From particulates to pathways: environmental exposures and their impact on Alzheimer's disease
Research
RF Safe Research Library
Jan 1, 2025
This review discusses how environmental exposures across air, water, and soil pollutants may influence Alzheimer's disease (AD) onset and progression. It highlights EMFs as a potential aggravating factor, reporting associations with oxidative stress, inflammation, calcium dysregulation, and accelerated amyloid-beta…
A Novel Design of a Portable Birdcage via Meander Line Antenna (MLA) to Lower Beta Amyloid (Aβ) in Alzheimer's Disease.
Research
RF Safe Research Library
Jan 1, 2025
This translational engineering paper describes a portable RF birdcage/meander line antenna concept for repeated electromagnetic field stimulation at 64 MHz aimed at lowering amyloid-beta in Alzheimer’s disease. The abstract reports prior in vitro findings in primary human brain cultures showing reduced secreted Aβ-42…
EMF Antenna Exposure on a Multilayer Human Head Simulation for Alzheimer Disease Treatments.
Research
RF Safe Research Library
Jan 1, 2022
This study uses HFSS/EMPro simulations to model a 64 MHz antenna exposure on a multilayer human head to match parameters previously used in neuronal culture experiments. The simulations report achieving up to 0.6 W/kg maximum SAR and approximately 0.4–0.6 W/kg across head layers with a 1 A peak current pulse. The…
Electromagnetic Field in Alzheimer's Disease: A Literature Review of Recent Preclinical and Clinical Studies.
Research
RF Safe Research Library
Jan 1, 2020
This literature review summarizes recent preclinical and clinical research on electromagnetic fields (EMF) in relation to Alzheimer's disease (AD). It describes AD pathology involving amyloid-beta accumulation and tau hyperphosphorylation and notes limitations of current symptomatic treatments. The authors report…
Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…