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Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.

Research RF Safe Research Library Jan 1, 2019

This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…

T-Cell Differentiation to T Helper 9 Phenotype is Elevated by Extremely Low-Frequency Electromagnetic Fields Via Induction of IL-2 Signaling.

Research RF Safe Research Library Jan 1, 2019

This in vitro study examined 60 Hz extremely low-frequency EMF exposure (0.8 mT) on CD4 T cells under Th9-polarizing conditions. The authors report increased Th9-associated responses including IL-9 secretion, transcription factor changes (including early GATA3), and increased STAT5/STAT6 phosphorylation alongside…

Evaluation of the Validity of a Nonlinear J-Shaped Dose-Response Relationship in Cancers Induced by Exposure to Radiofrequency Electromagnetic Fields.

Research RF Safe Research Library Jan 1, 2019

This review discusses the controversial evidence on mobile phone RF-EMF exposure and brain cancer. The authors argue that exposure magnitude may be a key factor contributing to inconsistent findings. They discuss evidence supporting a nonlinear J-shaped dose-response relationship for RF-EMF-related carcinogenesis.

[The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones - 24-h monitoring of ECG and blood pressure].

Research RF Safe Research Library Jan 1, 2019

In a worker sample undergoing 24-hour ECG and ambulatory blood pressure monitoring, higher self-reported daily mobile phone use (>60 minutes) was associated with higher systolic blood pressure in office measurement and at night. Higher occupational stress was associated with higher systolic and diastolic blood…

Residential exposure to ultra high frequency electromagnetic fields emitted by Global System for Mobile (GSM) antennas and amyotrophic lateral sclerosis incidence: A geo-epidemiological population-based study.

Research RF Safe Research Library Jan 1, 2019

This geo-epidemiological population-based study in Limousin (France) assessed modeled residential UHF-EMF exposure from GSM antennas and ALS incidence from 2000–2012. The authors report a statistically significant exposure–response trend and higher ALS risk in the highest exposure category versus non-exposure in both…

Effect of short exposure to radiofrequency electromagnetic fields on saliva biomarkers: a study on the electrohypersensitive individuals.

Research RF Safe Research Library Jan 1, 2019

This double-blind provocation study examined whether short RF-EMF exposure alters salivary biomarkers in electrohypersensitive (EHS) individuals. Ten participants underwent sham and real exposure sessions with consecutive GSM 900, GSM 1800, DECT, and Wi‑Fi signals for 5 minutes each. The study reports no significant…

Genotoxic and cytotoxic effects of 50 Hz 1 mT electromagnetic field on larval rainbow trout (Oncorhynchus mykiss), Baltic clam (Limecola balthica) and common ragworm (Hediste diversicolor).

Research RF Safe Research Library Jan 1, 2019

This animal study assessed genotoxic and cytotoxic responses in aquatic species exposed to a 50 Hz, 1 mT electromagnetic field. Nuclear abnormality assays indicated significant increases in multiple genotoxicity endpoints across species, with the most pronounced effects in Baltic clam gill cells. Cytotoxicity…

Non-Ionizing Radiation for Cardiac Human Amniotic Mesenchymal Stromal Cell Commitment: A Physical Strategy in Regenerative Medicine.

Research RF Safe Research Library Jan 1, 2018

This in vitro study exposed human amniotic mesenchymal stromal cells to an ELF-EMF stimulus (7 Hz, 2.5 µT) and compared responses with a nitric oxide chemical treatment. The authors report reduced cell proliferation with no change in metabolic activity, vitality, or apoptosis after ELF-EMF exposure. They also report…

Effect of acute exposure to radiofrequency electromagnetic fields emitted by a mobile phone (GSM 900 MHz) on electrodermal responsiveness in healthy human.

Research RF Safe Research Library Jan 1, 2018

This study examined whether acute GSM 900 MHz mobile phone exposure affects electrodermal activity responses to auditory stimuli in 28 young volunteers. The authors report no exposure-related changes in SCR latency, amplitude, integral, or number of responses. Session differences in skin conductance/tonic…

Eotaxin‑1 and MCP‑1 serve as circulating indicators in response to power frequency electromagnetic field exposure in mice.

Research RF Safe Research Library Jan 1, 2018

This animal study exposed young Balb/c mice to constant 50 Hz power-frequency EMF at 0.1, 0.5, or 2.5 mT for 90 days. Body weight did not differ between exposed and control groups, but serum chemokine profiles showed exposure-related changes. EOTAXIN-1 and MCP-1 were significantly increased at 0.5 mT, which the…

Effects of electromagnetic field, cisplatin and morphine on cytotoxicity and expression levels of DNA repair genes.

Research RF Safe Research Library Jan 1, 2018

This in vitro study examined how morphine, a 50-Hz 0.50 mT electromagnetic field (intermittent), and cisplatin co-treatments affected DNA repair gene expression and cytotoxicity in MCF-7 and SH-SY5Y cells. Morphine alone was reported to down-regulate examined DNA repair genes, whereas morphine plus EMF did not…

A Single Exposure to GSM-1800 MHz Signals in the Course of an Acute Neuroinflammatory Reaction can Alter Neuronal Responses and Microglial Morphology in the Rat Primary Auditory Cortex.

Research RF Safe Research Library Jan 1, 2018

This animal study examined whether acute GSM-1800 MHz exposure affects the auditory cortex during experimentally induced neuroinflammation. In LPS-treated rats, a single 2-hour head-only exposure (average SAR 1.55 W/kg in auditory cortex) was associated with altered microglial morphology and reduced neuronal activity…

Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.

Research RF Safe Research Library Jan 1, 2018

This study reports the identification of an electromagnetic perceptive gene (EPG) from glass catfish and its expression in mammalian cells, neuronal cultures, and rat brain. The authors report that magnetic/EMF stimulation remotely increased intracellular calcium in EPG-expressing cells and neurons. They also report…

Effect of 900-MHz Electromagnetic Field on the Cerebellum: A Histopathological Investigation.

Research RF Safe Research Library Jan 1, 2018

This animal study evaluated histopathological effects of 900-MHz RF-EMF exposure on the rat cerebellum. The exposed group showed intense caspase-3 expression in Purkinje and granular cells and histological changes consistent with apoptosis. Cerebellar layer thickness appeared reduced in exposed animals, although…

Low frequency electromagnetic field decreases ischemia-reperfusion injury of human cardiomyocytes and supports their metabolic function.

Research RF Safe Research Library Jan 1, 2018

This in vitro study tested whether extremely low frequency/low frequency electromagnetic field (LF-EMF) exposure modifies ischemia-reperfusion injury in human cardiac-related cell types. Using LDH and MMP-2 activities and fluorescein diacetate staining, the authors report that short courses of LF-EMF reduced cellular…

Electromagnetic field exposure (50 Hz) impairs response to noxious heat in American cockroach.

Research RF Safe Research Library Jan 1, 2018

This animal study examined whether 50 Hz electromagnetic field exposure (7 mT) affects heat-escape behavior and oxidative balance in American cockroaches. The authors report increased latency to escape from noxious heat after 24 h, 72 h, and 7 days of exposure. Biomarkers suggested oxidative stress, with elevated…

Does precautionary information about electromagnetic fields trigger nocebo responses? An experimental risk communication study.

Research RF Safe Research Library Jan 1, 2018

This experimental study tested whether providing precautionary information about EMF from WLAN devices increases symptom reporting during an alleged exposure situation. In a sham-exposure design (N=137), participants received either basic information about current WLAN exposure limits or additional precautionary…

SAR thresholds for electromagnetic exposure using functional thermal dose limits.

Research RF Safe Research Library Jan 1, 2018

This paper analyzes how conservative current localized RF EMF SAR basic restrictions may be by estimating the implied safety factor. The authors derive thermal dose–functional SAR limits from literature-reported thresholds for acute local tissue damage and compare these to existing basic restrictions. They report…

After-effect induced by microwave radiation in human electroencephalographic signal: a feasibility study.

Research RF Safe Research Library Jan 1, 2018

This feasibility study tested whether microwave radiation (450 MHz, 40 Hz modulation; 1 g peak spatial average SAR 0.3 W/kg) can induce detectable event-related potentials in EEG. In one subject across four sessions, EEG responses time-locked to exposure offset showed increased alpha-band signal and about a twofold…

Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats

Research RF Safe Research Library Mar 1, 2017

This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…

The beneficial effect of ginsenosides extracted by pulsed electric field against hydrogen peroxide-induced oxidative stress in HEK-293 cells.

Research RF Safe Research Library Jan 1, 2017

This in vitro study compared ginsenosides extracted using pulsed electric field (PEF) versus solvent cold soak extraction (SCSE). The abstract reports that PEF extracts had higher antioxidant capacity and provided greater protection against hydrogen peroxide-induced oxidative stress in HEK-293 cells, including…

The response of human bacteria to static magnetic field and radiofrequency electromagnetic field.

Research RF Safe Research Library Jan 1, 2017

This study investigated how laboratory bacterial strains and skin bacterial isolates respond to static magnetic fields and radiofrequency EMF described as cell phone-level exposure. The authors report variable and inconsistent growth responses across species and across isolates from four subjects. They propose that…

Effects of extremely low frequency electromagnetic fields on morphine analgesia and tolerance in rats.

Research RF Safe Research Library Jan 1, 2017

This animal study examined whether extremely low frequency electromagnetic field exposure alters morphine analgesia and tolerance in rats. Rats exposed to a 50 Hz magnetic field (reported as 5 mT) showed higher morphine analgesic effects than rats given morphine without field exposure. In morphine-tolerant rats,…

Different profiles of the mRNA levels of DNA repair genes in MCF-7 and SH-SY5Y cells after treatment with combination of cisplatin, 50-Hz electromagnetic field and bleomycin.

Research RF Safe Research Library Jan 1, 2017

This in vitro study examined whether a 50-Hz, 0.50 mT intermittent electromagnetic field modifies responses to cisplatin and bleomycin in MCF-7 and SH-SY5Y cells. The authors report increased susceptibility in MCF-7 cells with EMF added to cisplatin+bleomycin, while SH-SY5Y susceptibility was unchanged. They also…

Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.

Research RF Safe Research Library Jan 1, 2017

This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…

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