Archive

This in vitro study exposed rat bone marrow-derived mesenchymal stem cells to a 50 Hz, 5 mT sinusoidal EMF and assessed migration and signaling mechanisms. The authors report increased MSC migration that depended on extracellular Ca²⁺ influx and was abolished by SOCE inhibition, alongside increased Orai1 expression…

This in vitro study exposed human umbilical cord blood lymphocytes to a sinusoidal sweeping-frequency ELF magnetic field (3–26 Hz) for 48 hours at amplitudes from 6 to 24 μT. It reports no statistically significant effects on DNA damage/repair foci or apoptosis measures overall. A non-significant trend at 8 μT showed…

This in vitro/in ovo study examined whether extremely low-frequency electromagnetic stimulation (ELF-EMS; 13.5 mT at 10 and 60 Hz) activates angiogenic processes under homeostatic conditions. In human microvascular endothelial cells, ELF-EMS increased proliferation, migration/transmigration, and tube formation, with…

This in vitro study tested a 50 Hz, 1.3 mT sinusoidal electromagnetic field applied for 15 or 30 minutes to ARPE-19 retinal pigment epithelial cells and RGC-5 retinal ganglion cells. The authors report improved proliferative and migratory capacity after EMF exposure, alongside increased HO-1 and altered RNA…

This animal feasibility study evaluated whether real-time measured, targeted sinusoidal EMF stimulation could normalize traumatic brain injury (TBI)-related changes in neuronally generated EMF patterns. In one Yucatan miniswine with controlled cortical impact, AI modeling distinguished pre-injury, post-injury, and…

This in vitro and rat study evaluated sinusoidal electromagnetic field (EMF) treatment of bone marrow mesenchymal stem cells (BMSCs) seeded on 3D-printed scaffolds for repairing critical-sized calvarial defects. The authors report that EMF-treated cell scaffolds accelerated bone defect repair in rats.…

This in vitro and rat-model study evaluated sinusoidal low-frequency EMF combined with a PCL/nHA scaffold seeded with BMSCs for intervertebral fusion. The authors report enhanced osteogenic differentiation of BMSCs and pro-osteogenic effects of conditioned medium from EMF-treated BMSCs, with suggested involvement of…

This animal and in vitro study evaluated sinusoidal electromagnetic field (SEMF) exposure combined with VEGF in rat mesenchymal stem cells and in a rat cranial defect model using rBMSC-laden PCL/HA scaffolds. The authors report increased osteogenic and endothelial marker expression with SEMF and VEGF, with a slight…

This article describes a signal-processing/measurement concept in pulsed magnetic resonance: achieving phase cycling through sinusoidal magnetic field modulation rather than changing pulse phases. The abstract states that modulation parameters can control spin precession phases, enabling separation of unwanted…

This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…

This randomized animal experiment exposed 32 young female rats to 1.8 mT sinusoidal alternating electromagnetic fields at 10, 25, or 40 Hz for 90 minutes per day. The 10 Hz and 40 Hz groups had higher BMD and improved femur and lumbar vertebra biomechanical properties compared with controls, and micro-CT suggested…

This paper presents a two-compartment computational model of CA3 pyramidal neurons to investigate how extracellular electric fields influence neuronal behavior via ephaptic transmission. The model is matched to subthreshold experimental responses at rest and used to analyze how DC and sinusoidal fields affect…

This in vitro study exposed newborn rat calvarial osteoblasts to 50 Hz sinusoidal electromagnetic fields at 1.8 mT for different daily exposure times (0.5–3.0 h). The authors report inhibited osteoblast proliferation at longer exposure times, alongside increased differentiation markers (ALP activity) and…

This in vitro study examined whether extremely low-frequency magnetic fields affect chondrogenic differentiation of human mesenchymal stem cells in pellet culture. Cells exposed for 3 weeks to a homogeneous sinusoidal 5 mT magnetic field showed increased collagen type II expression (significant at passage 6) and…