Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study exposed human osteoarthritic and non-osteoarthritic chondrocyte pellets to a sinusoidal 15 Hz electromagnetic field at 5 mT or 8 mT for 7 days. Under 5 mT, osteoarthritic chondrocytes showed increased expression of cartilage-related genes (COL2A1 and ACAN) compared with controls, while…
Different profiles of the mRNA levels of DNA repair genes in MCF-7 and SH-SY5Y cells after treatment with combination of cisplatin, 50-Hz electromagnetic field and bleomycin.
Research
RF Safe Research Library
Jan 1, 2017
This in vitro study examined whether a 50-Hz, 0.50 mT intermittent electromagnetic field modifies responses to cisplatin and bleomycin in MCF-7 and SH-SY5Y cells. The authors report increased susceptibility in MCF-7 cells with EMF added to cisplatin+bleomycin, while SH-SY5Y susceptibility was unchanged. They also…
Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms.
Research
RF Safe Research Library
Jan 1, 2017
This animal study exposed Eisenia fetida earthworms to 900 MHz electromagnetic fields at 10–120 V/m for 2 hours (with additional tests of longer exposure, modulation, and recovery). The authors report significant DNA modifications across exposure treatments and a decrease in probe hybridisation sites persisting after…
Effects of four kinds of electromagnetic fields (EMF) with different frequency spectrum bands on ovariectomized osteoporosis in mice.
Research
RF Safe Research Library
Jan 1, 2017
This animal study tested four frequency-band EMF exposures (1–50,000 Hz variants) in an ovariectomized mouse model of osteoporosis over 8 weeks (3 h/day). Low- and band-pass exposures increased bone formation markers and osteogenesis-related gene expression, while high-pass exposure decreased both formation and…
Quantum mechanical model for the anticarcinogenic effect of extremely-low-frequency electromagnetic fields on early chemical hepatocarcinogenesis.
Research
RF Safe Research Library
Jan 1, 2017
This study develops a quantum-mechanical radical pair mechanism model to examine how an extremely-low-frequency electromagnetic field (ELF-EMF) might influence early chemical hepatocarcinogenesis in rats. The model evaluates singlet-state recombination and quantum yield under a low magnetic field effect, proposing…
The effects of radio-frequency electromagnetic fields on T cell function during development
Research
RF Safe Research Library
Jan 1, 2015
This animal study exposed developing Sprague Dawley rats to 2.14 GHz W-CDMA RF-EMF at a whole-body SAR of 0.2 W/kg for 9 weeks (20 h/day). No differences were reported in multiple T cell population measures across blood, spleen, and thymus. Some Th1/Th2-related genes were upregulated (notably in thymus), but serum…
Electromagnetic fields counteract IL-1β activity during chondrogenesis of bovine mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2015
This in vitro study examined whether electromagnetic fields (EMFs) influence chondrogenic differentiation of bovine mesenchymal stem cell pellets, with and without the inflammatory cytokine IL-1β. The authors report EMFs had limited effects on chondrogenesis in the absence of inflammation, but in the presence of…
[The activity of prooxidant-antioxidant system in loach embryos under the action of microwave radiation].
Research
RF Safe Research Library
Jan 1, 2014
This animal study examined oxidative stress and antioxidant defenses in loach embryos exposed to GSM 900 MHz microwave radiation (SAR 1.1 W/kg) for 1–20 minutes during early embryogenesis. The authors report significant changes in lipid peroxidation products and altered antioxidant enzyme activities. They conclude…
[State of the reproductive systemin in male rats of 1st generation obtained from irradiated parents and exposed to electromagnetic radiation (897 MHz) during embryogenesis and postnatal development].
Research
RF Safe Research Library
Jan 1, 2014
This animal study examined prolonged 897 MHz electromagnetic radiation exposure (8 h/day) in first-generation male rats from irradiated parents, with exposure during embryogenesis and postnatal development. The abstract reports fewer births and a sex ratio shift toward more males. It also reports accelerated male…
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Research
RF Safe Research Library
Jan 1, 2012
This in vitro study examined whether low-frequency electromagnetic fields (a complex multiple waveform field and a 50 Hz sine wave) alter inflammatory gene and protein responses in human immune cells. Across time course experiments in THP-1 cells and primary monocytes/macrophages, the authors report no significant…
Human keratinocytes in culture exhibit no response when exposed to short duration, low amplitude, high frequency (900 MHz) electromagnetic fields in a reverberation chamber.
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study exposed normal human epidermal keratinocytes to non-thermal 900 MHz electromagnetic fields in a mode-stirred reverberation chamber under two short-duration conditions. Microarray analysis found only limited gene modulation (20 genes) with small expression ratios and no shared genes across…
Effects of low frequency electromagnetic fields on the chondrogenic differentiation of human mesenchymal stem cells.
Research
RF Safe Research Library
Jan 1, 2011
This in vitro study examined whether extremely low-frequency magnetic fields affect chondrogenic differentiation of human mesenchymal stem cells in pellet culture. Cells exposed for 3 weeks to a homogeneous sinusoidal 5 mT magnetic field showed increased collagen type II expression (significant at passage 6) and…
[Effect of 1.8 GHz radiofrequency electromagnetic fields on gene expression of rat neurons].
Research
RF Safe Research Library
Jan 1, 2008
This in vitro study exposed primary cultured rat neurons to 1.8 GHz RF-EMF at an average SAR of 2 W/kg and assessed gene expression changes. The authors report multiple differentially expressed genes after 24 h intermittent exposure and confirm exposure-dependent changes in Egr-1, Mbp, and Plp by semi-quantitative…
Ultrastructural alterations and occurrence of apoptosis in developing follicles exposed to low frequency electromagnetic field in rat ovary.
Research
RF Safe Research Library
Jan 1, 2007
This animal study examined rat ovaries after chronic exposure to a 3 mT low-frequency electromagnetic field for 4 hours per day over 4 months. Using TEM and TUNEL, the authors report ultrastructural alterations in oocytes and more frequent apoptosis-associated changes in granulosa and corona radiata cells versus…