe Research Library Jan 1, 2024

This rat study examined prenatal stress, prenatal ELF-EMF exposure, and their combination on adult male offspring outcomes at postnatal day 90. Prenatal stress increased serum corticosterone but did not change spatial memory, while combined stress+ELF-EMF disrupted memory acquisition. ELF-EMF exposure was associated…

Lipoic acid inhibits cognitive impairment induced by multiple cell phones in young male rats: role of Sirt1 and Atg7 pathway.

Research RF Safe Research Library Jan 1, 2023

This animal study examined whether lipoic acid modifies cognitive and hippocampal effects in young male rats exposed to EMF emitted from multiple cell phones. The authors report improved learning performance but impaired long-term memory consolidation after EMF exposure, alongside changes in hippocampal…

Extremely low frequency electromagnetic fields promote cognitive function and hippocampal neurogenesis of rats with cerebral ischemia.

Research RF Safe Research Library Jan 1, 2021

This animal study evaluated whether ELF-EMF exposure affects recovery-related outcomes after cerebral ischemia in rats. Rats exposed to 50 Hz, 1 mT ELF-EMF for 2 hours daily over 28 days showed better Morris water maze performance than untreated rats. The study also reports increased hippocampal neurogenesis markers…

Evaluation of the neuroprotective effects of electromagnetic fields and coenzyme Q on hippocampal injury in mouse.

Research RF Safe Research Library Jan 1, 2019

This animal study tested whether 50 Hz EMF exposure and/or CoQ10 could protect against TMT-induced hippocampal injury in mature female mice. CoQ10 and CoQ10+EMF were associated with improved spatial memory and reduced histological markers of cell death, alongside increased antiapoptotic markers. EMF alone reportedly…

Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats

Research RF Safe Research Library Mar 19, 2015

This animal study exposed 108 male Sprague-Dawley rats to 900 MHz EMF (1 mW/cm2) or sham for 14 or 28 days (3 h/day). The authors report that 28-day exposure was associated with impaired spatial memory, BBB permeability damage, and ultrastructural changes in hippocampus and cortex. They also report increased mkp-1…

2.45 GHz Microwave Radiation Impairs Learning and Spatial Memory via Oxidative/Nitrosative Stress Induced p53-Dependent/Independent Hippocampal Apoptosis: Molecular Basis and Underlying Mechanism

Research RF Safe Research Library Jan 1, 2015

This animal study exposed male Swiss mice to 2.45 GHz continuous-wave microwave radiation for 2 hours/day over 15, 30, or 60 days. The authors report increased hippocampal oxidative/nitrosative stress and increased apoptosis in neuronal and nonneuronal hippocampal subfields. They also report duration-dependent…

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