Effects of repeated exposure to 50 Hz electromagnetic field on breast cancer cells.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study exposed two human breast cancer cell lines to a 50 Hz ELF-EMF (20 mT) for 3 hours/day for up to four days. The authors report reduced viability and apoptosis-related findings in MDA-MB-231 cells, with no significant viability change in MCF-7 cells. Cell-cycle effects differed by cell line,…
What evidence exists of crop plants response to exposure to static magnetic and electromagnetic fields? A systematic map protocol.
Research
RF Safe Research Library
Jan 1, 2022
This paper describes a protocol for a systematic map of evidence on how food crops and model plants respond to exposure to static magnetic fields and non-ionizing electromagnetic fields. The authors cite reports of potential agronomic benefits but also inconsistent protocols and contradictory outcomes, and they…
Static and Electromagnetic Fields Differently Affect Proliferation and Cell Death Through Acid Enhancement of ROS Generation in Mesenchymal Stem Cells.
Research
RF Safe Research Library
Jan 1, 2022
This in vitro study examined how a 20 mT static magnetic field and a 20 mT 50 Hz electromagnetic field affect mesenchymal stem cells under conditions involving ROS and acidic pH. The authors report increased ROS and antioxidant-response markers (Nrf2, SOD2, GST) across SMF, EMF, and combined exposures, with…
Bidirectional Effect of Repeated Exposure to Extremely Low-Frequency Electromagnetic Field (50 Hz) of 1 and 7 mT on Oxidative/Antioxidative Status in Rat's Brain: The Prediction for the Vulnerability to Diseases.
Research
RF Safe Research Library
Jan 1, 2022
This rat study examined repeated 50 Hz ELF-EMF exposure (1 or 7 mT) and measured oxidative stress and antioxidant defense markers in the prefrontal cortex, including responses to a subsequent open-field stressor. The authors report intensity- and repetition-dependent effects: 1 mT produced weak changes and was…
Necroptosis triggered by ROS accumulation and Ca overload, partly explains the inflammatory responses and anti-cancer effects associated with 1Hz, 100 mT ELF-MF in vivo.
Research
RF Safe Research Library
Jan 1, 2021
This animal and in vitro study examined ELF magnetic field exposure in a mouse breast tumor model and a breast cancer cell line. The authors report tumor growth suppression and reduced expression of Ki-67, CD31, VEGFR2, and MMP-9 after exposure. They also report increased IFN-γ and TNF-α and increased…
Low-frequency electromagnetic field influences human oral mucosa keratinocyte viability in response to lipopolysaccharide or minocycline treatment in cell culture conditions.
Research
RF Safe Research Library
Jan 1, 2021
This in vitro study examined whether low-frequency electromagnetic field (LF-EMF) exposure affects viability of human oral mucosa keratinocytes. Apoptosis (early/late) and necrosis were measured by flow cytometry, including conditions with lipopolysaccharide (LPS) or minocycline. The authors report that LF-EMF, alone…
Effect of Exposure to a Radiofrequency Electromagnetic Field on Body Temperature in Anesthetized and Non-Anesthetized Rats.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined whether anesthesia and body mass modify body temperature responses to 915 MHz RF exposure at 4 W/kg whole-body SAR for 8 hours. Non-anesthetized, free-moving rats showed no significant temperature change during exposure. In contrast, anesthetized rats showed marked temperature increases,…
Combined Effects of Radiofrequency Electromagnetic Fields and X-Ray in Renal Tissue and Function.
Research
RF Safe Research Library
Jan 1, 2020
This animal experiment randomized 96 male Wistar rats to RF-EMF exposures (900/1800 MHz mobile phone or 2.4 GHz Wi-Fi), 8 Gy x-ray, or combinations, and assessed kidney function markers and histopathology. Creatinine was reported significantly higher and the BUN/Cr ratio significantly lower in the Wi-Fi group versus…
Short ELF-EMF Exposure Targets SIRT1/Nrf2/HO-1 Signaling in THP-1 Cells.
Research
RF Safe Research Library
Jan 1, 2020
This in vitro study examined 50 Hz, 1 mT ELF-EMF exposure in LPS-treated THP-1 cells for 1–24 hours. The authors report increased HO-1 expression and Nrf2-related signaling, with nuclear enrichment of HO-1 and modulation of SIRT1/NF-κB pathways. They interpret these molecular changes as suggesting a protective,…
Assessment of function, histopathological changes, and oxidative stress in liver tissue due to ionizing and non-ionizing radiations.
Research
RF Safe Research Library
Jan 1, 2020
This animal study evaluated liver function, histopathology, and oxidative stress markers after exposure to RF-EMF (900/1800 MHz and 2.4 GHz), x-rays (10 cGy or 8 Gy), and combinations including RF-EMF pre-exposure. Some liver enzymes (AST, ALT, ALP) showed some association with irradiation, while…
Effect of Extremely Low Power Time-Varying Electromagnetic Field on Germination and Other Characteristics in Foxtail Millet (Setaria italica) Seeds.
Research
RF Safe Research Library
Jan 1, 2020
This study evaluated extremely low, time-varying EMF “magneto-priming” to optimize germination in foxtail millet seeds using a central composite design and response surface methodology. The authors report optimal germination at 10 Hz, 30,007 nT, and 30 minutes, with improvements in germination percentage and multiple…
Infected Ixodes ricinus ticks are attracted by electromagnetic radiation of 900 MHz.
Research
RF Safe Research Library
Jan 1, 2020
This animal study tested whether Ixodes ricinus ticks show behavioral responses to 900 MHz radio-frequency electromagnetic fields in a radiation-shielded tube. Ticks were attracted to the irradiated area, and the attraction was reported as stronger among ticks infected with Rickettsia spp. The authors raise the…
Anthropogenic electromagnetic fields (EMF) influence the behaviour of bottom-dwelling marine species.
Research
RF Safe Research Library
Jan 1, 2020
This animal study examined behavioural responses of American lobster and Little skate to EMF emissions from a subsea HVDC transmission cable. It reports a marked increase in exploratory/foraging behaviour in skates and a subtler exploratory response in lobsters when exposed to cable EMF. The authors also measured…
Immune response of mollusk Onchidium struma to extremely low-frequency electromagnetic fields (ELF-EMF, 50 Hz) exposure based on immune-related enzyme activity and De novo transcriptome analysis.
Research
RF Safe Research Library
Jan 1, 2020
This animal study exposed the mollusk Onchidium struma to 50 Hz ELF-EMF at 100 μT or 500 μT for up to one week and assessed immune-related cell counts, enzyme activities, and transcriptomic changes. The 100 μT group showed increased total coelomocyte and spherulocyte density versus control and 500 μT, while some cell…
Lipidomic alteration and stress-defense mechanism of soil nematode Caenorhabditis elegans in response to extremely low-frequency electromagnetic field exposure.
Research
RF Safe Research Library
Jan 1, 2019
This animal (nematode) study exposed Caenorhabditis elegans to 50 Hz, 3 mT extremely low-frequency EMF and assessed multi-omics responses. The authors report significant lipidomic, proteomic, and transcriptomic alterations, including increased triacylglycerols. Pathway analyses suggest disrupted lipid metabolism,…
T-Cell Differentiation to T Helper 9 Phenotype is Elevated by Extremely Low-Frequency Electromagnetic Fields Via Induction of IL-2 Signaling.
Research
RF Safe Research Library
Jan 1, 2019
This in vitro study examined 60 Hz extremely low-frequency EMF exposure (0.8 mT) on CD4 T cells under Th9-polarizing conditions. The authors report increased Th9-associated responses including IL-9 secretion, transcription factor changes (including early GATA3), and increased STAT5/STAT6 phosphorylation alongside…
Evaluation of the Validity of a Nonlinear J-Shaped Dose-Response Relationship in Cancers Induced by Exposure to Radiofrequency Electromagnetic Fields.
Research
RF Safe Research Library
Jan 1, 2019
This review discusses the controversial evidence on mobile phone RF-EMF exposure and brain cancer. The authors argue that exposure magnitude may be a key factor contributing to inconsistent findings. They discuss evidence supporting a nonlinear J-shaped dose-response relationship for RF-EMF-related carcinogenesis.
[The reaction of the circulatory system to stress and electromagnetic fields emitted by mobile phones - 24-h monitoring of ECG and blood pressure].
Research
RF Safe Research Library
Jan 1, 2019
In a worker sample undergoing 24-hour ECG and ambulatory blood pressure monitoring, higher self-reported daily mobile phone use (>60 minutes) was associated with higher systolic blood pressure in office measurement and at night. Higher occupational stress was associated with higher systolic and diastolic blood…
Residential exposure to ultra high frequency electromagnetic fields emitted by Global System for Mobile (GSM) antennas and amyotrophic lateral sclerosis incidence: A geo-epidemiological population-based study.
Research
RF Safe Research Library
Jan 1, 2019
This geo-epidemiological population-based study in Limousin (France) assessed modeled residential UHF-EMF exposure from GSM antennas and ALS incidence from 2000–2012. The authors report a statistically significant exposure–response trend and higher ALS risk in the highest exposure category versus non-exposure in both…
Genotoxic and cytotoxic effects of 50 Hz 1 mT electromagnetic field on larval rainbow trout (Oncorhynchus mykiss), Baltic clam (Limecola balthica) and common ragworm (Hediste diversicolor).
Research
RF Safe Research Library
Jan 1, 2019
This animal study assessed genotoxic and cytotoxic responses in aquatic species exposed to a 50 Hz, 1 mT electromagnetic field. Nuclear abnormality assays indicated significant increases in multiple genotoxicity endpoints across species, with the most pronounced effects in Baltic clam gill cells. Cytotoxicity…
Non-Ionizing Radiation for Cardiac Human Amniotic Mesenchymal Stromal Cell Commitment: A Physical Strategy in Regenerative Medicine.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study exposed human amniotic mesenchymal stromal cells to an ELF-EMF stimulus (7 Hz, 2.5 µT) and compared responses with a nitric oxide chemical treatment. The authors report reduced cell proliferation with no change in metabolic activity, vitality, or apoptosis after ELF-EMF exposure. They also report…
Effect of acute exposure to radiofrequency electromagnetic fields emitted by a mobile phone (GSM 900 MHz) on electrodermal responsiveness in healthy human.
Research
RF Safe Research Library
Jan 1, 2018
This study examined whether acute GSM 900 MHz mobile phone exposure affects electrodermal activity responses to auditory stimuli in 28 young volunteers. The authors report no exposure-related changes in SCR latency, amplitude, integral, or number of responses. Session differences in skin conductance/tonic…
Eotaxin‑1 and MCP‑1 serve as circulating indicators in response to power frequency electromagnetic field exposure in mice.
Research
RF Safe Research Library
Jan 1, 2018
This animal study exposed young Balb/c mice to constant 50 Hz power-frequency EMF at 0.1, 0.5, or 2.5 mT for 90 days. Body weight did not differ between exposed and control groups, but serum chemokine profiles showed exposure-related changes. EOTAXIN-1 and MCP-1 were significantly increased at 0.5 mT, which the…
Effects of electromagnetic field, cisplatin and morphine on cytotoxicity and expression levels of DNA repair genes.
Research
RF Safe Research Library
Jan 1, 2018
This in vitro study examined how morphine, a 50-Hz 0.50 mT electromagnetic field (intermittent), and cisplatin co-treatments affected DNA repair gene expression and cytotoxicity in MCF-7 and SH-SY5Y cells. Morphine alone was reported to down-regulate examined DNA repair genes, whereas morphine plus EMF did not…
A Single Exposure to GSM-1800 MHz Signals in the Course of an Acute Neuroinflammatory Reaction can Alter Neuronal Responses and Microglial Morphology in the Rat Primary Auditory Cortex.
Research
RF Safe Research Library
Jan 1, 2018
This animal study examined whether acute GSM-1800 MHz exposure affects the auditory cortex during experimentally induced neuroinflammation. In LPS-treated rats, a single 2-hour head-only exposure (average SAR 1.55 W/kg in auditory cortex) was associated with altered microglial morphology and reduced neuronal activity…