Enhancement of osteogenic differentiation of rat adipose tissue-derived mesenchymal stem cells by zinc sulphate under electromagnetic field via the PKA, ERK1/2 and Wnt/β-catenin signaling pathways.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study examined rat adipose-derived mesenchymal stem cells exposed to zinc sulphate in the presence of an ELF electromagnetic field (50 Hz, 20 mT). The authors report increased osteogenic differentiation markers (gene expression, ALP activity, and calcium levels) under combined ZnSO4+EMF conditions,…
The effects of human height and mass on the calculated induced electric fields at 50 Hz for comparison with the EMF Directive 2013/35/EU.
Research
RF Safe Research Library
Jan 1, 2017
This computational study examined how human height and mass influence calculated induced electric fields in the body from external 50 Hz electric and magnetic fields. Anatomically realistic human models derived from the MAXWEL phantom were varied across a range of heights and masses and used to simulate induced…
An innovative therapy for peri-implantitis based on radio frequency electric current: numerical simulation results and clinical evidence.
Research
RF Safe Research Library
Jan 1, 2016
This conference paper describes a peri-implantitis therapy using radio frequency electric current and presents numerical simulations alongside referenced clinical evidence. The abstract reports 81% successful treatment across 66 implants in 46 patients. FEM modeling suggests current preferentially concentrates in…
Variation of radio frequency induced power deposition due to second surrounding tissue.
Research
RF Safe Research Library
Jan 1, 2016
This engineering study investigated RF-induced power deposition from insulated leads of different lengths positioned near two surrounding tissues. The authors report that both the electromagnetic lead models and the resulting power deposition depended strongly on the electrical properties of both tissues. Using a…
Evaluation of the electric field in the brain during transcranial direct current stimulation: A sensitivity analysis.
Research
RF Safe Research Library
Jan 1, 2016
This computational study used finite element modeling to estimate the electric field distribution in the brain during tDCS for two electrode montages targeting the left DLPFC. It systematically varied isotropic tissue conductivity profiles to assess sensitivity of predicted E-field magnitude and components in the…
Microwave to near-infrared conversion with a millimeter-scale wireless laser for activating molecular transducers.
Research
RF Safe Research Library
Jan 1, 2016
This conference paper reports an engineering approach to convert wireless microwave power into near-infrared light using a miniaturized, wirelessly powered laser. The device is described as millimeter-scale and capable of being powered through >1 cm of tissue. The abstract focuses on enabling in vivo activation of…
Cardiac magnetic resonance radiofrequency tissue tagging for diagnosis of constrictive pericarditis: A proof of concept study.
Research
RF Safe Research Library
Jan 1, 2016
This proof-of-concept cohort study evaluated cardiac magnetic resonance (CMR) radiofrequency tissue tagging to diagnose constrictive pericarditis and compared results with surgical findings and cardiac catheterization. In 16 patients who underwent pericardiectomy, CMR positivity agreed 100% with intraoperative…
Near-field radiofrequency electromagnetic exposure assessment
Research
RF Safe Research Library
Jan 1, 2015
This paper presents a near-field RF exposure assessment method comparing standard SAR estimation from E-field measurements in tissue-simulating liquid with a proposed approach based on incident H-field measurements. Experiments were conducted at 900, 1800, and 2450 MHz using dipole antennas and a flat phantom, with…
Impacts of exposure to 900 MHz mobile phone radiation on liver function in rats.
Research
RF Safe Research Library
Jan 1, 2015
This animal experiment randomized 20 male Sprague-Dawley rats to 900 MHz electromagnetic radiation exposure (4 h/day for 18 days) or no exposure. The exposed group showed increased oxidative stress markers in liver tissue (higher MDA, lower GSH) and reported histopathological changes, along with increased apoptosis…
Effects of extremely low-frequency electric fields at different intensities and exposure durations on mismatch negativity
Research
RF Safe Research Library
Jul 11, 2014
This rat study examined whether 50-Hz extremely low-frequency electric fields at 12 or 18 kV/m for 2 or 4 weeks affect mismatch negativity (MMN) and markers of oxidative damage/apoptosis in brain tissue. MMN amplitude was reported to be significantly reduced only in the 18 kV/m, 4-week exposure group versus the…
Long-term efficacy of radiofrequency treatment of turbinate hypertrophy: a patient based point of view.
Research
RF Safe Research Library
Jan 1, 2013
This observational study followed 36 patients for 2 years after temperature-controlled radiofrequency tissue volume reduction for turbinate hypertrophy. Patients reported significantly lower VAS symptom scores (nasal obstruction, headache, rhinorrhoea, anosmia) after treatment compared with baseline. Urban residence…
Microwave radiation induced oxidative stress, cognitive impairment and inflammation in brain of Fischer rats.
Research
RF Safe Research Library
Jan 1, 2012
This animal study exposed male Fischer-344 rats to 900 MHz or 1800 MHz microwave radiation for 30 days (2 h/day) and compared outcomes to sham exposure. The authors report significant cognitive impairment along with increased oxidative stress in brain tissue in exposed rats. They also report increased inflammatory…
Down-regulation of metallothionein 1 and 2 after exposure to electromagnetic field in mouse testis.
Research
RF Safe Research Library
Jan 1, 2011
This animal study examined mouse testis after 8 weeks of exposure to a 3 MT electromagnetic field (4 hours/day). The authors report significant histological changes (increased primary spermatocytes, increased Leydig cells, and increased basement membrane thickness) in exposed mice versus controls. MT1 and MT2…
Electric field analysis of breast tumor cells.
Research
RF Safe Research Library
Jan 1, 2011
This paper reports a MAXWELL 3D simulation study of electric field distribution in a tissue/tumor model relevant to electrical-pulse-mediated drug delivery. The authors report lower electric field strength in tumor tissue compared with normal cells. They interpret this as potentially increasing tumor susceptibility…
Selenium supplementation ameliorates static magnetic field-induced disorders in antioxidant status in rat tissues.
Research
RF Safe Research Library
Jan 1, 2011
This rat study examined whether selenium supplementation modifies antioxidant-related changes associated with sub-acute static magnetic field exposure. The authors report that SMF exposure altered tissue selenium levels and antioxidant enzyme activities in a tissue-specific manner, including decreased selenium and…
Impact of a pulsed electric field on damage of plant tissues: effects of cell size and tissue electrical conductivity.
Research
RF Safe Research Library
Jan 1, 2011
This experimental and modeling study examined pulsed electric field (PEF) permeabilization in several fruit and vegetable tissues at 293 K using 1000 μs pulses and field strengths of 400 and 1000 V·cm(-1). While electroporation theory predicts greater damage in tissues with larger cells, the authors report this…
Ohmic heating of peaches in the wide range of frequencies (50 Hz to 1 MHz).
Research
RF Safe Research Library
Jan 1, 2010
This engineering/food science study examined ohmic heating of peaches at 60 V/cm using bipolar pulses across frequencies from 50 Hz to 1 MHz. Heating time to a target temperature and multiple electrical properties were frequency-dependent, particularly for intact tissue. The authors report faster electro-thermal…
Disintegration efficiency of pulsed electric field induced effects on onion (Allium cepa L.) tissues as a function of pulse protocol and determination of cell integrity by ¹H-NMR relaxometry.
Research
RF Safe Research Library
Jan 1, 2010
This experimental study examined how pulsed electric field (PEF) processing parameters affect cell membrane rupture in onion tissue disks, using ion leakage as the primary integrity measure. Disintegration efficiency increased with field strength up to 500 V/cm and varied with pulse width, pulse number, and…
Critical electric field strengths of onion tissues treated by pulsed electric fields.
Research
RF Safe Research Library
Jan 1, 2010
This experimental study examined how pulsed electric fields affect onion tissue integrity and texture across different field strengths and pulse counts. It reports distinct critical field strengths for plasma membrane versus tonoplast membrane breakdown, with higher thresholds needed for tonoplast disruption. Effects…
The use of a standard radiofrequency energy delivery system to facilitate transseptal puncture.
Research
RF Safe Research Library
Jan 1, 2009
This paper describes a procedural technique for transseptal puncture that uses brief pulses of radiofrequency energy delivered from a standard electrosurgical cautery generator through the needle tip. The approach is presented as a way to facilitate septal traversal when tissue is elastic, aneurysmal, or thickened,…
Cutaneous remodeling and photorejuvenation using radiofrequency devices.
Research
RF Safe Research Library
Jan 1, 2009
This concise review discusses radiofrequency (RF) dermatologic devices used for nonablative skin rejuvenation and related indications. It characterizes RF effects on tissue as primarily thermal, aiming to heat targeted skin layers to trigger collagen changes and subsequent remodeling. The abstract cites preliminary…
Static magnetic field therapy: a critical review of treatment parameters.
Research
RF Safe Research Library
Jan 1, 2009
This critical review summarizes human research on static magnetic field (SMF) therapy delivered by permanent magnets attached to the skin and evaluates how well studies report SMF dosage and treatment parameters. Across 56 included studies, many did not report essential SMF characteristics (e.g., magnet dimensions,…
The effect of postoperative immobilization on the healing of radiofrequency heat probe modified tissue: assessment of tissue length, stiffness, and morphology.
Research
RF Safe Research Library
Jan 1, 2008
This animal study examined how postoperative immobilization affects healing after radiofrequency heat probe shrinkage in rabbit patellar tendons. Tendon length increased across all groups by 8 weeks, but 4 weeks of immobilization resulted in less elongation than free activity. Immobilized groups had reduced…
The effect of MRET polymer compound on SAR values of RF phones.
Research
RF Safe Research Library
Jan 1, 2008
This article describes a hypothesis and experimental testing of an MRET polymer compound applied to RF phones. It reports increased dielectric permittivity in water-based solutions and reduced SAR values in a tissue-simulating phantom head. It also reports no significant change in air measurements of phone signals,…
Greyscale intravascular ultrasound and IVUS-radiofrequency tissue characterisation to improve understanding of the mechanisms of coronary stent thrombosis in drug-eluting stents.
Research
RF Safe Research Library
Jan 1, 2008
This review describes proposed mechanical causes of drug-eluting stent thrombosis and notes that many are identifiable by greyscale intravascular ultrasound (IVUS). It highlights that evidence linking specific IVUS findings to stent thrombosis remains uncertain because relatively few stent thrombosis cases have been…