Selenium supplementation ameliorates static magnetic field-induced disorders in antioxidant status in rat tissues.
This rat study examined whether selenium supplementation modifies antioxidant-related changes associated with sub-acute static magnetic field exposure. The authors report that SMF exposure altered tissue selenium levels and antioxidant enzyme activities in a tissue-specific manner, including decreased selenium and GPx in some tissues and increased GSH and SOD in liver. Selenium supplementation reportedly restored some SMF-associated changes (notably selenium levels and GPx in kidney and muscle) but not elevated liver GSH and SOD.
Key points
- Male adult rats were exposed to a 128 mT static magnetic field for 1 hour per day over 5 days, with or without selenium supplementation.
- SMF exposure was reported to decrease selenium levels in kidney, muscle, and brain.
- SMF exposure was reported to decrease GPx activity in kidney and muscle, while GR activity was unchanged.
- In liver, SMF exposure was reported to increase total GSH levels and total SOD activity.
- Selenium supplementation in SMF-exposed rats restored selenium levels in kidney, muscle, and brain.
- Selenium supplementation raised GPx activity in kidney and muscle to control levels but did not normalize elevated liver GSH and SOD activity.
- The authors interpret the findings as SMF-induced alteration of antioxidant responses that can be partly ameliorated by selenium supplementation.
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AI-generated summaries may be incomplete or incorrect. This content is for informational purposes only and is not medical advice.
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