Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed keratinocytes from atopic dermatitis patients and healthy controls, plus two keratinocyte cell lines, to a 900 MHz electromagnetic field for 60 minutes. AD-derived keratinocytes showed higher Fas/FasL signaling markers and increased secretion of multiple cytokines versus controls. EMF…
Impact of Long-Term RF-EMF on Oxidative Stress and Neuroinflammation in Aging Brains of C57BL/6 Mice.
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Jan 1, 2018
This animal study exposed 14-month-old C57BL/6 mice to 1950 MHz RF-EMF (SAR 5 W/kg) for 8 months. The authors report that aging was associated with increased oxidative damage, DNA damage, apoptosis, and glial activation markers in brain tissue. Long-term RF-EMF exposure did not change these markers in aged mice and…
Effect of acute exposure to radiofrequency electromagnetic fields emitted by a mobile phone (GSM 900 MHz) on electrodermal responsiveness in healthy human.
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Jan 1, 2018
This study examined whether acute GSM 900 MHz mobile phone exposure affects electrodermal activity responses to auditory stimuli in 28 young volunteers. The authors report no exposure-related changes in SCR latency, amplitude, integral, or number of responses. Session differences in skin conductance/tonic…
Effects of 900-MHz electromagnetic fields exposure throughout middle/late adolescence on the kidney morphology and biochemistry of the female rat.
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Jan 1, 2018
This animal study examined kidney effects in female rats exposed to continuous 900 MHz EMF for 1 hour daily during postnatal days 35–59. The authors report multiple histopathological alterations in kidneys of the EMF-exposed group, while control and sham groups showed no pathology. TOS and OSI were reported to be…
A Single Exposure to GSM-1800 MHz Signals in the Course of an Acute Neuroinflammatory Reaction can Alter Neuronal Responses and Microglial Morphology in the Rat Primary Auditory Cortex.
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Jan 1, 2018
This animal study examined whether acute GSM-1800 MHz exposure affects the auditory cortex during experimentally induced neuroinflammation. In LPS-treated rats, a single 2-hour head-only exposure (average SAR 1.55 W/kg in auditory cortex) was associated with altered microglial morphology and reduced neuronal activity…
Effect of 900-MHz Electromagnetic Field on the Cerebellum: A Histopathological Investigation.
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Jan 1, 2018
This animal study evaluated histopathological effects of 900-MHz RF-EMF exposure on the rat cerebellum. The exposed group showed intense caspase-3 expression in Purkinje and granular cells and histological changes consistent with apoptosis. Cerebellar layer thickness appeared reduced in exposed animals, although…
Spatial electromagnetic field intensity modelling of global system for mobile communication base stations in the Istanbul Technical University Ayazaga campus area.
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Jan 1, 2018
This study measured RF electric field intensities at 900 and 1800 MHz at 29 points on the Istanbul Technical University campus and produced spatial EMF intensity heat maps using GIS interpolation. Three interpolation methods were compared and the mapped measurements were evaluated against ICNIRP reference limits. All…
Does acute radio-frequency electromagnetic field exposure affect visual event-related potentials in healthy adults?
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Jan 1, 2018
This double-blind, randomized, counterbalanced study tested whether acute GSM-like 920 MHz RF-EMF exposure affects visual event-related potentials in 36 healthy adults. Compared with sham, exposure was associated with reduced P1 amplitude and increased anterior N1 latency, with no effects on other ERP measures. The…
Gene Expression Analysis in Human Peripheral Blood Cells after 900 MHz RF-EMF Short-Term Exposure.
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Jan 1, 2018
This ex vivo/in vitro study exposed peripheral blood cells from five human donors to a 900 MHz continuous-wave RF-EMF for up to 90 minutes (average SAR 9.3 W/kg). After false discovery rate adjustment, the authors report no EMF-specific gene expression changes on microarray analysis. Although low-stringency analysis…
Effect of a 1800 MHz electromagnetic field emitted during embryogenesis on chick development and hatchability.
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Jan 1, 2018
This animal study examined 1800 MHz EMF exposure during chick embryogenesis and assessed development, malformations, organ measures, and stress-related biomarkers. The authors report earlier pipping and hatching without an increase in malformations or changes in chick quantity/quality. They also report decreased…
Effects of 1800 MHz RF-EMF exposure on DNA damage and cellular functions in primary cultured neurogenic cells.
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Jan 1, 2018
This in vitro study exposed primary cultured astrocytes, microglia, and cortical neurons to 1800 MHz RF-EMF at 4.0 W/kg SAR to assess DNA damage and cellular functions. The authors report no significant induction of γH2AX foci and no significant changes in cytokine secretion or dendrite/synapse morphological…
Continuous 900-megahertz electromagnetic field applied in middle and late-adolescence causes qualitative and quantitative changes in the ovarian morphology, tissue and blood biochemistry of the rat.
Research
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Jan 1, 2018
This animal study exposed adolescent female rats to a 900-MHz electromagnetic field for 1 hour per day from postnatal days 35 to 59 and assessed ovarian histology and biochemical markers. The EMF group showed multiple histopathological changes in ovarian tissue and had fewer secondary follicles than the other groups.…
Effects of 1950 MHz radiofrequency electromagnetic fields on Aβ processing in human neuroblastoma and mouse hippocampal neuronal cells.
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Jan 1, 2018
This in vitro study exposed HT22 mouse hippocampal neuronal cells and SH-SY5Y human neuroblastoma cells to 1950 MHz RF-EMF at SAR 6 W/kg for 2 hours per day over 3 days. RF-EMF exposure reduced mRNA levels of several Aβ-processing genes in HT22 cells, but did not change APP mRNA in SH-SY5Y cells. Protein levels of…
After-effect induced by microwave radiation in human electroencephalographic signal: a feasibility study.
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Jan 1, 2018
This feasibility study tested whether microwave radiation (450 MHz, 40 Hz modulation; 1 g peak spatial average SAR 0.3 W/kg) can induce detectable event-related potentials in EEG. In one subject across four sessions, EEG responses time-locked to exposure offset showed increased alpha-band signal and about a twofold…
Oxidative and mutagenic effects of low intensity GSM 1800 MHz microwave radiation
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Jan 1, 2018
This animal study used developing quail embryos to assess oxidative and mutagenic effects of low-intensity GSM 1800 MHz radiation from a commercial smartphone. The authors report statistically significant increases in oxidative stress markers, DNA integrity damage, and oxidative DNA damage (8-oxo-dG) in exposed…
NTP Technical Report on the Toxicology and Carcinogenesis Studies: GSM- and CDMA-modulated Cell Phone RFR, NTP TR 595
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Jan 1, 2018
This NTP technical report describes long-term rat studies exposing animals to 900 MHz GSM and CDMA-modulated radiofrequency radiation at whole-body SAR levels of 0, 1.5, 3, and 6 W/kg, including exposure beginning before birth. The abstract reports NTP concluded there was "clear evidence" for malignant schwannoma of…
Effect of Exposure to 900 MHz GSM Mobile Phone Radiofrequency Radiation on Estrogen Receptor Methylation Status in Colon Cells of Male Sprague Dawley Rats
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RF Safe Research Library
Mar 1, 2017
This animal study exposed male Sprague-Dawley rats to 900 MHz GSM mobile phone RF radiation for 4 hours and assessed ERα promoter methylation in colon tissue. The authors report altered ERα methylation patterns versus controls after RF exposure. They also report no radioadaptive response in ERα methylation following…
Effect of long-term exposure of mice to 900 MHz GSM radiation on experimental cutaneous candidiasis.
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Jan 1, 2017
This animal study examined whether long-term 900 MHz GSM-like microwave exposure affects experimentally induced cutaneous candidiasis in BALB/c mice. Exposed mice reportedly had delayed wound healing and higher Candida loads in skin lesions compared with unexposed mice. Following systemic Candida challenge, exposed…
RF-EMF exposure at 1800 MHz did not elicit DNA damage or abnormal cellular behaviors in different neurogenic cells.
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Jan 1, 2017
This in vitro study assessed whether intermittent 1800 MHz RF-EMF exposure induces DNA damage or alters cellular behavior in three neurogenic cell lines. Cells were exposed at an average SAR of 4.0 W/kg for 1, 6, or 24 hours and evaluated for γH2AX foci, cell cycle progression, proliferation, and viability. The…
No adverse effects detected for simultaneous whole-body exposure to multiple-frequency radiofrequency electromagnetic fields for rats in the intrauterine and pre- and post-weaning periods.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed pregnant Sprague-Dawley rats and their offspring to simultaneous whole-body multifrequency RF signals spanning 800 MHz to 5.2 GHz. Exposure occurred 20 hours per day from gestational day 7 to weaning, with F1 offspring exposed up to 6 weeks of age. Across multiple endpoints including growth,…
Lasting hepatotoxic effects of prenatal mobile phone exposure.
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Jan 1, 2017
This animal study examined liver outcomes in rat offspring 60 days after prenatal exposure to a 900 MHz electromagnetic field for 24 hours/day during gestation. The exposed group showed biochemical changes consistent with oxidative stress (higher MDA, lower GSH) and elevated liver enzymes (ALT, AST). Histopathology…
Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields.
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Jan 1, 2017
This rat study examined 900 MHz EMF exposure for 60 minutes per day over 15 days and assessed hippocampal and cerebellar outcomes, behavior, and serum enzyme activity. The EMF-only group showed significant neuronal cell losses in multiple brain regions and worse passive avoidance performance compared with other…
Exposure to 2100 MHz electromagnetic field radiations induces reactive oxygen species generation in roots.
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Jan 1, 2017
This experimental study examined whether 2100 MHz cell phone-related RF-EMF exposure affects oxidative stress markers in onion roots. After 1–4 hours of continuous-wave exposure in a single day, the study reports increased lipid peroxidation and ROS-related measures (MDA, hydrogen peroxide, superoxide anion).…
Does omega-3 have a protective effect on the rat adrenal gland exposed to 900 MHz electromagnetic fields?
Research
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Jan 1, 2017
This animal study examined whether omega-3 modifies adrenal gland changes in rats exposed to 900 MHz electromagnetic fields. Rats exposed 60 minutes/day for 15 days showed significantly increased adrenal gland volume versus controls. Omega-3 co-treatment was associated with significantly lower adrenal gland volume…
Antenna Design and SAR Analysis on Human Head Phantom Simulation for Future Clinical Applications.
Research
RF Safe Research Library
Jan 1, 2017
This study developed a mathematical and computer simulation model to analyze RF-EMF exposure in a human head phantom, motivated by potential therapeutic applications. The modeled exposure used a Yagi-Uda antenna at 64 MHz with SAR 0.6 W/kg and compared field distribution using one versus four antennas. COMSOL Bioheat…