The CB1R of mPFC is involved in anxiety-like behavior induced by 0.8/2.65 GHz dual-frequency electromagnetic radiation
Research
RF Safe Research Library
Jan 1, 2025
This animal study reports that dual-frequency RF EMR exposure (0.8/2.65 GHz, 4 W/kg) induced anxiety-like behavior in mice. It also reports reduced CB1R and endocannabinoid levels in the mPFC and altered endocannabinoid system markers in the BLA. CB1R overexpression or knockdown in the mPFC reportedly decreased or…
Magneto-oncology: a radical pair primer
Research
RF Safe Research Library
Jan 1, 2025
This mini-review discusses the radical pair mechanism as a plausible biophysical route by which external magnetic fields could influence biochemical processes in living systems. It is intended as a primer for magneto-oncology researchers to assess whether observed magnetic-field-related biomedical effects may be…
Effects of electromagnetic field emitted by a 90 kHz WPT system on the cognitive functions and neuronal excitation of mice.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined whether EMF from a 90 kHz magnetic-coupling resonant wireless power transfer (WPT) system affects mouse cognition and hippocampal neuronal excitability. Mice were exposed for 2, 4, or 8 weeks and assessed with a Novel Object Recognition test and dentate gyrus patch-clamp recordings. The…
Assessing cell viability and genotoxicity in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz electromagnetic field radiations.
Research
RF Safe Research Library
Jan 1, 2025
This experimental study assessed cytotoxic and genotoxic endpoints in Trigonella foenum-graecum L. exposed to 2100 MHz and 2300 MHz EMF-r for 0.5–8 h/day. The authors report reduced root/shoot growth at longer daily exposures, increased chromosomal aberrations compared with controls, and reduced cell viability.…
Microglial Response to Inflammatory Stimuli Under Electromagnetic Field Exposure.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined whether extremely low frequency EMF exposure alters responses of TNF-α-stimulated human microglial cells (HMC3). Cells exposed to 2.5 or 5 Hz EMF for 3 minutes showed increased survival under high TNF-α conditions and reduced migration compared with TNF-α treatment alone. EMF also…
Electromagnetic Field Influence on the Bioavailability and Accumulation of Ketoprofen.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro/ex vivo study tested whether different magnetic-field configurations alter ketoprofen properties and its transdermal delivery in porcine skin using Franz diffusion cells. The authors report no change in ketoprofen molecular structure, but subtle changes in crystal structure and physicochemical…
Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined extremely low-frequency electromagnetic field (ELF-EMF) effects on spinal cord-derived neural stem cells (NSCs) from adult mice. The authors report that ELF-EMFs increase NSC proliferation and self-renewal with upregulation of Sox2. They also report activation of T-type calcium channels,…
Modulation of inflammatory response by electromagnetic field in Neuronal and Microglial cells.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro study examined whether low-frequency electromagnetic field (EMF) stimulation modulates inflammatory signaling in neuronal and microglial cell lines after induction of a pro-inflammatory state with TNF-α. The authors report reduced transcriptional expression of inflammatory target genes at 24 and 48…
Melatonin and omega-3 neuroprotection in prenatal rat spinal cord exposed to 900 MHz electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined prenatal 900 MHz EMF exposure (2 hours/day for 21 days) in pregnant rats and assessed spinal cord outcomes in male offspring at postnatal day 35. Volume-based stereological measures (GM/WM ratios and total spinal cord volume) did not differ significantly between groups. Microscopy reported…
Possible effects of melatonin and omega-3 on the obesity-related hypothalamic nuclei of the electromagnetic field-exposed offspring rats: a stereological and immunohistochemical analysis.
Research
RF Safe Research Library
Jan 1, 2025
This animal study examined whether prenatal exposure to a 900 MHz electromagnetic field affects obesity-related hypothalamic nuclei in male rat offspring and whether melatonin or omega-3 modifies these effects. The EMF-exposed group showed fewer neurons in the arcuate nucleus, stronger NPY immunoreactivity, and…
Sinusoidal Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Promotes Angiogenesis In Vitro.
Research
RF Safe Research Library
Jan 1, 2025
This in vitro/in ovo study examined whether extremely low-frequency electromagnetic stimulation (ELF-EMS; 13.5 mT at 10 and 60 Hz) activates angiogenic processes under homeostatic conditions. In human microvascular endothelial cells, ELF-EMS increased proliferation, migration/transmigration, and tube formation, with…
Growth and defense mechanism of Phaeocystis globosa exposed to extremely low frequency electromagnetic fields.
Research
RF Safe Research Library
Jan 1, 2025
This laboratory study exposed cultured Phaeocystis globosa to extremely low-frequency electromagnetic fields (ELF-EMF) at 0, 0.2, and 1 mT for 24 hours. The authors report increased cell density, photosynthesis, and chlorophyll a under ELF-EMF, alongside decreased protein and carbohydrate accumulation. Metabolomic…
Impact of Electromagnetic Fields on Gypsum and Silica Scaling in Reverse Osmosis.
Research
RF Safe Research Library
Jan 1, 2025
This engineering study evaluates electromagnetic field (EMF) treatment as a nonchemical method to control gypsum and silica scaling in reverse osmosis using synthetic brackish water and real RO concentrate. It reports EMF altered gypsum crystal morphology to form a more porous scale that was easier to remove with…
Impact of various electromagnetic fields on the transdermal permeability of naproxen and the effect of active compound exposure on magnetic field properties.
Research
RF Safe Research Library
Jan 1, 2025
This ex vivo study tested whether different magnetic-field modalities change transdermal delivery of naproxen through pigskin. Rotating magnetic fields (RMF) at 50 Hz produced the greatest increase in permeation metrics versus a no-EMF control, while negatively polarized static fields reduced permeation.…
The Impact of Mobile Phone Electromagnetic Waves on the Neurons and Blood Brain Barrier Integrity in the Chick Embryo
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed chick embryos to electromagnetic waves from a mobile phone and compared them with unexposed controls. Electron microscopy on days 10 and 15 reported neuronal and cerebellar cellular alterations in the exposed group, including features described as apoptosis and mitochondrial swelling. The…
Role of radio-frequency electromagnetic waves in causing oxidative stress
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed fertilized chick eggs to a nearby 1800 MHz mobile phone that was called repeatedly (50 minutes/day) and assessed embryos at days 10 and 15. The exposed group reportedly showed mitochondrial abnormalities in liver, brain, and heart tissues on electron microscopy, along with increased HSP70 in…
The use of different exposure metrics in the research about the health impacts of electromagnetic fields
Research
RF Safe Research Library
Jan 1, 2024
This policy brief focuses on how RF-EMF exposure should be quantified in health research, emphasizing the role of near-field sources and proposing cumulative dose (J/kg/day) as a health-relevant metric. It reports mean cumulative dose estimates of 0.29 J/kg/day for the whole body and 0.81 J/kg/day for the brain. The…
Temporal Change of Outdoor Rf-Emf Levels Four in European Countries: A Microenvironmental Measurement Study
Research
RF Safe Research Library
Jan 1, 2024
This microenvironmental measurement study assessed temporal trends in outdoor RF-EMF exposure from 2016 to 2023 in four European countries using repeated walking-route measurements with exposimeters. The abstract reports that data did not suggest significant changes in mobile base station (downlink) exposure over…
Experimental Study of Stress Reactions Induced by Low-Intensity Microwave Radiation
Research
RF Safe Research Library
Jan 1, 2024
This animal experiment examined hematopoietic and immune-related indicators in mice after repeated exposure to low-intensity microwave radiation. Exposure involved monochromatic pulsed fields in the 2.27–2.78 GHz range with average power flux density of 60 μW/cm² and doses of 0.086–0.86 J/g. The authors report…
Effects of radiofrequency field from 5G communication on fecal microbiome and metabolome profiles in mice
Research
RF Safe Research Library
Jan 1, 2024
This animal study exposed adult male C57BL/6 mice to a 4.9 GHz radiofrequency field for three weeks (1 hour/day) and compared them with a sham group. The abstract reports altered fecal microbiome composition with reduced diversity in the RF group, along with 258 significantly differentially abundant fecal…
External low energy electromagnetic fields affect heart dynamics: surrogate for system synchronization, chaos control and cancer patient's health.
Research
RF Safe Research Library
Jan 1, 2024
This paper discusses how low-energy, specifically modulated electromagnetic fields delivered via an active closed-loop medical device may temporarily alter plasma membrane ionic flow and heart oscillation dynamics. It frames heart rate dynamics as a surrogate for systemic synchronization/entrainment and suggests…
Impact of Extremely Low-Frequency Electromagnetic Fields on Skeletal Muscle of Sedentary Adult Mice: A Pilot Study.
Research
RF Safe Research Library
Jan 1, 2024
This pilot animal study examined ELF-EMF exposure (0.1 or 1.0 mT, 1 h/day up to 5 weeks) in sedentary adult male C57BL/6 mice, with or without N-acetyl-cysteine (NAC) supplementation. The authors report a transient increase in muscle strength after 2 weeks at 1.0 mT, accompanied by higher PAX7 and myosin heavy chain…
Evaluation of electric field (E) exposure levels and its relationship with the sleep quality of residents around the BTS antennas in Sabzevar, Iran.
Research
RF Safe Research Library
Jan 1, 2024
This study measured RF electric field exposure around BTS antennas in Sabzevar, Iran across multiple times and distances, and assessed residents' sleep quality. E-field levels varied by time, distance, and suburban versus downtown location, while microenvironment differences were not significant. Sleep quality…
Exposure to Radiofrequency Induces Synaptic Dysfunction in Cortical Neurons Causing Learning and Memory Alteration in Early Postnatal Mice.
Research
RF Safe Research Library
Jan 1, 2024
This animal study examined 1850 MHz RF-EMF exposure (SAR 4.0 W/kg) in early postnatal mice and assessed synaptic and behavioral outcomes. The abstract reports reductions in dendritic spine maturation markers, decreases in PSD-95 puncta, inhibited neurite outgrowth, and downregulation of synapse-related genes in…
Thermodynamic Considerations on the Biophysical Interaction between Low-Energy Electromagnetic Fields and Biosystems.
Research
RF Safe Research Library
Jan 1, 2024
This paper presents a thermodynamic model intended to explain how extremely low-frequency electromagnetic fields (ELF-EMFs) may interact with cells. The authors propose that ELF-EMFs directly interfere with the cellular membrane, producing biological responses linked to energy conversion and changes in flows across…